Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ12,14-Prostaglandin J2(15d-PGJ2) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4+CD25−FOXP3+Cells

Ciglitazone, a Peroxisome Proliferator-Activated Receptor Gamma Ligand, Inhibits Proliferation and Differentiation of Th17 Cells

(2015) Dong Hyeok Kim et al.   Biomolecules & Therapeutics

The IL-23–IL-17 axis in inflammatory arthritis

(2015) Erik Lubberts   Nature Reviews Rheumatology

Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis

(2015) Raphael Sanches Peres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleosides Present on Phlebotomine Saliva Induce Immunossuppression and Promote the Infection Establishment

(2015) Vanessa Carregaro et al.   PLoS Neglected Tropical Diseases

PPAR- /IL-10 Axis Inhibits MyD88 Expression and Ameliorates Murine Polymicrobial Sepsis

(2014) A. E. Ferreira et al.   JOURNAL OF IMMUNOLOGY

The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Preserves Bone Microarchitecture in Experimental Arthritis by Reducing the Interleukin-17-Dependent Osteoclastogenic Pathway

(2013) Meriem Koufany et al.   ARTHRITIS AND RHEUMATISM

Exogenous Administration of 15d-PGJ2-Loaded Nanocapsules Inhibits Bone Resorption in a Mouse Periodontitis Model

(2012) M. H. Napimoga et al.   JOURNAL OF IMMUNOLOGY

Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: Rationale for combination treatment during arthritis

(2011) Marije I. Koenders et al.   ARTHRITIS AND RHEUMATISM

PPAR-γ agonists, mainly 15d-PGJ2, reduce eosinophil recruitment following allergen challenge

(2011) Thais S. Farnesi-de-Assunção et al.   CELLULAR IMMUNOLOGY

Modulation of inflammatory response and parasitism by 15-Deoxy-Δ12,14 prostaglandin J2 in Trypanosoma cruzi-infected cardiomyocytes

(2011) Eugenia Hovsepian et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Nucleosides from Phlebotomus papatasi Salivary Gland Ameliorate Murine Collagen-Induced Arthritis by Impairing Dendritic Cell Functions

(2011) Vanessa Carregaro et al.   JOURNAL OF IMMUNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Peroxisome Proliferator-Activated Receptor   and   Agonists Together with TGF-  Convert Human CD4+CD25- T Cells into Functional Foxp3+ Regulatory T Cells

(2010) J. Lei et al.   JOURNAL OF IMMUNOLOGY

Peroxisome proliferator-activated receptor gamma in osteoarthritis

(2010) Hassan Fahmi et al.   Modern Rheumatology

15-DEOXY-Δ12,14 PROSTAGLANDIN GJ2 BUT NOT ROSIGLITAZONE REGULATES METALLOPROTEINASE 9, NOS-2, AND CYCLOOXYGENASE 2 EXPRESSION AND FUNCTIONS BY PEROXISOME PROLIFERATORYACTIVATED RECEPTOR γ-DEPENDENT AND -INDEPENDENT MECHANISMS IN CARDIAC CELLS

(2010) Eugenia Hovsepian et al.   SHOCK

Transcriptional Regulation of T Helper 17 Cell Differentiation

(2010) Eun Sook Hwang   YONSEI MEDICAL JOURNAL

Purified Eicosapentaenoic Acid Induces Prolonged Survival of Cardiac Allografts and Generates Regulatory T Cells

(2009) D. Iwami et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

(2009) Luisa Klotz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peroxisome Proliferator-Activated Receptor   Agonist Down-Regulates IL-17 Expression in a Murine Model of Allergic Airway Inflammation

(2009) S. J. Park et al.   JOURNAL OF IMMUNOLOGY

IL-17 mediates articular hypernociception in antigen-induced arthritis in mice

(2009) Larissa G. Pinto et al.   PAIN

IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?

(2007) Erik Lubberts   CYTOKINE