Clinical assessment of hepatic de novo lipogenesis in non-alcoholic fatty liver disease

Treatment of patients with type 2 diabetes and non-alcoholic fatty liver disease: current approaches and future directions

(2016) Kenneth Cusi   DIABETOLOGIA

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

(2016) Samir Softic et al.   DIGESTIVE DISEASES AND SCIENCES

Impaired Insulin Suppression of VLDL-Triglyceride Kinetics in Nonalcoholic Fatty Liver Disease

(2016) Marianne K. Poulsen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis

(2016) Matthew J. Armstrong et al.   JOURNAL OF HEPATOLOGY

Chokeberry attenuates the expression of genes related to de novo lipogenesis in the hepatocytes of mice with nonalcoholic fatty liver disease

(2016) Hyunjin Park et al.   NUTRITION RESEARCH

Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice

(2015) Ji-Young Ann et al.   Genes and Nutrition

Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: Findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop

(2015) Arun J. Sanyal et al.   HEPATOLOGY

Sex-Specific Differences in Hepatic Fat Oxidation and Synthesis May Explain the Higher Propensity for NAFLD in Men

(2015) Camilla Pramfalk et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Double-blind Randomized Placebo-controlled Clinical Trial of Omega 3 Fatty Acids for the Treatment of Diabetic Patients With Nonalcoholic Steatohepatitis

(2015) Srinivasan Dasarathy et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Recent advances in lipidomics for disease research

(2015) Li Yang et al.   JOURNAL OF SEPARATION SCIENCE

Associations of Erythrocyte Fatty Acids in the De Novo Lipogenesis Pathway with Proxies of Liver Fat Accumulation in the EPIC-Potsdam Study

(2015) Simone Jacobs et al.   PLoS One

Liver fat deposition and mitochondrial dysfunction in morbid obesity: An approach combining metabolomics with liver imaging and histology

(2015) Nahum Calvo   WORLD JOURNAL OF GASTROENTEROLOGY

Molecular mechanisms of fatty liver in obesity

(2015) Lixia Gan et al.   Frontiers of Medicine

De novo lipogenesis in metabolic homeostasis: More friend than foe?

(2015) Giovanni Solinas et al.   Molecular Metabolism

Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice

(2015) Ji-Young Ann et al.   Genes and Nutrition

Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis

(2014) Joseph J Lee et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Influence of virgin coconut oil-enriched diet on the transcriptional regulation of fatty acid synthesis and oxidation in rats – a comparative study

(2014) Sakunthala Arunima et al.   BRITISH JOURNAL OF NUTRITION

Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes

(2014) David A. Griffith et al.   JOURNAL OF MEDICINAL CHEMISTRY

De novo lipogenesis in health and disease

(2014) Fatima Ameer et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The Role of Dietary Sugars and De novo Lipogenesis in Non-Alcoholic Fatty Liver Disease

(2014) J. Moore et al.   Nutrients

Ambulatory Treatment of Type 2 Diabetes in the U.S., 1997–2012

(2013) Lydia W. Turner et al.   DIABETES CARE

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

(2013) Jennifer E. Lambert et al.   GASTROENTEROLOGY

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

(2013) Yuki Kawano et al.   JOURNAL OF GASTROENTEROLOGY

The global NAFLD epidemic

(2013) Rohit Loomba et al.   Nature Reviews Gastroenterology & Hepatology

Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

(2012) C. Flannery et al.   DIABETES

Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications

(2012) Kenneth Cusi   GASTROENTEROLOGY

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

Increased serum levels of lipogenic enzymes in patients with severe liver steatosis

(2012) Maria Notarnicola et al.   Lipids in Health and Disease

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humansin vivo

(2011) Faidon Magkos et al.   Clinical Lipidology

Risk of Bladder Cancer Among Diabetic Patients Treated With Pioglitazone: Interim report of a longitudinal cohort study

(2011) J. D. Lewis et al.   DIABETES CARE

Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: a randomised controlled study

(2011) C. Beysen et al.   DIABETOLOGIA

A Dual Sugar Challenge Test for Lipogenic Sensitivity to Dietary Fructose

(2011) Lisa C. Hudgins et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals

(2011) R. Rabol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relationships between hepatic stearoyl-CoA desaturase-1 activity and mRNA expression with liver fat content in humans

(2010) Andreas Peter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years

(2010) V. W.-S. Wong et al.   GUT

A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease

(2010) Giovanni Musso et al.   HEPATOLOGY

Metabolomic Assessment of the Effect of Dietary Cholesterol in the Progressive Development of Fatty Liver Disease

(2010) Maria Vinaixa et al.   JOURNAL OF PROTEOME RESEARCH

Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice

(2010) Todd C. Rideout et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Soft drinks consumption and nonalcoholic fatty liver disease

(2010) William Nseir   WORLD JOURNAL OF GASTROENTEROLOGY

Fatty Acid Synthase: Association with Insulin Resistance, Type 2 Diabetes, and Cancer

(2009) J. A. Menendez et al.   CLINICAL CHEMISTRY

Synthesis of specific fatty acids contributes to VLDL-triacylglycerol composition in humans with and without type 2 diabetes

(2009) M. S. Wilke et al.   DIABETOLOGIA

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

(2009) Kimber L. Stanhope et al.   JOURNAL OF CLINICAL INVESTIGATION

Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease

(2008) Hironori Mitsuyoshi et al.   HEPATOLOGY RESEARCH

A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes

(2008) Carine Beysen et al.   JOURNAL OF LIPID RESEARCH