A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency

Immune modulation with weekly dosing of an agonist CD40 antibody in a phase I study of patients with advanced solid tumors

(2011) Jens Rüter et al.   CANCER BIOLOGY & THERAPY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

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Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism

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APO010, a synthetic hexameric CD95 ligand, induces human glioma cell death in vitro and in vivo

(2010) G. Eisele et al.   NEURO-ONCOLOGY

Agonist Anti-GITR Monoclonal Antibody Induces Melanoma Tumor Immunity in Mice by Altering Regulatory T Cell Stability and Intra-Tumor Accumulation

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Clinical Experiences With Anti-CD137 and Anti-PD1 Therapeutic Antibodies

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Bistability in Apoptosis by Receptor Clustering

(2010) Kenneth L. Ho et al.   PLoS Computational Biology

The TNF superfamily in 2009: new pathways, new indications, and new drugs

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Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane

(2009) Patrick Lajoie et al.   JOURNAL OF CELL BIOLOGY

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

(2009) Fiona L. Scott et al.   NATURE

Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5

(2008) C Adams et al.   CELL DEATH AND DIFFERENTIATION

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

In vitro DNA recombination by L-Shuffling during ribosome display affinity maturation of an anti-Fas antibody increases the population of improved variants

(2008) Matthieu Chodorge et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens

(2008) C. Lloyd et al.   PROTEIN ENGINEERING DESIGN & SELECTION