Focused acoustic vortex-mediated sonochemotherapy for the amplification of immunogenic cell death combined with checkpoint blockade to potentiate cancer immunotherapy

Thermal immuno-nanomedicine in cancer

(2023) Zhe Yang et al.   Nature Reviews Clinical Oncology

Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer

(2022) Namrata S. Patil et al.   CANCER CELL

Turning cold tumors hot: from molecular mechanisms to clinical applications

(2022) Jiahui Zhang et al.   TRENDS IN IMMUNOLOGY

Focused Acoustic Vortex-Regulated Composite Nanodroplets Combined with Checkpoint Blockade for High-Performance Tumor Synergistic Therapy

(2022) Pengying Wu et al.   ACS Applied Materials & Interfaces

Immunosonodynamic Therapy Designed with Activatable Sonosensitizer and Immune Stimulant Imiquimod

(2022) Huali Lei et al.   ACS Nano

Spatiotemporal control of engineered bacteria to express interferon-γ by focused ultrasound for tumor immunotherapy

(2022) Yuhao Chen et al.   Nature Communications

Manganese Coordination Micelles That Activate Stimulator of Interferon Genes and Capture In Situ Tumor Antigens for Cancer Metalloimmunotherapy

(2022) Jiexin Li et al.   ACS Nano

Enhanced Sonothrombolysis Induced by High-Intensity Focused Acoustic Vortex

(2022) Shifang Guo et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Polysaccharide Nanodonuts for Photochemotherapy‐Amplified Immunogenic Cell Death to Potentiate Systemic Antitumor Immunity Against Hepatocellular Carcinoma

(2022) Yaping Wang et al.   ADVANCED FUNCTIONAL MATERIALS

PD-L1 as a biomarker of response to immune-checkpoint inhibitors

(2021) Deborah Blythe Doroshow et al.   Nature Reviews Clinical Oncology

Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia coli Combined with Immunogenic Cell Death for Cancer Immunotherapy

(2021) Baicheng Wei et al.   NANO LETTERS

Immune checkpoint inhibitors in melanoma

(2021) Matteo S Carlino et al.   LANCET

Double enhancement of immunogenic cell death and antigen presentation for cancer immunotherapy

(2021) Xiang Xiong et al.   Nano Today

Immunogenic camptothesome nanovesicles comprising sphingomyelin-derived camptothecin bilayers for safe and synergistic cancer immunochemotherapy

(2021) Zhiren Wang et al.   Nature Nanotechnology

Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell–cold solid tumors

(2021) Brian Belmontes et al.   Science Translational Medicine

Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy

(2021) Victoria S. Pelly et al.   Cancer Discovery

Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer

(2021) Yuanyuan Zhang et al.   CANCER CELL

Hallmarks of response, resistance, and toxicity to immune checkpoint blockade

(2021) Golnaz Morad et al.   CELL

The tumour microenvironment in pancreatic cancer — clinical challenges and opportunities

(2020) Won Jin Ho et al.   Nature Reviews Clinical Oncology

Management of glioblastoma: State of the art and future directions

(2020) Aaron C. Tan et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Pancreatic cancer

(2020) Jonathan D Mizrahi et al.   LANCET

The NK cell–cancer cycle: advances and new challenges in NK cell–based immunotherapies

(2020) Tobias Bald et al.   NATURE IMMUNOLOGY

Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death

(2020) Hongzhang Deng et al.   Nature Communications

Highly Penetrable and On-Demand Oxygen Release with Tumor Activity Composite Nanosystem for Photothermal/Photodynamic Synergetic Therapy

(2020) Ya Wang et al.   ACS Nano

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Hyperthermia: The Optimal Treatment to Overcome Radiation Resistant Hypoxia

(2019) Pernille Elming et al.   Cancers

Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice

(2019) Wenwen Yue et al.   Nature Communications

Tumor Ablation and Therapeutic Immunity Induction by an Injectable Peptide Hydrogel

(2018) Honglin Jin et al.   ACS Nano

Bioinspired Hybrid Protein Oxygen Nanocarrier Amplified Photodynamic Therapy for Eliciting Anti-tumor Immunity and Abscopal Effect

(2018) Zhikuan Chen et al.   ACS Nano

T Cell Dysfunction in Cancer

(2018) Daniela S. Thommen et al.   CANCER CELL

Dispersing surface-modified imogolite nanotubes in polar and non-polar solvents

(2018) Ming Li et al.   JOURNAL OF NANOPARTICLE RESEARCH

Induction of enhanced immunogenic cell death through ultrasound-controlled release of doxorubicin by liposome-microbubble complexes

(2018) Feng-Ying Huang et al.   OncoImmunology

Immunogenic cell death in anticancer chemotherapy and its impact on clinical studies

(2018) Qiang Wang et al.   CANCER LETTERS

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

(2018) Sanjeev Mariathasan et al.   NATURE

Metalloporphyrin-Encapsulated Biodegradable Nanosystems for Highly Efficient Magnetic Resonance Imaging-Guided Sonodynamic Cancer Therapy

(2017) Ping Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ultrasound-triggered release of sinoporphyrin sodium from liposome-microbubble complexes and its enhanced sonodynamic toxicity in breast cancer

(2017) Yixiang Li et al.   Nano Research

An MSN-PEG-IP drug delivery system and IL13Rα2 as targeted therapy for glioma

(2017) Jinlong Shi et al.   Nanoscale

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

(2016) Chunbai He et al.   Nature Communications

Systematic review of high-intensity focused ultrasound ablation in the treatment of breast cancer

(2015) M. C. L. Peek et al.   BRITISH JOURNAL OF SURGERY

CO2 bubbling-based 'Nanobomb' System for Targetedly Suppressing Panc-1 Pancreatic Tumor via Low Intensity Ultrasound-activated Inertial Cavitation

(2015) Kun Zhang et al.   Theranostics

Generation of Amphiphilic Janus Bubbles and Their Behavior at an Air-Water Interface

(2011) Teresa Brugarolas et al.   ADVANCED FUNCTIONAL MATERIALS

Mild Elevation of Body Temperature Reduces Tumor Interstitial Fluid Pressure and Hypoxia and Enhances Efficacy of Radiotherapy in Murine Tumor Models

(2011) A. Sen et al.   CANCER RESEARCH

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Production of uniformly sized serum albumin and dextrose microbubbles

(2011) Michael J. Borrelli et al.   ULTRASONICS SONOCHEMISTRY

Microbubble size isolation by differential centrifugation

(2008) Jameel A. Feshitan et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE