The Role of Protein Arginine Methyltransferases in Inflammatory Responses

Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation

(2015) Jiawen Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2

(2015) Andrea Hadjikyriacou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 Expression in Fibroblasts and Chronic Antigen-Induced Pulmonary Inflammation

(2015) Qingzhu Sun et al.   JOURNAL OF IMMUNOLOGY

PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145

(2015) Yanzhong Yang et al.   Nature Communications

Oleanolic acid regulates NF-κB signaling by suppressing MafK expression in RAW 264.7 cells

(2014) Yu-Jin Hwang et al.   BMB Reports

Role of vascular smooth muscle cell in the inflammation of atherosclerosis

(2014) Soyeon Lim et al.   BMB Reports

Tumor Necrosis Factor (TNF)-α Induction of CXCL10 in Endothelial Cells Requires Protein Arginine Methyltransferase 5 (PRMT5)-mediated Nuclear Factor (NF)-κB p65 Methylation

(2014) Daniel P. Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator

(2014) Alessandra Di Lorenzo et al.   NUCLEIC ACIDS RESEARCH

Characterization of Proinflammatory Responses and Innate Signaling Activation in Macrophages Infected withMycobacterium scrofulaceum

(2014) Ki-Hye Kim et al.   Immune Network

Ursodeoxycholic Acid Ameliorates Pain Severity and Cartilage Degeneration in Monosodium Iodoacetate-Induced Osteoarthritis in Rats

(2014) Su-Jin Moon et al.   Immune Network

Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery

(2013) M. Bezzi et al.   GENES & DEVELOPMENT

PRMT5 dimethylates R30 of the p65 subunit to activate NF- B

(2013) H. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PRMT5 suppresses DR4-mediated CCL20 release via NF-κB pathway

(2012) DongSheng Wang et al.   CHINESE SCIENCE BULLETIN

Human Protein Arginine Methyltransferase 7 (PRMT7) Is a Type III Enzyme Forming ω-NG-Monomethylated Arginine Residues

(2012) Cecilia I. Zurita-Lopez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upregulated Protein Arginine Methyltransferase 1 by IL-4 Increases Eotaxin-1 Expression in Airway Epithelial Cells and Participates in Antigen-Induced Pulmonary Inflammation in Rats

(2012) Q. Sun et al.   JOURNAL OF IMMUNOLOGY

HOXA9 Methylation by PRMT5 Is Essential for Endothelial Cell Expression of Leukocyte Adhesion Molecules

(2012) S. Bandyopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor

(2012) Mathieu Neault et al.   NUCLEIC ACIDS RESEARCH

MAPK Signaling Drives Inflammation in LPS-Stimulated Cardiomyocytes: The Route of Crosstalk to G-Protein-Coupled Receptors

(2012) W. Joshua Frazier et al.   PLoS One

A Protein ArginineN-Methyltransferase 1 (PRMT1) and 2 Heteromeric Interaction Increases PRMT1 Enzymatic Activity

(2011) Magnolia L. Pak et al.   BIOCHEMISTRY

JAK2V617F-Mediated Phosphorylation of PRMT5 Downregulates Its Methyltransferase Activity and Promotes Myeloproliferation

(2011) Fan Liu et al.   CANCER CELL

The Exon Junction Complex Component Y14 Modulates the Activity of the Methylosome in Biogenesis of Spliceosomal Small Nuclear Ribonucleoproteins

(2011) Tzu-Wei Chuang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency

(2010) W.-W. Tee et al.   GENES & DEVELOPMENT

O-GlcNAc Transferase Regulates Mitotic Chromatin Dynamics

(2010) Kaoru Sakabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative Feedback Regulation of NF- B Action by CITED2 in the Nucleus

(2010) X. Lou et al.   JOURNAL OF IMMUNOLOGY

Automethylation of CARM1 allows coupling of transcription and mRNA splicing

(2010) Peter Kuhn et al.   NUCLEIC ACIDS RESEARCH

Protein arginine methyltransferase 6 regulates multiple aspects of gene expression

(2010) Matthew J. Harrison et al.   NUCLEIC ACIDS RESEARCH

Cited2 Is an Essential Regulator of Adult Hematopoietic Stem Cells

(2009) Kamil R. Kranc et al.   Cell Stem Cell

PRMT1-mediated arginine methylation of PIAS1 regulates STAT1 signaling

(2009) S. Weber et al.   GENES & DEVELOPMENT

Enzymatic Activity Is Required for thein VivoFunctions of CARM1

(2009) Daehoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical Control of CARM1 Enzymatic Activity by Phosphorylation

(2009) Qin Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mouse PRMT1 Null Allele Defines an Essential Role for Arginine Methylation in Genome Maintenance and Cell Proliferation

(2009) Z. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

PRMT5, a Novel TRAIL Receptor-Binding Protein, Inhibits TRAIL-Induced Apoptosis via Nuclear Factor- B Activation

(2009) H. Tanaka et al.   MOLECULAR CANCER RESEARCH

GANP suppresses the arginine methyltransferase PRMT5 regulating IL-4-mediated STAT6-signaling to IgE production in B cells

(2009) Hideya Igarashi et al.   MOLECULAR IMMUNOLOGY

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing

(2009) Quan Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5

(2008) Matthieu Lacroix et al.   EMBO REPORTS

PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function

(2008) Laure Jobert et al.   EXPERIMENTAL CELL RESEARCH

O-Linked β-N-Acetylglucosaminyltransferase Substrate Specificity Is Regulated by Myosin Phosphatase Targeting and Other Interacting Proteins

(2008) Win D. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Arginine Methyltransferase 1 Coactivates NF-κB-Dependent Gene Expression Synergistically with CARM1 and PARP1

(2008) Paul O. Hassa et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein Arginine Methyltransferase 5 Suppresses the Transcription of the RB Family of Tumor Suppressors in Leukemia and Lymphoma Cells

(2008) L. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Estrogen Rapid Signaling through Arginine Methylation by PRMT1

(2008) Muriel Le Romancer et al.   MOLECULAR CELL

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL

A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3

(2008) Na-zi Lei et al.   NUCLEIC ACIDS RESEARCH

The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation

(2008) Markus A. Kleinschmidt et al.   NUCLEIC ACIDS RESEARCH