Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes

Early prediction of preeclampsia in pregnancy with cell-free RNA

(2022) Mira N. Moufarrej et al.   NATURE

Preeclampsia

(2022) Laura A. Magee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology studies

(2022) Nándor Gábor Than et al.   PLACENTA

Gestational hypertension and “severe” disease: time for a change

(2022) Steven L. Clark et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Four major patterns of placental injury: a stepwise guide for understanding and implementing the 2016 Amsterdam consensus

(2021) Raymond W. Redline et al.   MODERN PATHOLOGY

Data-Driven Modeling of Pregnancy-Related Complications

(2021) Camilo Espinosa et al.   TRENDS IN MOLECULAR MEDICINE

Transcriptomic Profiling of Human Placenta in Gestational Diabetes Mellitus at the Single-Cell Level

(2021) Yuqi Yang et al.   Frontiers in Endocrinology

A single–cell type transcriptomics map of human tissues

(2021) Max Karlsson et al.   Science Advances

RNA Network Interactions During Differentiation of Human Trophoblasts

(2021) Tianjiao Chu et al.   Frontiers in Cell and Developmental Biology

The reactome pathway knowledgebase 2022

(2021) Marc Gillespie et al.   NUCLEIC ACIDS RESEARCH

Combining Biomarkers to Predict Pregnancy Complications and Redefine Preeclampsia

(2020) Holger Stepan et al.   HYPERTENSION

Gestational age and hospital admissions during childhood: population based, record linkage study in England (TIGAR study)

(2020) Victoria Coathup et al.   BMJ-British Medical Journal

Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm

(2020) Hudson P. Santos Jr et al.   Molecular Autism

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Metabolomics Identifies Placental Dysfunction and Confirms Flt-1 (FMS-Like Tyrosine Kinase Receptor 1) Biomarker Specificity

(2019) Marie Austdal et al.   HYPERTENSION

Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease

(2018) Fatima Crispi et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Pathophysiology of placental-derived fetal growth restriction

(2018) Graham J. Burton et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Multiomics Modeling of the Immunome, Transcriptome, Microbiome, Proteome, and Metabolome Adaptations During Human Pregnancy

(2018) Mohammad Sajjad Ghaemi et al.   BIOINFORMATICS

Noninvasive blood tests for fetal development predict gestational age and preterm delivery

(2018) Thuy T. M. Ngo et al.   SCIENCE

Mixed Graphical Models for Integrative Causal Analysis with Application to Chronic Lung Disease Diagnosis and Prognosis

(2018) Andrew J Sedgewick et al.   BIOINFORMATICS

The frequency and type of placental histologic lesions in term pregnancies with normal outcome

(2018) Roberto Romero et al.   JOURNAL OF PERINATAL MEDICINE

Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia

(2018) Nandor Gabor Than et al.   Frontiers in Immunology

The clinical heterogeneity of preeclampsia is related to both placental gene expression and placental histopathology

(2018) Samantha J. Benton et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Placental transcriptional and histologic subtypes of normotensive fetal growth restriction are comparable to preeclampsia

(2018) Isaac Gibbs et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Genetic Associations with Gestational Duration and Spontaneous Preterm Birth

(2017) Ge Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pregnancy as a window to future health: maternal placental syndromes and short-term cardiovascular outcomes

(2016) Mary Ashley Cain et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Sampling and Definitions of Placental Lesions: Amsterdam Placental Workshop Group Consensus Statement

(2016) T. Yee Khong et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Unsupervised Placental Gene Expression Profiling Identifies Clinically Relevant Subclasses of Human PreeclampsiaNovelty and Significance

(2016) Katherine Leavey et al.   HYPERTENSION

Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia

(2016) Harald Zeisler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Placental Origins of Chronic Disease

(2016) Graham J. Burton et al.   PHYSIOLOGICAL REVIEWS

Placental histological patterns and uterine artery Doppler velocimetry in pregnancies complicated by early or late pre-eclampsia

(2016) R. Orabona et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Consensus definition of fetal growth restriction: a Delphi procedure

(2016) S. J. Gordijn et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Learning the Structure of Mixed Graphical Models

(2015) Jason D. Lee et al.   JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

Large Scale Aggregate Microarray Analysis Reveals Three Distinct Molecular Subclasses of Human Preeclampsia

(2015) Katherine Leavey et al.   PLoS One

Similarity network fusion for aggregating data types on a genomic scale

(2014) Bo Wang et al.   NATURE METHODS

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

(2014) Erika Assarsson et al.   PLoS One

Preterm labor: One syndrome, many causes

(2014) R. Romero et al.   SCIENCE

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

The long-term renal and cardiovascular consequences of prematurity

(2012) Carolyn L. Abitbol et al.   Nature Reviews Nephrology

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

A global reference for fetal-weight and birthweight percentiles

(2011) Rafael T Mikolajczyk et al.   LANCET

The “Great Obstetrical Syndromes” are associated with disorders of deep placentation

(2010) Ivo Brosens et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Pre-eclampsia

(2010) Eric AP Steegers et al.   LANCET

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Epidemiology and causes of preterm birth

(2008) Robert L Goldenberg et al.   LANCET