A peptide-based pH-sensitive drug delivery system for targeted ablation of cancer cells

Principles in the design of ligand-targeted cancer therapeutics and imaging agents

(2015) Madduri Srinivasarao et al.   NATURE REVIEWS DRUG DISCOVERY

Targeted nanotechnology for cancer imaging

(2014) Randall Toy et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeted Bioimaging and Photodynamic Therapy of Cancer Cells with an Activatable Red Fluorescent Bioprobe

(2014) Fang Hu et al.   ANALYTICAL CHEMISTRY

Combining Topology and Sequence Design for the Discovery of Potent Antimicrobial Peptide Dendrimers against Multidrug-ResistantPseudomonas aeruginosa

(2014) Michaela Stach et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

(2014) Ravi V. J. Chari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Poly(2-ethyl-2-oxazoline)–Doxorubicin Conjugate-Based Dual Endosomal pH-Sensitive Micelles with Enhanced Antitumor Efficacy

(2014) Jinwen Li et al.   BIOCONJUGATE CHEMISTRY

Cell-SELEX-based selection of aptamers that recognize distinct targets on metastatic colorectal cancer cells

(2014) Wan-Ming Li et al.   BIOMATERIALS

A targeted theranostic platinum(iv) prodrug containing a luminogen with aggregation-induced emission (AIE) characteristics for in situ monitoring of drug activation

(2014) Youyong Yuan et al.   CHEMICAL COMMUNICATIONS

Nanomaterials for Theranostics: Recent Advances and Future Challenges

(2014) Eun-Kyung Lim et al.   CHEMICAL REVIEWS

Current Progress of Aptamer-Based Molecular Imaging

(2014) A. Z. Wang et al.   JOURNAL OF NUCLEAR MEDICINE

Automated Modular Synthesis of Aptamer–Drug Conjugates for Targeted Drug Delivery

(2014) RuoWen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A targeted approach to cancer imaging and therapy

(2014) Chun Li   NATURE MATERIALS

Lighting up tumours

(2014) Daishun Ling et al.   NATURE MATERIALS

Multi-resolution 3D visualization of the early stages of cellular uptake of peptide-coated nanoparticles

(2014) Kevin Welsher et al.   Nature Nanotechnology

Identification and Characterization of a Suite of Tumor Targeting Peptides for Non-Small Cell Lung Cancer

(2014) Michael J. McGuire et al.   Scientific Reports

Rational Design of Multifunctional Upconversion Nanocrystals/Polymer Nanocomposites for Cisplatin (IV) Delivery and Biomedical Imaging

(2013) Ping'an Ma et al.   ADVANCED MATERIALS

Micellar nanoparticle formation via electrostatic interactions for delivering multinuclear platinum(ii) drugs

(2013) Haihua Xiao et al.   CHEMICAL COMMUNICATIONS

Tetraphenylethylene Conjugated with a Specific Peptide as a Fluorescence Turn-On Bioprobe for the Highly Specific Detection and Tracing of Tumor Markers in Live Cancer Cells

(2013) Yanyan Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Photosensitive Pt(IV)–azide prodrug-loaded nanoparticles exhibit controlled drug release and enhanced efficacy in vivo

(2013) Haihua Xiao et al.   JOURNAL OF CONTROLLED RELEASE

Folate-Based Near-Infrared Fluorescent Theranostic Gemcitabine Delivery

(2013) Zhigang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Retaining Antibodies in Tumors with a Self-Assembling Injectable System

(2013) Yi Wen et al.   MOLECULAR PHARMACEUTICS

Antibody–drug conjugates

(2013) Rachel S. Zolot et al.   NATURE REVIEWS DRUG DISCOVERY

Glucose conjugation for the specific targeting and treatment of cancer

(2013) Emilia C. Calvaresi et al.   Chemical Science

A novel probe for the non-invasive detection of tumor-associated inflammation

(2013) Anthony Balducci et al.   OncoImmunology

Antibody-Drug Conjugates in Cancer Therapy

(2012) Eric L. Sievers et al.   Annual Review of Medicine

pH-triggered blooming of ‘nano-flowers’ for tumor intracellular drug delivery

(2012) Zhefan Yuan et al.   CHEMICAL COMMUNICATIONS

Acid-Active Cell-Penetrating Peptides for in Vivo Tumor-Targeted Drug Delivery

(2012) Erlei Jin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembling doxorubicinprodrug forming nanoparticles for cancer chemotherapy: synthesis and anticancer study in vitro and in vivo

(2012) Pengfei Gou et al.   Journal of Materials Chemistry B

Prodrugs for improving tumor targetability and efficiency

(2011) Rubi Mahato et al.   ADVANCED DRUG DELIVERY REVIEWS

Acid-Activatable Prodrug Nanogels for Efficient Intracellular Doxorubicin Release

(2011) Fuxing Zhan et al.   BIOMACROMOLECULES

Highly Specific Targeting and Imaging of Live Cancer Cells by Using a Peptide Probe Developed from Rationally Designed Peptides

(2011) Yanyan Huang et al.   CHEMBIOCHEM

Safety, Pharmacokinetics, and Activity of GRN1005, a Novel Conjugate of Angiopep-2, a Peptide Facilitating Brain Penetration, and Paclitaxel, in Patients with Advanced Solid Tumors

(2011) R. Kurzrock et al.   MOLECULAR CANCER THERAPEUTICS

Biological Evaluation of a Novel Doxorubicin−Peptide Conjugate for Targeted Delivery to EGF Receptor-Overexpressing Tumor Cells

(2011) Shibin Ai et al.   MOLECULAR PHARMACEUTICS

A peptide-based material platform for displaying antibodies to engage T cells

(2010) Ying Zheng et al.   BIOMATERIALS

Antibody–drug conjugates for cancer: poised to deliver?

(2010) Bethan Hughes   NATURE REVIEWS DRUG DISCOVERY

Targeted Cancer Therapy: Conferring Specificity to Cytotoxic Drugs

(2007) Ravi V. J. Chari   ACCOUNTS OF CHEMICAL RESEARCH