The expanding roles of PI4P and PI(4,5)P2 at the plasma membrane: Role of phosphatidylinositol transfer proteins

Individual phosphatidylinositol transfer proteins have distinct functions that do not involve lipid transfer activity

(2023) Charles S. Abrams et al.   Blood Advances

The lipid transfer proteins Nir2 and Nir3 sustain phosphoinositide signaling and actin dynamics during phagocytosis

(2023) Mayis Kaba et al.   JOURNAL OF CELL SCIENCE

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction

(2023) Yu-Te Yeh et al.   Nature Communications

Gasdermin D pores are dynamically regulated by local phosphoinositide circuitry

(2022) Ana Beatriz Santa Cruz Garcia et al.   Nature Communications

Plasma membrane phosphatidylinositol (4,5)-bisphosphate is critical for determination of epithelial characteristics

(2022) Kaori Kanemaru et al.   Nature Communications

Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration

(2022) Zhigang Xie et al.   Cell Reports

A p53–phosphoinositide signalosome regulates nuclear AKT activation

(2022) Mo Chen et al.   NATURE CELL BIOLOGY

Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides

(2022) Fu-Long Li et al.   Nature Chemical Biology

Synaptotagmin rings as high-sensitivity regulators of synaptic vesicle docking and fusion

(2022) Jie Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics

(2022) John Janetzko et al.   CELL

Courier service for phosphatidylinositol: PITPs deliver on demand

(2021) Tim G. Ashlin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

(2020) James P. Zewe et al.   JOURNAL OF CELL BIOLOGY

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol

(2020) Joshua G. Pemberton et al.   JOURNAL OF CELL BIOLOGY

Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane

(2020) Matilda Katan et al.   Essays in Biochemistry

Nir2 is an effector of VAPs necessary for efficient HCV replication and PI(4)P enrichment at the viral replication organelle

(2019) Hongliang Wang et al.   JOURNAL OF VIROLOGY

Neuronal ER–plasma membrane junctions organized by Kv2–VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis

(2019) Michael Kirmiz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PI(4,5)P2controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

(2018) Mira Sohn et al.   JOURNAL OF CELL BIOLOGY

Phosphatidylinositol and phosphatidic acid transport between the ER and plasma membrane during PLC activation requires the Nir2 protein

(2016) Y. J. Kim et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

RdgB  reciprocally transfers PA and PI at ER-PM contact sites to maintain PI(4,5)P2 homoeostasis during phospholipase C signalling in Drosophila photoreceptors

(2016) S. Cockcroft et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phosphatidylinositol-Phosphatidic Acid Exchange by Nir2 at ER-PM Contact Sites Maintains Phosphoinositide Signaling Competence

(2015) Yeun Ju Kim et al.   DEVELOPMENTAL CELL

Phosphatidylinositol 4,5-Bisphosphate Homeostasis Regulated by Nir2 and Nir3 Proteins at Endoplasmic Reticulum-Plasma Membrane Junctions

(2015) Chi-Lun Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid landscapes and pipelines in membrane homeostasis

(2014) Joost C.M. Holthuis et al.   NATURE

Lipid signaling in Drosophila photoreceptors

(2012) Padinjat Raghu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITP  is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum

(2010) N. Carvou et al.   JOURNAL OF CELL SCIENCE

Dynamics of Lipid Transfer by Phosphatidylinositol Transfer Proteins in Cells

(2008) Sadaf Shadan et al.   TRAFFIC