Chemical Expansion of the Methyltransferase Reaction: Tools for DNA Labeling and Epigenome Analysis

Chemo-Enzymatic Modification of the 5′ Cap To Study mRNAs

(2022) Amarnath Bollu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Selective chemical tracking of Dnmt1 catalytic activity in live cells

(2022) Vaidotas Stankevičius et al.   MOLECULAR CELL

Enhanced nucleosome assembly at CpG sites containing an extended 5-methylcytosine analogue

(2022) Miglė Tomkuvienė et al.   NUCLEIC ACIDS RESEARCH

REBASE: a database for DNA restriction and modification: enzymes, genes and genomes

(2022) Richard J Roberts et al.   NUCLEIC ACIDS RESEARCH

Multiomics Analysis of Neuroblastoma Cells Reveals a Diversity of Malignant Transformations

(2021) Milda Narmontė et al.   Frontiers in Cell and Developmental Biology

Propargylic Se-adenosyl-l-selenomethionine: A Chemical Tool for Methylome Analysis

(2021) Yoshihiro Sohtome et al.   ACCOUNTS OF CHEMICAL RESEARCH

A metabolic labeling method detects m6A transcriptome-wide at single base resolution

(2020) Xiao Shu et al.   Nature Chemical Biology

Site-Selective and Rewritable Labeling of DNA through Enzymatic, Reversible, and Click Chemistries

(2020) Andrew A. Wilkinson et al.   ACS Central Science

Long-read human genome sequencing and its applications

(2020) Glennis A. Logsdon et al.   NATURE REVIEWS GENETICS

Identification of fetal unmodified and 5-hydroxymethylated CG sites in maternal cell-free DNA for non-invasive prenatal testing

(2020) Juozas Gordevičius et al.   Clinical Epigenetics

DNA barcodes for rapid, whole genome, single-molecule analyses

(2019) Nathaniel O Wand et al.   NUCLEIC ACIDS RESEARCH

Role of Mammalian DNA Methyltransferases in Development

(2019) Zhiyuan Chen et al.   Annual Review of Biochemistry

Enzymatic or In Vivo Installation of Propargyl Groups in Combination with Click Chemistry for the Enrichment and Detection of Methyltransferase Target Sites in RNA

(2018) Katja Hartstock et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural basis for DNMT3A-mediated de novo DNA methylation

(2018) Zhi-Min Zhang et al.   NATURE

Animal Hen1 2′-O-methyltransferases as tools for 3′-terminal functionalization and labelling of single-stranded RNAs

(2018) Milda Mickutė et al.   NUCLEIC ACIDS RESEARCH

A general strategy for direct, enzyme-catalyzed conjugation of functional compounds to DNA

(2018) Jochem Deen et al.   NUCLEIC ACIDS RESEARCH

A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping

(2018) Stéphane Deschamps et al.   Nature Communications

Tethered Oligonucleotide-Primed Sequencing, TOP-Seq: A High-Resolution Economical Approach for DNA Epigenome Profiling

(2017) Zdislav Staševskij et al.   MOLECULAR CELL

Bacteriophage strain typing by rapid single molecule analysis

(2015) Assaf Grunwald et al.   NUCLEIC ACIDS RESEARCH

Facile Chemoenzymatic Strategies for the Synthesis and Utilization ofS-Adenosyl-L-Methionine Analogues

(2014) Shanteri Singh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells

(2014) Nobuaki Shiraki et al.   Cell Metabolism

Selective Covalent Labeling of miRNA and siRNA Duplexes Using HEN1 Methyltransferase

(2014) Alexandra Plotnikova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhanced Chemical Stability of AdoMet Analogues for Improved Methyltransferase-Directed Labeling of DNA

(2013) Gražvydas Lukinavičius et al.   ACS Chemical Biology

A Chemo-Enzymatic Approach for Site-Specific Modification of the RNA Cap

(2013) Daniela Schulz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA unmethylome profiling by covalent capture of CpG sites

(2013) Edita Kriukienė et al.   Nature Communications

A Selenium-Based Click AdoMet Analogue for Versatile Substrate Labeling with Wild-Type Protein Methyltransferases

(2012) Sophie Willnow et al.   CHEMBIOCHEM

Se-Adenosyl-l-selenomethionine Cofactor Analogue as a Reporter of Protein Methylation

(2012) Ian R. Bothwell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Profiling Genome-Wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells

(2012) Rui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering the DNA cytosine-5 methyltransferase reaction for sequence-specific labeling of DNA

(2012) Gražvydas Lukinavičius et al.   NUCLEIC ACIDS RESEARCH

Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases

(2012) Miglė Tomkuvienė et al.   NUCLEIC ACIDS RESEARCH

Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

(2012) J. Song et al.   SCIENCE

Direct observation of cytosine flipping and covalent catalysis in a DNA methyltransferase

(2011) Rūta Gerasimaitė et al.   NUCLEIC ACIDS RESEARCH

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

(2011) K. Takeshita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzyme-Catalyzed Transfer of a Ketone Group from anS-Adenosylmethionine Analogue: A Tool for the Functional Analysis of Methyltransferases

(2010) Bobby W.K. Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA fluorocode: A single molecule, optical map of DNA with nanometre resolution

(2010) Robert K. Neely et al.   Chemical Science

Biocatalytic Friedel-Crafts Alkylation Using Non-natural Cofactors

(2009) Harald Stecher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION