Notch-1 signaling activates NF-κB in human breast carcinoma MDA-MB-231 cells via PP2A-dependent AKT pathway

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Interleukin-8 upregulates integrin β3 expression and promotes estrogen receptor-negative breast cancer cell invasion by activating the PI3K/Akt/NF-κB pathway

(2015) Nan Shao et al.   CANCER LETTERS

Correlation between Activation of PI3K/AKT/mTOR Pathway and Prognosis of Breast Cancer in Chinese Women

(2015) Ling Deng et al.   PLoS One

Tropomodulin 1 Expression Driven by NF- B Enhances Breast Cancer Growth

(2014) T. Ito-Kureha et al.   CANCER RESEARCH

 -Tubulin Acetylation Elevated in Metastatic and Basal-like Breast Cancer Cells Promotes Microtentacle Formation, Adhesion, and Invasive Migration

(2014) A. E. Boggs et al.   CANCER RESEARCH

DLK1 Promotes Lung Cancer Cell Invasion through Upregulation of MMP9 Expression Depending on Notch Signaling

(2014) Lin Li et al.   PLoS One

Notch-1 Signaling Promotes the Malignant Features of Human Breast Cancer through NF-κB Activation

(2014) Li Li et al.   PLoS One

Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma

(2014) A. Stoeck et al.   Cancer Discovery

New insights into Notch1 regulation of the PI3K–AKT–mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

(2013) Eric C. Hales et al.   CELLULAR SIGNALLING

Role of a Novel Functional Variant in the PPP2R1A Promoter on the Regulation of PP2A-Aalpha and the Risk of Hepatocellular Carcinoma

(2013) Hui-Feng Chen et al.   PLoS One

Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells

(2012) Susanta Kar et al.   APOPTOSIS

Inhibition of Nuclear Factor Kappa-B Enhances the Antitumor Effect of Combination Treatment with Tumor Necrosis Factor-Alpha Gene Therapy and Gemcitabine for Pancreatic Cancer in Mice

(2012) Yuki Fujiwara et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

High-Level Expression of Notch1 Increased the Risk of Metastasis in T1 Stage Clear Cell Renal Cell Carcinoma

(2012) Qing Ai et al.   PLoS One

Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification

(2011) M. G. Cornejo et al.   BLOOD

Notch Signaling in CD66+ Cells Drives the Progression of Human Cervical Cancers

(2011) J. Bajaj et al.   CANCER RESEARCH

Cooperative Regulation of NOTCH1 Protein-Phosphatidylinositol 3-Kinase (PI3K) Signaling by NOD1, NOD2, and TLR2 Receptors Renders Enhanced Refractoriness to Transforming Growth Factor-β (TGF-β)- or Cytotoxic T-lymphocyte Antigen 4 (CTLA-4)-mediated Impairment of Human Dendritic Cell Maturation

(2011) Devram Sampat Ghorpade et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200–dependent pathway in mice

(2011) Yanan Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Invasiveness and anchorage independent growth ability augmented by PTEN inactivation through the PI3K/AKT/NFkB pathway in lung cancer cells

(2011) Hakan Akca et al.   LUNG CANCER

Receptor Activator of NF-kB (RANK) Expression in Primary Tumors Associates with Bone Metastasis Occurrence in Breast Cancer Patients

(2011) Daniele Santini et al.   PLoS One

Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFκB activation via Src-dependent blockade of PP2A

(2010) Sandra Barisic et al.   BIOCHEMICAL PHARMACOLOGY

PP2A Regulatory Subunit PP2A-B′ Counteracts S6K Phosphorylation

(2010) Katrin Hahn et al.   Cell Metabolism

High Notch1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype

(2010) Sarah J Zardawi et al.   HISTOPATHOLOGY

Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells

(2010) Zhiwei Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mechanism of PP2A-mediated IKKβ dephosphorylation: a systems biological approach

(2009) Johannes Witt et al.   BMC Systems Biology

Pomegranate Fruit Extract Impairs Invasion and Motility in Human Breast Cancer

(2009) Gazala N. Khan et al.   INTEGRATIVE CANCER THERAPIES

Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma

(2009) Etienne Meylan et al.   NATURE

Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells

(2008) L L Song et al.   ONCOGENE