Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity

Anti-malaria drug blocks proteotoxic stress response: Anti-cancer implications

(2011) Nickolay Neznanov et al.   CELL CYCLE

Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells

(2010) Kazuhito Sasaki et al.   BMC CANCER

Quinacrine Enhances Cisplatin-Induced Cytotoxicity in Four Cancer Cell Lines

(2010) Yixiang Wang et al.   CHEMOTHERAPY

Inhibition of NF-κB Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) or Oxaliplatin

(2010) Tanvi S. Jani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New hopes from old drugs: revisiting DNA-binding small molecules as anticancer agents

(2009) Katerina Gurova   Future Oncology

9-Aminoacridine-based anticancer drugs target the PI3K/AKT/mTOR, NF-κB and p53 pathways

(2009) C Guo et al.   ONCOGENE

Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II

(2008) Lisa M. Oppegard et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Acridine-Based Agents with Topoisomerase II Activity Inhibit Pancreatic Cancer Cell Proliferation and Induce Apoptosis

(2007) John R. Goodell et al.   JOURNAL OF MEDICINAL CHEMISTRY