Novel Selective Inhibitor ofLeishmania (Leishmania) amazonensisArginase

Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections

(2013) Edward L. D’Antonio et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection

(2013) Leticia Correa Manjolin et al.   FOOD CHEMISTRY

Inhibition of Leishmania (Leishmania) amazonensis and Rat Arginases by Green Tea EGCG, (+)-Catechin and (−)-Epicatechin: A Comparative Structural Analysis of Enzyme-Inhibitor Interactions

(2013) Matheus Balduíno Goncalves dos Reis et al.   PLoS One

The leishmanicidal flavonols quercetin and quercitrin target Leishmania (Leishmania) amazonensis arginase

(2012) Edson Roberto da Silva et al.   EXPERIMENTAL PARASITOLOGY

New Trifluoromethyl Triazolopyrimidines as Anti-Plasmodium falciparum Agents

(2012) Núbia Boechat et al.   MOLECULES

Leishmania amazonensis Arginase Compartmentalization in the Glycosome Is Important for Parasite Infectivity

(2012) Maria Fernanda Laranjeira da Silva et al.   PLoS One

Anti-leishmanial activity of disubstituted purines and related pyrazolo[4,3-d]pyrimidines

(2011) Radek Jorda et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I

(2011) Eric Riley et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Axenic Leishmania amazonensis Promastigotes Sense both the External and Internal Arginine Pool Distinctly Regulating the Two Transporter-Coding Genes

(2011) Emerson A. Castilho-Martins et al.   PLoS One

Polyamine metabolism in Leishmania: from arginine to trypanothione

(2010) Gianni Colotti et al.   AMINO ACIDS

Synthesis and biological evaluation of indolyl glyoxylamides as a new class of antileishmanial agents

(2010) Shikha S. Chauhan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity

(2009) Stefano Guglielmo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Trypanothione efficiently intercepts nitric oxide as a harmless iron complex in trypanosomatid parasites

(2009) Alessio Bocedi et al.   FASEB JOURNAL

Structure−Activity Relationship and Studies on the Molecular Mechanism of LeishmanicidalN,C-Coupled Arylisoquinolinium Salts

(2009) Alicia Ponte-Sucre et al.   JOURNAL OF MEDICINAL CHEMISTRY

Leishmania major lacking arginase (ARG) are auxotrophic for polyamines but retain infectivity to susceptible BALB/c mice

(2009) Rosa M. Reguera et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

New Treatment Approach in Indian Visceral Leishmaniasis: Single‐Dose Liposomal Amphotericin B Followed by Short‐Course Oral Miltefosine

(2008) Shyam Sundar et al.   CLINICAL INFECTIOUS DISEASES

Treatment of leishmaniasis with miltefosine: 2008 status

(2008) Jonathan (Josh) Berman   Expert Opinion on Drug Metabolism & Toxicology

Biochemical and biophysical properties of a highly active recombinant arginase from Leishmania (Leishmania) amazonensis and subcellular localization of native enzyme

(2008) Edson Roberto da Silva et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY