Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A Journey from Weird to Wondrous

SUMOylation in Viral Replication and Antiviral Defense

(2022) Yao Fan et al.   Advanced Science

ADAR RNA Modifications, the Epitranscriptome and Innate Immunity

(2021) Jaclyn Quin et al.   TRENDS IN BIOCHEMICAL SCIENCES

MODOMICS: a database of RNA modification pathways. 2021 update

(2021) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

(2020) Anzer Khan et al.   BMC BIOLOGY

Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures

(2020) Tiong Yang Tan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

(2020) Patricia Deng et al.   Nature Communications

Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy

(2020) Reza Maroofian et al.   JOURNAL OF MEDICAL GENETICS

Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition

(2020) Alexander S Thuy-Boun et al.   NUCLEIC ACIDS RESEARCH

ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility

(2020) Elizabeth Snyder et al.   Scientific Reports

Dyschromatosis symmetrica hereditaria and reticulate acropigmentation of Kitamura: an update

(2019) Michihiro Kono et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Methods for RNA Modification Mapping Using Deep Sequencing: Established and New Emerging Technologies

(2019) Yuri Motorin et al.   Genes

A resource for selecting animal models of heart disease

(2019) Alexandra Le Bras   LAB ANIMAL

RNA editing of Filamin A pre‐mRNA regulates vascular contraction and diastolic blood pressure

(2018) Mamta Jain et al.   EMBO JOURNAL

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

(2018) Jeffrey J. Ishizuka et al.   NATURE

Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

(2018) Huayang Liu et al.   NATURE MEDICINE

Inosine induces context-dependent recoding and translational stalling

(2018) Konstantin Licht et al.   NUCLEIC ACIDS RESEARCH

Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development

(2017) Mikaela Behm et al.   JOURNAL OF CELL SCIENCE

Dynamic landscape and regulation of RNA editing in mammals

(2017) Meng How Tan et al.   NATURE

ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity

(2016) J. E. Robinson et al.   Nature Communications

Alu element-containing RNAs maintain nucleolar structure and function

(2015) M. Caudron-Herger et al.   EMBO JOURNAL

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

(2013) L. Bazak et al.   GENOME RESEARCH

A type I interferon signature identifies bilateral striatal necrosis due to mutations inADAR1

(2013) John H Livingston et al.   JOURNAL OF MEDICAL GENETICS

The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster

(2013) X. Li et al.   NUCLEIC ACIDS RESEARCH

Adar is essential for optimal presynaptic function

(2012) Carolina Maldonado et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Pin1 and WWP2 regulateGluR2Q/R site RNA editing by ADAR2 with opposing effects

(2011) Roberto Marcucci et al.   EMBO JOURNAL

Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects

(2011) Liam P. Keegan et al.   NUCLEIC ACIDS RESEARCH

The developmental transcriptome of Drosophila melanogaster

(2010) Brenton R. Graveley et al.   NATURE

Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis

(2010) Patrice Vitali et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Editing independent effects of ADARs on the miRNA/siRNA pathways

(2009) Bret S E Heale et al.   EMBO JOURNAL

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

(2009) Gillian I Rice et al.   NATURE GENETICS

Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR

(2009) Roberto Marcucci et al.   NUCLEIC ACIDS RESEARCH