Shikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK Pathway

The clinical phenotypes of autoimmune hepatitis: A comprehensive review

(2016) Qixia Wang et al.   JOURNAL OF AUTOIMMUNITY

Ceramide generation during curcumin-induced apoptosis is controlled by crosstalk among Bcl-2, Bcl-xL, caspases and glutathione

(2015) Abo Bakr Abdel Shakor et al.   CELLULAR SIGNALLING

Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in mice

(2015) Kele Cui et al.   JOURNAL OF HEPATOLOGY

Protective Effects of N-Acetylcysteine in Concanavalin A-Induced Hepatitis in Mice

(2015) Chengfen Wang et al.   MEDIATORS OF INFLAMMATION

Autophagy and autophagy-related proteins in the immune system

(2015) Shusaku T Shibutani et al.   NATURE IMMUNOLOGY

Protective Effects of Astaxanthin on ConA-Induced Autoimmune Hepatitis by the JNK/p-JNK Pathway-Mediated Inhibition of Autophagy and Apoptosis

(2015) Jingjing Li et al.   PLoS One

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice

(2014) A. Gonzalez-Rodriguez et al.   Disease Models & Mechanisms

Protective Effect of Ellagic Acid on Concanavalin A-Induced Hepatitis via Toll-Like Receptor and Mitogen-Activated Protein Kinase/Nuclear Factor κB Signaling Pathways

(2014) Jae Hong Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis

(2014) Chuanyong Guo et al.   Drug Design Development and Therapy

The Translocation of Nuclear Molecules During Inflammation and Cell Death

(2013) David S. Pisetsky   ANTIOXIDANTS & REDOX SIGNALING

ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury

(2013) Naoko Kamo et al.   HEPATOLOGY

Autoimmune hepatitis

(2013) Michael A Heneghan et al.   LANCET

Shikonin and its derivatives: a patent review

(2012) Rubing Wang et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Shikonin ameliorates cerulein-induced acute pancreatitis in mice

(2012) Jie Xiong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Immune mechanisms of Concanavalin A model of autoimmune hepatitis

(2012) Hai-Xia Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling

(2010) Shao-Chih Chiu et al.   BMC GENOMICS

Shikonin reduces oedema induced by phorbol ester by interfering with IκBα degradation thus inhibiting translocation of NF-κB to the nucleus

(2010) I Andújar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Shikonin inhibits maturation of bone marrow-derived dendritic cells and suppresses allergic airway inflammation in a murine model of asthma

(2010) Chen-Chen Lee et al.   BRITISH JOURNAL OF PHARMACOLOGY

Restoration of p53 Functions Protects Cells from Concanavalin A-Induced Apoptosis

(2010) A.R.M. R. Amin et al.   MOLECULAR CANCER THERAPEUTICS

Interleukin-1  (IL-1 ) Processing Pathway

(2010) A. Weber et al.   Science Signaling

CD4 T cells in hepatic immune tolerance

(2009) Antonella Carambia et al.   JOURNAL OF AUTOIMMUNITY

Differential Roles of JNK in ConA/GalN and ConA-Induced Liver Injury in Mice

(2008) Hong-Min Ni et al.   AMERICAN JOURNAL OF PATHOLOGY

Exendin-4 Protects  -Cells From Interleukin-1 -Induced Apoptosis by Interfering With the c-Jun NH2-Terminal Kinase Pathway

(2008) M. Ferdaoussi et al.   DIABETES

Suppressor of cytokine signaling 1 protects mice against concanavalin A-induced hepatitis by inhibiting apoptosis

(2008) Takehiro Torisu et al.   HEPATOLOGY