Quinacrine Mediated Sensitization of Glioblastoma (GBM) Cells to TRAIL through MMP-Sensitive PEG Hydrogel Carriers

Identification of Mitoxantrone as a TRAIL-sensitizing agent for Glioblastoma Multiforme

(2016) Filiz Senbabaoglu et al.   CANCER BIOLOGY & THERAPY

Targeting cancer cells via tumor-homing peptide CREKA functional PEG nanoparticles

(2016) Aysu Ceren Okur et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Visible-light-induced synthesis of pH-responsive composite hydrogels for controlled delivery of the anticonvulsant drug pregabalin

(2015) Ozlem Cevik et al.   Acta Biomaterialia

Immunotherapy with liposome-bound TRAIL overcomes partial protection to soluble TRAIL-induced apoptosis offered by down-regulation of Bim in leukemic cells

(2015) D. De Miguel et al.   Clinical & Translational Oncology

Quinacrine induces apoptosis in human leukemia K562 cells via p38 MAPK-elicited BCL2 down-regulation and suppression of ERK/c-Jun-mediated BCL2L1 expression

(2015) Jung-Jung Changchien et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nanoparticle-Mediated Target Delivery of TRAIL as Gene Therapy for Glioblastoma

(2015) Kui Wang et al.   Advanced Healthcare Materials

Targeted delivery of doxorubicin into tumor cells via MMP-sensitive PEG hydrogel-coated magnetic iron oxide nanoparticles (MIONPs)

(2014) Caner Nazli et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Bioengineered 3D Brain Tumor Model To Elucidate the Effects of Matrix Stiffness on Glioblastoma Cell Behavior Using PEG-Based Hydrogels

(2014) Christine Wang et al.   MOLECULAR PHARMACEUTICS

Four-arm PEG cross-linked hyaluronic acid hydrogels containing PEGylated apoptotic TRAIL protein for treating pancreatic cancer

(2013) Hyeong Jun Byeon et al.   Acta Biomaterialia

Characterization of protein release from poly(ethylene glycol) hydrogels with crosslink density gradients

(2013) Tuğba Bal et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Sensitizing cancer cells to TRAIL-induced death by micellar delivery of mitoxantrone

(2013) Taraka Sai Pavan Grandhi et al.   Nanomedicine

Carnitine sensitizes TRAIL-resistant cancer cells to TRAIL-induced apoptotic cell death through the up-regulation of Bax

(2012) So Jung Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Specific VEGF sequestering and release using peptide-functionalized hydrogel microspheres

(2012) Nicholas A. Impellitteri et al.   BIOMATERIALS

BH3-only proteins in apoptosis at a glance

(2012) L. Happo et al.   JOURNAL OF CELL SCIENCE

Quantitative Mapping of the Elastic Modulus of Soft Materials with HarmoniX and PeakForce QNM AFM Modes

(2012) Maxim E. Dokukin et al.   LANGMUIR

Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors

(2012) T Bagci-Onder et al.   ONCOGENE

Quinacrine-Mediated Autophagy and Apoptosis in Colon Cancer Cells Is Through a p53- and p21-Dependent Mechanism

(2012) Purusottam Mohapatra et al.   ONCOLOGY RESEARCH

Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain

(2011) Sagar Agarwal et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Bio-inspired materials for parsing matrix physicochemical control of cell migration: A Review

(2011) Hyung-Do Kim et al.   Integrative Biology

Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity

(2011) Ranjan Preet et al.   INTERNATIONAL JOURNAL OF CANCER

Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor–related apoptosis-inducing ligand and induces an alternative cell death pathway

(2011) Christian E. Badr et al.   NEURO-ONCOLOGY

Facile formation of dynamic hydrogel microspheres for triggered growth factor delivery

(2010) William J. King et al.   Acta Biomaterialia

Biomimetic hydrogels with pro-angiogenic properties

(2010) James J. Moon et al.   BIOMATERIALS

Inhibition of NF-κB Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) or Oxaliplatin

(2010) Tanvi S. Jani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PEGylated TNF-related apoptosis-inducing ligand (TRAIL)-loaded sustained release PLGA microspheres for enhanced stability and antitumor activity

(2010) Tae Hyung Kim et al.   JOURNAL OF CONTROLLED RELEASE

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST)

(2010) A. Gupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversibly Stabilized Multifunctional Dextran Nanoparticles Efficiently Deliver Doxorubicin into the Nuclei of Cancer Cells

(2009) Yu-Ling Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

TRAILing death in cancer

(2009) Gregory Mellier et al.   MOLECULAR ASPECTS OF MEDICINE

Death receptor-4 (DR4) expression is regulated by transcription factor NF-κB in response to etoposide treatment

(2008) Francisco José Mendoza et al.   APOPTOSIS