A systematic approach to diverse, lead-like scaffolds from α,α-disubstituted amino acids

A unified lead-oriented synthesis of over fifty molecular scaffolds

(2015) Richard G. Doveston et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A modular lead-oriented synthesis of diverse piperazine, 1,4-diazepane and 1,5-diazocane scaffolds

(2014) Thomas James et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Toward Lead-Oriented Synthesis: One-Pot Version of Castagnoli Condensation with Nonactivated Alicyclic Anhydrides

(2014) Sergey V. Ryabukhin et al.   ACS Combinatorial Science

A conceptual framework for analysing and planning synthetic approaches to diverse lead-like scaffolds

(2013) Paul MacLellan et al.   CHEMICAL COMMUNICATIONS

Towards the realisation of lead-oriented synthesis

(2013) Richard Doveston et al.   DRUG DISCOVERY TODAY

Modular, Gold-Catalyzed Approach to the Synthesis of Lead-like Piperazine Scaffolds

(2013) Thomas James et al.   ORGANIC LETTERS

Lead-Oriented Synthesis: A New Opportunity for Synthetic Chemistry

(2012) Alan Nadin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ZINC: A Free Tool to Discover Chemistry for Biology

(2012) John J. Irwin et al.   Journal of Chemical Information and Modeling

Recent Developments in Methodology for the Direct Oxyamination of Olefins

(2010) Timothy J. Donohoe et al.   CHEMISTRY-A EUROPEAN JOURNAL

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

The influence of lead discovery strategies on the properties of drug candidates

(2009) György M. Keserü et al.   NATURE REVIEWS DRUG DISCOVERY

Structural Diversity of Organic Chemistry. A Scaffold Analysis of the CAS Registry

(2008) Alan H. Lipkus et al.   JOURNAL OF ORGANIC CHEMISTRY