Cytoprotective autophagy as a pro-survival strategy in ART-resistant malaria parasites

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival

(2021) Sachel Mok et al.   Nature Communications

A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites

(2020) Jakob Birnbaum et al.   SCIENCE

The role of autophagy in resistance to targeted therapies

(2020) Luigi Mele et al.   CANCER TREATMENT REVIEWS

Endocytosis in Plasmodium and Toxoplasma Parasites

(2020) Tobias Spielmann et al.   TRENDS IN PARASITOLOGY

At a glance: A history of autophagy and cancer

(2019) Xin Wen et al.   SEMINARS IN CANCER BIOLOGY

Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance

(2019) Tuo Yang et al.   Cell Reports

Remodeling of the malaria parasite and host human red cell by vesicle amplification that induces artemisinin resistance

(2018) Souvik Bhattacharjee et al.   BLOOD

Mechanisms of artemisinin resistance in Plasmodium falciparum malaria

(2018) Niraja Suresh et al.   CURRENT OPINION IN PHARMACOLOGY

Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia

(2017) Ankit Dwivedi et al.   MALARIA JOURNAL

Nutrient sensing modulates malaria parasite virulence

(2017) Liliana Mancio-Silva et al.   NATURE

Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells

(2017) Perle Latré de Laté et al.   Biomedical Journal

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

(2015) Alassane Mbengue et al.   NATURE

How cells coordinate waste removal through their major proteolytic pathways

(2015) Sascha Martens et al.   NATURE CELL BIOLOGY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

PLIP: fully automated protein–ligand interaction profiler

(2015) Sebastian Salentin et al.   NUCLEIC ACIDS RESEARCH

The demographics of the ubiquitin system

(2015) Michael J. Clague et al.   TRENDS IN CELL BIOLOGY

Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

(2015) Con Dogovski et al.   PLOS BIOLOGY

Metamorphoses of malaria: the role of autophagy in parasite differentiation

(2015) Isabelle Coppens   Essays in Biochemistry

Role of Autophagy in Cisplatin Resistance in Ovarian Cancer Cells

(2014) Juan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

(2014) Baptiste Ronan et al.   Nature Chemical Biology

Characterization of the Autophagy Marker Protein Atg8 Reveals Atypical Features of Autophagy in Plasmodium falciparum

(2014) Rahul Navale et al.   PLoS One

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

(2014) S. Mok et al.   SCIENCE

The multifunctional autophagy pathway in the human malaria parasite, Plasmodium falciparum

(2013) Serena Cervantes et al.   Autophagy

Plasmodium falciparumATG8 implicated in both autophagy and apicoplast formation

(2013) Andrew M Tomlins et al.   Autophagy

A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

(2013) David Gaviria et al.   PLoS One

Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state

(2012) S. E. Babbitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum, is exported to the host erythrocyte and is involved in hemoglobin trafficking

(2010) A. Vaid et al.   BLOOD

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Metamorphosis of the malaria parasite in the liver is associated with organelle clearance

(2010) Bamini Jayabalasingham et al.   CELL RESEARCH