Development and Evaluation of Amorphous Solid Dispersion of Riluzole with PBPK Model to Simulate the Pharmacokinetic Profile
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Development and Evaluation of Amorphous Solid Dispersion of Riluzole with PBPK Model to Simulate the Pharmacokinetic Profile
Authors
Keywords
-
Journal
AAPS PHARMSCITECH
Volume 24, Issue 8, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-28
DOI
10.1208/s12249-023-02680-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Co-Crystallization Approach to Enhance the Stability of Moisture-Sensitive Drugs
- (2023) Madhukiran R. Dhondale et al. Pharmaceutics
- The Role of “Physiologically Based Pharmacokinetic Model (PBPK)” New Approach Methodology (NAM) in Pharmaceuticals and Environmental Chemical Risk Assessment
- (2023) Deepika Deepika et al. International Journal of Environmental Research and Public Health
- Unusual Correlation between the Apparent Amorphous Solubility of a Drug and Solubilizer Concentration Revealed by NMR Analysis
- (2022) Keisuke Ueda et al. MOLECULAR PHARMACEUTICS
- Surface Characterization as a Tool for Identifying the Factors Affecting the Dissolution Rate of Amorphous Solid Dispersion Tablets
- (2022) Dongyue Yu et al. AAPS PHARMSCITECH
- Role of surfactants in improving release from higher drug loading amorphous solid dispersions
- (2022) Clara E. Correa-Soto et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Release mechanisms of amorphous solid dispersions: Role of drug-polymer phase separation and morphology
- (2022) Ruochen Yang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime
- (2021) Deepika Deepika et al. ENVIRONMENTAL RESEARCH
- Characterization of Amorphous Solid Dispersions and Identification of Low Levels of Crystallinity by Transmission Electron Microscopy
- (2021) Mark S’ari et al. MOLECULAR PHARMACEUTICS
- Paraquat pharmacokinetics in primates and extrapolation to humans
- (2021) Alexander J. Stevens et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
- (2021) Sonal V. Bhujbal et al. Acta Pharmaceutica Sinica B
- Assessing Effects of BHV-0223 40 mg Zydis Sublingual Formulation and Riluzole 50 mg Oral Tablet on Liver Function Test Parameters Utilizing DILIsym
- (2020) Diane M Longo et al. TOXICOLOGICAL SCIENCES
- Quantification of the Impact of Partition Coefficient Prediction Methods on PBPK Model Output Using a Standardized Tissue Composition
- (2020) Kiersten Utsey et al. DRUG METABOLISM AND DISPOSITION
- Patterns of drug release as a function of drug loading from amorphous solid dispersions: A comparison of five different polymers.
- (2020) Sugandha Saboo et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- The Influence of the Strength of Drug–Polymer Interactions on the Dissolution of Amorphous Solid Dispersions
- (2020) Kweku K. Amponsah-Efah et al. MOLECULAR PHARMACEUTICS
- Insights into the Dissolution Mechanism of Ritonavir–Copovidone Amorphous Solid Dispersions: Importance of Congruent Release for Enhanced Performance
- (2019) Anura S. Indulkar et al. MOLECULAR PHARMACEUTICS
- Congruent release of drug and polymer: A “sweet spot” in the dissolution of amorphous solid dispersions
- (2019) Sugandha Saboo et al. JOURNAL OF CONTROLLED RELEASE
- Assessment of Biopharmaceutical Performance of Supersaturating Formulations of Carbamazepine in Rats Using Physiologically Based Pharmacokinetic Modeling
- (2019) Samarth D. Thakore et al. AAPS PHARMSCITECH
- Interpretation of Non-Clinical Data for Prediction of Human Pharmacokinetic Parameters: In Vitro-In Vivo Extrapolation and Allometric Scaling
- (2019) Go-Wun Choi et al. Pharmaceutics
- Development and evaluation of a harmonized whole body physiologically based pharmacokinetic (PBPK) model for flutamide in rats and its extrapolation to humans
- (2019) Raju Prasad Sharma et al. ENVIRONMENTAL RESEARCH
- Two Decades-Long Journey from Riluzole to Edaravone: Revisiting the Clinical Pharmacokinetics of the Only Two Amyotrophic Lateral Sclerosis Therapeutics
- (2018) Ranjeet Prasad Dash et al. CLINICAL PHARMACOKINETICS
- Understanding the generation and maintenance of supersaturation during the dissolution of amorphous solid dispersions using modulated DSC and 1 H NMR
- (2018) Shrawan Baghel et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation
- (2018) Hitesh S. Purohit et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Riluzole, disease stage and survival in ALS
- (2018) Thanuja Dharmadasa et al. LANCET NEUROLOGY
- Influence of Drug–Polymer Interactions on Dissolution of Thermodynamically Highly Unstable Cocrystal
- (2018) Milankumar S. Jasani et al. MOLECULAR PHARMACEUTICS
- The effect of surfactants on the dissolution behavior of amorphous formulations
- (2016) Pei T. Mah et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- PBPK Model for Atrazine and Its Chlorotriazine Metabolites in Rat and Human
- (2016) Jerry L. Campbell et al. TOXICOLOGICAL SCIENCES
- Role of the Strength of Drug–Polymer Interactions on the Molecular Mobility and Crystallization Inhibition in Ketoconazole Solid Dispersions
- (2015) Pinal Mistry et al. MOLECULAR PHARMACEUTICS
- Riluzole for the treatment of acute traumatic spinal cord injury: rationale for and design of the NACTN Phase I clinical trial
- (2015) Michael G. Fehlings et al. JOURNAL OF NEUROSURGERY-SPINE
- A physiologically based pharmacokinetic model of alvespimycin in mice and extrapolation to rats and humans
- (2014) Zhe-Yi Hu et al. BRITISH JOURNAL OF PHARMACOLOGY
- The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: A meta-analysis
- (2014) Yun-Jian Sheng et al. INFECTION GENETICS AND EVOLUTION
- Curcumin and its nano-formulation: The kinetics of tissue distribution and blood–brain barrier penetration
- (2011) Yin-Meng Tsai et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human
- (2011) Dhaval K. Shah et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- Quantitative estimation of riluzole in human plasma by LC-ESI-MS/MS and its application to a bioequivalence study
- (2010) Babu Rao Chandu et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Evaluation and prediction of pharmacokinetics of PFOA and PFOS in the monkey and human using a PBPK model
- (2010) Anne E. Loccisano et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?
- (2009) Joachim Brouwers et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effect of temperature and moisture on the miscibility of amorphous dispersions of felodipine and poly(vinyl pyrrolidone)
- (2009) Patrick J. Marsac et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A physiologically based pharmacokinetic model for developmental exposure to BDE-47 in rats
- (2009) Claude Emond et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started