RIP1/3-dependent programmed necrosis induces intestinal injury in septic rats

Ketamine inhibits TNF-α-induced cecal damage by enhancing RIP1 ubiquitination to attenuate lethal SIRS

(2022) Bin Deng et al.   Cell Death Discovery

Investigation of oxidant/antioxidant and anti‐inflammatory effects of apigenin on apoptosis in sepsis‐induced rat lung

(2021) Mustafa Cicek et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

RIP1-Mediated Necroptosis Facilitates Oxidative Stress‒Induced Melanocyte Death, Offering Insight into Vitiligo

(2021) Bowei Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

MiR‐195‐5p represses inflammation, apoptosis, oxidative stress, and endoplasmic reticulum stress in sepsis‐induced myocardial injury by targeting activating transcription factor 6

(2021) Hongxia Xia et al.   CELL BIOLOGY INTERNATIONAL

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

(2021) Laura Evans et al.   INTENSIVE CARE MEDICINE

miR-425-5p improves inflammation and septic liver damage through negatively regulating the RIP1-mediated necroptosis

(2020) Changwei Gu et al.   INFLAMMATION RESEARCH

Emerging connectivity of programmed cell death pathways and its physiological implications

(2020) Sammy Bedoui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Necrostatin-1 accelerates time to death in a rat model of cecal ligation and puncture and massively increases hepatocyte caspase-3 cleavage

(2019) Qin Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex

(2018) Miguel Mompeán et al.   CELL

RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells

(2018) Mark A. Hawk et al.   NATURE CELL BIOLOGY

RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis

(2018) Zhentao Yang et al.   NATURE CELL BIOLOGY

Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death

(2015) B Schenk et al.   ONCOGENE

RIPK1 and RIPK3: critical regulators of inflammation and cell death

(2015) Kim Newton   TRENDS IN CELL BIOLOGY

Insulin alleviates the inflammatory response and oxidative stress injury in cerebral tissues in septic rats

(2014) Qiyi Chen et al.   Journal of Inflammation-London

Necroptosis Mediates TNF-Induced Toxicity of Hippocampal Neurons

(2014) Shan Liu et al.   Biomed Research International

Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia–reperfusion in vivo

(2012) Martinus I. F. J. Oerlemans et al.   BASIC RESEARCH IN CARDIOLOGY

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

(2012) Zhigao Wang et al.   CELL

The Dual Functions of Receptor Interacting Protein 1 in Fas-Induced Hepatocyte Death During Sepsis

(2011) Sam I. McNeal et al.   SHOCK

Hypoxia influences linearly patterned programmed cell necrosis and tumor blood supply patterns formation in melanoma

(2009) Shiwu Zhang et al.   LABORATORY INVESTIGATION

Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis

(2008) Adrian M Piliponsky et al.   NATURE MEDICINE