Serum pharmacokinetics and cerebrospinal fluid concentration analysis of the new IgG4 monoclonal antibody GNbAC1 to treat multiple sclerosis: A Phase 1 study

Novel and imminently emerging treatments in relapsing–remitting multiple sclerosis

(2015) Jiwon Oh et al.   CURRENT OPINION IN NEUROLOGY

Monoclonal antibody therapy in multiple sclerosis: critical appraisal and new perspectives

(2015) Emanuele D’Amico et al.   Expert Review of Neurotherapeutics

A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients — A twelve month follow-up

(2015) Tobias Derfuss et al.   JOURNAL OF NEUROIMMUNOLOGY

Monoclonal antibody therapy in multiple sclerosis: critical appraisal and new perspectives

(2015) Emanuele D’Amico et al.   Expert Review of Neurotherapeutics

Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein

(2014) François Curtin et al.   mAbs

A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients

(2014) Tobias Derfuss et al.   Multiple Sclerosis Journal

Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation

(2013) David Kremer et al.   ANNALS OF NEUROLOGY

GNbAC1, a Humanized Monoclonal Antibody Against the Envelope Protein of Multiple Sclerosis—Associated Endogenous Retrovirus: A First-in-Humans Randomized Clinical Study

(2012) François Curtin et al.   CLINICAL THERAPEUTICS

Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

(2010) Ron J. Keizer et al.   CLINICAL PHARMACOKINETICS

Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

(2008) W Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Rituximab levels in cerebrospinal fluid of patients with neurological autoimmune disorders

(2008) HF Petereit et al.   Multiple Sclerosis Journal