Trial of a Novel Oral Cannabinoid Formulation in Patients with Hypertension: A Double-Blind, Placebo-Controlled Pharmacogenetic Study

CBD supplementation reduces arterial blood pressure via modulation of the sympatho-chromaffin system: A substudy from the HYPER-H21-4 trial

(2023) Marko Kumric et al.   BIOMEDICINE & PHARMACOTHERAPY

Preclinical assessment of the abuse potential of purified botanical cannabidiol: self-administration, drug discrimination, and physical dependence

(2022) Royston A Gray et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cannabidiol and Cannabidiol Metabolites: Pharmacokinetics, Interaction with Food, and Influence on Liver Function

(2022) Kieran Shay Struebin Abbotts et al.   Nutrients

Chronic Effects of Effective Oral Cannabidiol Delivery on 24-h Ambulatory Blood Pressure and Vascular Outcomes in Treated and Untreated Hypertension (HYPER-H21-4): Study Protocol for a Randomized, Placebo-Controlled, and Crossover Study

(2022) Marko Kumric et al.   Journal of Personalized Medicine

Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol

(2021) Jessica L Beers et al.   DRUG METABOLISM AND DISPOSITION

­­­­­­Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions

(2021) Shamema Nasrin et al.   DRUG METABOLISM AND DISPOSITION

Allele frequencies of single nucleotide polymorphisms of clinically important drug-metabolizing enzymes CYP2C9, CYP2C19, and CYP3A4 in a Thai population

(2021) Rattanaporn Sukprasong et al.   Scientific Reports

Pharmacokinetics, Safety, and Tolerability of a Medicinal Cannabis Formulation in Patients with Chronic Non-cancer Pain on Long-Term High Dose Opioid Analgesia: A Pilot Study

(2021) Yvonne Bonomo et al.   Pain and Therapy

The effects of acute and sustained cannabidiol dosing for seven days on the haemodynamics in healthy men: A randomised controlled trial

(2020) Salahaden R. Sultan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

CYP2C19 Allele Frequencies in Over 2.2 Million Direct‐to‐Consumer Genetics Research Participants and the Potential Implication for Prescriptions in a Large Health System

(2020) Yelena Ionova et al.   CTS-Clinical and Translational Science

Cannabidiol and Abnormal Liver Chemistries in Healthy Adults: Results of a Phase 1 Clinical Trial

(2020) Paul B. Watkins et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Towards Better Delivery of Cannabidiol (CBD)

(2020) Sophie Anne Millar et al.   Pharmaceuticals

Recommendations for Clinical CYP2C9 Genotyping Allele Selection: A Joint Recommendation of the Association for Molecular Pathology and College of American Pathologists

(2019) Victoria M. Pratt et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

TEMPORARY REMOVAL: Blood Pressure and the New ACC/AHA Hypertension Guidelines

(2019) John M. Flack et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Examination of a New Delivery Approach for Oral Cannabidiol in Healthy Subjects: A Randomized, Double-Blinded, Placebo-Controlled Pharmacokinetics Study

(2019) Alexander Patrician et al.   ADVANCES IN THERAPY

Defining screening panel of functional variants of CYP1A1, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 genes in Serbian population

(2019) Ivan Skadrić et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial

(2018) Philip McGuire et al.   AMERICAN JOURNAL OF PSYCHIATRY

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects

(2018) Lesley Taylor et al.   CNS DRUGS

A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans

(2018) Sophie A. Millar et al.   Frontiers in Pharmacology

Quality of Life in Childhood Epilepsy in pediatric patients enrolled in a prospective, open-label clinical study with cannabidiol

(2017) Evan C. Rosenberg et al.   EPILEPSIA

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

(2017) Orrin Devinsky et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Systematic Review and Meta-Analysis of the Haemodynamic Effects of Cannabidiol

(2017) Salahaden R. Sultan et al.   Frontiers in Pharmacology

Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial

(2016) Orrin Devinsky et al.   LANCET NEUROLOGY

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

Cannabidiol as potential anticancer drug

(2012) Paola Massi et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

(2012) F M Leweke et al.   Translational Psychiatry

Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes

(2011) Rongrong Jiang et al.   LIFE SCIENCES

Effect of Thyroid Hormone on the Activity of CYP3A Enzyme in Humans

(2009) Norio Takahashi et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

(2007) R G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY