Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs
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Title
Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs
Authors
Keywords
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Journal
ANTIVIRAL RESEARCH
Volume 219, Issue -, Pages 105718
Publisher
Elsevier BV
Online
2023-09-25
DOI
10.1016/j.antiviral.2023.105718
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- (2022) Zhujun Cao et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2021) Robert T. Schooley et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2020) Richard T. Eastman et al. ACS Central Science
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