Tumor-agnostic plasma assay for circulating tumor DNA detects minimal residual disease and predicts outcome in locally advanced squamous cell carcinoma of the head and neck

Osimertinib treatment based on plasma T790M monitoring in patients with EGFR-mutant non-small-cell lung cancer (NSCLC): EORTC Lung Cancer Group 1613 APPLE phase II randomized clinical trial

(2023) J. Remon et al.   ANNALS OF ONCOLOGY

Monitoring of T790M in plasma ctDNA of advanced EGFR-mutant NSCLC patients on first- or second-generation tyrosine kinase inhibitors

(2023) Chun-Ta Huang et al.   BMC CANCER

IMvigor011: a study of adjuvant atezolizumab in patients with high-risk MIBC who are ctDNA+ post-surgery

(2023) Francesca Jackson-Spence et al.   Future Oncology

Multimodal detection in plasma of molecular residual disease (MRD) in locally advanced head and neck squamous cell carcinoma (LA-HNSCC).

(2023) Enrique Sanz Garcia et al.   JOURNAL OF CLINICAL ONCOLOGY

Next-generation sequencing (NGS) profiling of matched tumor and circulating tumor DNA (ctDNA) in head and neck squamous cell carcinoma (HNSCC)

(2023) Panagiota Economopoulou et al.   ORAL ONCOLOGY

Liquid BIOpsy for MiNimal RESidual DiSease Detection in Head and Neck Squamous Cell Carcinoma (LIONESS)—a personalised circulating tumour DNA analysis in head and neck squamous cell carcinoma

(2022) Susanne Flach et al.   BRITISH JOURNAL OF CANCER

Residual ctDNA after treatment predicts early relapse in patients with early-stage non-small cell lung cancer

(2022) D. Gale et al.   ANNALS OF ONCOLOGY

Individualized circulating tumor DNA monitoring in head and neck squamous cell carcinoma

(2022) Ryunosuke Kogo et al.   Cancer Medicine

Accuracy of high-risk HPV DNA PCR, p16(INK4a) immunohistochemistry or the combination of both to diagnose HPV-driven oropharyngeal cancer

(2022) Cindy Simoens et al.   BMC INFECTIOUS DISEASES

Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial

(2021) Nancy Y Lee et al.   LANCET ONCOLOGY

Tumor-Naïve Multimodal Profiling of Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma

(2021) Justin M. Burgener et al.   CLINICAL CANCER RESEARCH

Plasma Circulating Tumor HPV DNA for the Surveillance of Cancer Recurrence in HPV-Associated Oropharyngeal Cancer

(2020) Bhishamjit S. Chera et al.   JOURNAL OF CLINICAL ONCOLOGY

Current applications and challenges of circulating tumor DNA (ctDNA) in squamous cell carcinoma of the head and neck (SCCHN)

(2020) Rachel Galot et al.   CANCER TREATMENT REVIEWS

Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer

(2020) Jian Yang et al.   Cell Death & Disease

Dynamics of cell-free tumour DNA correlate with treatment response of head and neck cancer patients receiving radiochemotherapy

(2020) Franz J. Hilke et al.   RADIOTHERAPY AND ONCOLOGY

Design and Testing of a Custom Melanoma Next Generation Sequencing Panel for Analysis of Circulating Tumor DNA

(2020) Russell J. Diefenbach et al.   Cancers

Breast Cancer Detection and Treatment Monitoring Using a Noninvasive Prenatal Testing Platform: Utility in Pregnant and Nonpregnant Populations

(2020) Liesbeth Lenaerts et al.   CLINICAL CHEMISTRY

Rapid Clearance Profile of Plasma Circulating Tumor HPV Type 16 DNA during Chemoradiotherapy Correlates with Disease Control in HPV-Associated Oropharyngeal Cancer

(2019) Bhishamjit S Chera et al.   CLINICAL CANCER RESEARCH

Afatinib vs Placebo as Adjuvant Therapy After Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

(2019) Barbara Burtness et al.   JAMA Oncology

Circulating tumor DNA analysis for detection of minimal residual disease after chemoradiotherapy for localized esophageal cancer

(2019) Tej D. Azad et al.   GASTROENTEROLOGY

Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer

(2019) Jeanne Tie et al.   JAMA Oncology

Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling

(2017) Aadel A. Chaudhuri et al.   Cancer Discovery

PET-CT Surveillance versus Neck Dissection in Advanced Head and Neck Cancer

(2016) Hisham Mehanna et al.   NEW ENGLAND JOURNAL OF MEDICINE

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

(2015) Yuxuan Wang et al.   Science Translational Medicine

Integrative Genomic Characterization of Oral Squamous Cell Carcinoma Identifies Frequent Somatic Drivers

(2013) C. R. Pickering et al.   Cancer Discovery

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS