Slc12a2 loss in insulin-secreting β-cells links development of overweight and metabolic dysregulation to impaired satiation control of feeding

The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent

(2023) Karla J Suchacki et al.   eLife

The energy balance hypothesis of obesity: do the laws of thermodynamics explain excessive adiposity?

(2022) Vicente Torres-Carot et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Loss of Slc12a2 specifically in pancreatic β-cells drives metabolic syndrome in mice

(2022) Rana Abdelgawad et al.   PLoS One

Insulin Resistance and Hyperinsulinemia: the Egg and the Chicken

(2021) Muhammad Abdul-Ghani et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The feeding microstructure of male and female mice

(2021) Yakshkumar Dilipbhai Rathod et al.   PLoS One

Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance

(2021) Garron T. Dodd et al.   Science Advances

Diet-induced obesity in animal models: points to consider and influence on metabolic markers

(2021) Mariana de Moura e Dias et al.   Diabetology & Metabolic Syndrome

Chewing increases postprandial diet-induced thermogenesis

(2021) Yuka Hamada et al.   Scientific Reports

Very Low and Higher Carbohydrate Diets Promote Differential Appetite Responses in Adults with Type 2 Diabetes: A Randomized Trial

(2020) Noor A Struik et al.   JOURNAL OF NUTRITION

Central nervous pathways of insulin action in the control of metabolism and food intake

(2020) Stephanie Kullmann et al.   Lancet Diabetes & Endocrinology

Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet

(2020) Mauricio Di Fulvio et al.   PLoS One

Associations of prenatal exposure to impaired glucose tolerance with eating in the absence of hunger in early adolescence

(2019) Ivonne P. M. Derks et al.   INTERNATIONAL JOURNAL OF OBESITY

Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects

(2019) Mathias Rask-Andersen et al.   Nature Communications

The FATZO mouse, a next generation model of type 2 diabetes, develops NAFLD and NASH when fed a Western diet supplemented with fructose

(2019) Gao Sun et al.   BMC GASTROENTEROLOGY

Impaired glucose tolerance, glucagon and insulin responses in mice lacking the loop diuretic-sensitive Nkcc2a

(2019) Lisa Kelly et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

β Cell dysfunction during progression of metabolic syndrome to type 2 diabetes

(2019) Laura I. Hudish et al.   JOURNAL OF CLINICAL INVESTIGATION

Chloride transporters and channels in β-cell physiology: revisiting a 40-year-old model

(2019) Mauricio Di Fulvio et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The homeostatic dynamics of feeding behaviour identify novel mechanisms of anorectic agents

(2019) Thomas M. McGrath et al.   PLOS BIOLOGY

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Estradiol and the control of feeding behavior

(2018) H.M. Rivera et al.   STEROIDS

Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice

(2018) Yun Teng et al.   Nutrients

High Dose Diazoxide-mediated Insulin Suppression boosts Weight Loss induced by Lifestyle Intervention

(2018) Sandra Loves et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genome-Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex-Specific Adiposity Loci in Mexican Americans

(2017) Chuan Gao et al.   Obesity

Ghrelin, CCK, GLP-1, and PYY(3–36): Secretory Controls and Physiological Roles in Eating and Glycemia in Health, Obesity, and After RYGB

(2017) Robert E. Steinert et al.   PHYSIOLOGICAL REVIEWS

Correlation of disease severity with body weight and high fat diet in the FATZO/Pco mouse

(2017) Brian A. Droz et al.   PLoS One

Glucose dysregulation and response to common anti-diabetic agents in the FATZO/Pco mouse

(2017) Richard G. Peterson et al.   PLoS One

Corrigendum to “Insulin controls food intake and energy balance via NPY neurons” [Mol Metabol 6 (2017) 574–584]

(2017) Kim Loh et al.   Molecular Metabolism

A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice

(2016) Camille Attané et al.   DIABETOLOGIA

Changes in Leptin Signaling by SOCS3 Modulate Fasting-Induced Hyperphagia and Weight Regain in Mice

(2016) João A. B. Pedroso et al.   ENDOCRINOLOGY

Caloric restriction of db/db mice reverts hepatic steatosis and body weight with divergent hepatic metabolism

(2016) Kyung Eun Kim et al.   Scientific Reports

Pharmacological Inhibition of PI3K Reduces Adiposity and Metabolic Syndrome in Obese Mice and Rhesus Monkeys

(2015) Ana Ortega-Molina et al.   Cell Metabolism

Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity

(2015) Nicole M. Templeman et al.   DIABETOLOGIA

Association between eating rate and obesity: a systematic review and meta-analysis

(2015) T Ohkuma et al.   INTERNATIONAL JOURNAL OF OBESITY

Ins1 Cre knock-in mice for beta cell-specific gene recombination

(2014) Bernard Thorens et al.   DIABETOLOGIA

Ghrelin Receptor Regulates Appetite and Satiety during Aging in Mice by Regulating Meal Frequency and Portion Size but Not Total Food Intake

(2014) Ligen Lin et al.   JOURNAL OF NUTRITION

The number of chews and meal duration affect diet-induced thermogenesis and splanchnic circulation

(2014) Yuka Hamada et al.   Obesity

Variety, Palatability, and Obesity

(2014) Fiona Johnson et al.   Advances in Nutrition

Portion Size and Obesity

(2014) M. Barbara E. Livingstone et al.   Advances in Nutrition

Single nucleotide polymorphisms and haplotypes associated with feed efficiency in beef cattle

(2013) Nick VL Serão et al.   BMC GENETICS

Identification of genes regulating growth and fatness traits in pig through hypothalamic transcriptome analysis

(2013) Dafne Pérez-Montarelo et al.   PHYSIOLOGICAL GENOMICS

Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Production

(2012) Arya E. Mehran et al.   Cell Metabolism

Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity

(2012) Ana Ortega-Molina et al.   Cell Metabolism

Postprandial Administration of Intranasal Insulin Intensifies Satiety and Reduces Intake of Palatable Snacks in Women

(2012) M. Hallschmid et al.   DIABETES

Diabetes: Have We Got It All Wrong?: Insulin hypersecretion and food additives: cause of obesity and diabetes?

(2012) B. E. Corkey   DIABETES CARE

Disordered insulin secretion in the development of insulin resistance and Type 2 diabetes

(2012) C. J. Schofield et al.   DIABETIC MEDICINE

Over-Expression of Leptin Receptors in Hypothalamic POMC Neurons Increases Susceptibility to Diet-Induced Obesity

(2012) Kevin M. Gamber et al.   PLoS One

Selection Signature Analysis Implicates the PC1/PCSK1 Region for Chicken Abdominal Fat Content

(2012) Hui Zhang et al.   PLoS One

Impaired Satiation and Increased Feeding Behaviour in the Triple-Transgenic Alzheimer's Disease Mouse Model

(2012) Adedolapo Adebakin et al.   PLoS One

Retrospective longitudinal study on the relationship between 8-year weight change and current eating speed

(2011) Shinichi Tanihara et al.   APPETITE

Global gene expression profiling reveals genes expressed differentially in cattle with high and low residual feed intake

(2011) Y. Chen et al.   ANIMAL GENETICS

Banting Lecture 2011: Hyperinsulinemia: Cause or Consequence?

(2011) B. E. Corkey   DIABETES

Insulin Resistance: the Link Between Obesity and Cardiovascular Disease

(2011) Gerald M. Reaven   MEDICAL CLINICS OF NORTH AMERICA

Direct Insulin and Leptin Action on Pro-opiomelanocortin Neurons Is Required for Normal Glucose Homeostasis and Fertility

(2010) Jennifer W. Hill et al.   Cell Metabolism

NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse

(2009) Owen P. McGuinness et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Leptin-Dependent Control of Glucose Balance and Locomotor Activity by POMC Neurons

(2009) Lihong Huo et al.   Cell Metabolism

Enhanced Stat3 Activation in POMC Neurons Provokes Negative Feedback Inhibition of Leptin and InsulinSignaling in Obesity

(2009) M. B. Ernst et al.   JOURNAL OF NEUROSCIENCE

The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

(2009) Leona Plum et al.   NATURE MEDICINE

Development of Obesity is Associated with Increased Calories per Meal Rather than per Day. A Study of High-Fat Diet-Induced Obesity in Young Rats

(2009) Marianne W. Furnes et al.   OBESITY SURGERY

Effects of estradiol on food intake and meal patterns for diets that differ in flavor and fat content

(2009) Peter C. Butera et al.   PHYSIOLOGY & BEHAVIOR

Eating patterns and portion size associated with obesity in a Swedish population

(2008) Christina Berg et al.   APPETITE

PDK1 Deficiency in POMC-Expressing Cells Reveals FOXO1-Dependent and -Independent Pathways in Control of Energy Homeostasis and Stress Response

(2008) Bengt F. Belgardt et al.   Cell Metabolism

Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats

(2008) Ramin Alemzadeh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL