Journal
MATERIALS LETTERS
Volume 164, Issue -, Pages 144-147Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2015.10.145
Keywords
Magnesium alloy; Biomaterials; Hydrothermal deposition; Bone tissue regeneration; Biomimetic
Funding
- Basic Science Research Program through the National Research Foundation of Korea (NRF)
- Ministry of Education, Science and Technology [2013R1A2A2A04015484]
- [NRF-2015R1C1A1A02036404]
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Third-generation biomaterials aim to stimulate specific cellular responses at the molecular level, these materials characterized with a resorbable and bioactivity that help body heal once they have been implanted. Here, a biomimetic method was used to generate hydroxyapatite (HA) nanoplates on the surface of AZ31B Mg alloy via anodization in simulated body fluid (SBF), followed by a hydrothermal (HT) process. The resulting nanoplates were characterized using FE-SEM, XRD, and FT-IR, surface hydrophobicity, in addition, corrosion was assessed electrochemically. The excellent bioactivity of the treated samples compared with naked ones were confirmed in vitro with MC3T3-E1 osteoblastic cells with significant growth and proliferation. (C) 2015 Elsevier B.V. All rights reserved.
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