Considerations, Caveats, and Suggestions for the Use of Polygenic Scores for Social and Behavioral Traits

Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

(2022) Aysu Okbay et al.   NATURE GENETICS

Indirect paths from genetics to education

(2022) Andrew J. Schork et al.   NATURE GENETICS

How can we address the uncertainties regarding the potential clinical utility of polygenic score-based tests?

(2022) Sowmiya Moorthie et al.   Personalized Medicine

The complete sequence of a human genome

(2022) Sergey Nurk et al.   SCIENCE

Human Capital Mediates Natural Selection in Contemporary Humans

(2022) David Hugh-Jones et al.   BEHAVIOR GENETICS

Polygenic Risk Scores for Cardiovascular Disease: A Scientific Statement From the American Heart Association

(2022) Jack W. O’Sullivan et al.   CIRCULATION

Schizophrenia Polygenic Risk and Experiences of Childhood Adversity: A Systematic Review and Meta-analysis

(2022) Grace E Woolway et al.   SCHIZOPHRENIA BULLETIN

Racialising genetic risk: assumptions, realities, and recommendations

(2022) Jessica P Cerdeña et al.   LANCET

Problems with Using Polygenic Scores to Select Embryos

(2021) Patrick Turley et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Polygenic Approach to Understanding Resilience to Peer Victimisation

(2021) Jessica M. Armitage et al.   BEHAVIOR GENETICS

Polygenic scores: prediction versus explanation

(2021) Robert Plomin et al.   MOLECULAR PSYCHIATRY

Clinical utility of polygenic risk scores for coronary artery disease

(2021) Derek Klarin et al.   Nature Reviews Cardiology

Variable prediction accuracy of polygenic scores within an ancestry group

(2020) Hakhamanesh Mostafavi et al.   eLife

Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk

(2020) Krishna G. Aragam et al.   CIRCULATION RESEARCH

From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases

(2020) Eddie Cano-Gamez et al.   Frontiers in Genetics

Polygenic risk scores: pleiotropy and the effect of environment

(2020) Yury Loika et al.   GeroScience

Tutorial: a guide to performing polygenic risk score analyses

(2020) Shing Wan Choi et al.   Nature Protocols

Education and wealth inequalities in healthy ageing in eight harmonised cohorts in the ATHLOS consortium: a population-based study

(2020) Yu-Tzu Wu et al.   Lancet Public Health

How White nationalists mobilize genetics: From genetic ancestry and human biodiversity to counterscience and metapolitics

(2020) Aaron Panofsky et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

Genotype imputation and variability in polygenic risk score estimation

(2020) Shang-Fu Chen et al.   Genome Medicine

Clinical use of current polygenic risk scores may exacerbate health disparities

(2019) Alicia R. Martin et al.   NATURE GENETICS

The Missing Diversity in Human Genetic Studies

(2019) Giorgio Sirugo et al.   CELL

Analysis of polygenic risk score usage and performance in diverse human populations

(2019) L. Duncan et al.   Nature Communications

A polygenic resilience score moderates the genetic risk for schizophrenia

(2019) Jonathan L. Hess et al.   MOLECULAR PSYCHIATRY

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Genetic analysis of social-class mobility in five longitudinal studies

(2018) Daniel W. Belsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nature of nurture: Effects of parental genotypes

(2018) Augustine Kong et al.   SCIENCE

Replicability and Prediction: Lessons and Challenges from GWAS

(2018) Urko M. Marigorta et al.   TRENDS IN GENETICS

Elucidating the genetic basis of social interaction and isolation

(2018) Felix R. Day et al.   Nature Communications

Use of polygenic risk scores of nicotine metabolism in predicting smoking behaviors

(2018) Li-Shiun Chen et al.   PHARMACOGENOMICS

Polygenic risk scores: a biased prediction?

(2018) Francisco M. De La Vega et al.   Genome Medicine

Polygenic prediction of the phenome, across ancestry, in emerging adulthood

(2017) Anna R. Docherty et al.   PSYCHOLOGICAL MEDICINE

Genetics and genomics of psychiatric disease

(2015) D. H. Geschwind et al.   SCIENCE

GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

(2013) C. A. Rietveld et al.   SCIENCE

Polygenic Risk and the Developmental Progression to Heavy, Persistent Smoking and Nicotine Dependence

(2013) Daniel W. Belsky et al.   JAMA Psychiatry