Comparing domain interactions within antibody Fabs with kappa and lambda light chains

Protein design of IgG/TCR chimeras for the co-expression of Fab-like moieties within bispecific antibodies

(2015) Xiufeng Wu et al.   mAbs

Principles and engineering of antibody folding and assembly

(2014) Matthias J. Feige et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The therapeutic monoclonal antibody market

(2014) Dawn M Ecker et al.   mAbs

Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface

(2014) Steven M Lewis et al.   NATURE BIOTECHNOLOGY

Role of κ→λ light-chain constant-domain switch in the structure and functionality of A17 reactibody

(2014) Natalia Ponomarenko et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency

(2012) M Chodorge et al.   CELL DEATH AND DIFFERENTIATION

A Combination of Broadly Neutralizing HIV-1 Monoclonal Antibodies Targeting Distinct Epitopes Effectively Neutralizes Variants Found in Early Infection

(2012) L. Goo et al.   JOURNAL OF VIROLOGY

TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms

(2011) O. Y. Borbulevych et al.   JOURNAL OF IMMUNOLOGY

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

(2011) R. Pejchal et al.   SCIENCE

Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTβR

(2010) Jennifer S. Michaelson et al.   mAbs

Stability engineering of scFvs for the development of bispecific and multivalent antibodies

(2010) Brian R. Miller et al.   PROTEIN ENGINEERING DESIGN & SELECTION

An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies

(2009) Matthias J. Feige et al.   MOLECULAR CELL