Fatty Acid Binding Protein-1 (FABP1) and the Human FABP1 T94A Variant: Roles in the Endocannabinoid System and Dyslipidemias

GPR119: a promising target for nonalcoholic fatty liver disease

(2016) Jin Won Yang et al.   FASEB JOURNAL

From whole body to cellular models of hepatic triglyceride metabolism: man has got to know his limitations

(2015) Charlotte J. Green et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Loss of L-FABP, SCP-2/SCP-x, or both induces hepatic lipid accumulation in female mice

(2015) Gregory G. Martin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Relative contributions of L-FABP, SCP-2/SCP-x, or both to hepatic biliary phenotype of female mice

(2015) Gregory G. Martin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Human FABP1 T94A variant enhances cholesterol uptake

(2015) Huan Huang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Fatty Acid-binding Proteins (FABPs) Are Intracellular Carriers for Δ9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD)

(2015) Matthew W. Elmes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of oleoylethanolamide on diet-induced nonalcoholic fatty liver in rats

(2015) Long Li et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Association of L-FABP T94A and MTP I128T Polymorphisms with Hyperlipidemia in Chinese Subjects

(2015) Yingying Tian et al.   LIPIDS

Fatty Acid Binding Protein Deletion Suppresses Inflammatory Pain through Endocannabinoid/N-Acylethanolamine-Dependent Mechanisms

(2015) Martin Kaczocha et al.   Molecular Pain

Enterocyte fatty acid-binding proteins (FABPs): Different functions of liver and intestinal FABPs in the intestine

(2015) Angela M. Gajda et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Fish Oil Decreases Hepatic Lipogenic Genes in Rats Fasted and Refed on a High Fructose Diet

(2015) Gabriela de Castro et al.   Nutrients

Ablating L-FABP in SCP-2/SCP-x null mice impairs bile acid metabolism and biliary HDL-cholesterol secretion

(2014) Gregory G. Martin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Human FABP1 T94A variant impacts fatty acid metabolism and PPAR-α activation in cultured human female hepatocytes

(2014) Avery L. McIntosh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Structural and functional interaction of fatty acids with human liver fatty acid-binding protein (L-FABP) T94A variant

(2014) Huan Huang et al.   FEBS Journal

Fatty Acid-binding Protein 5 (FABP5) Regulates Cognitive Function Both by Decreasing Anandamide Levels and by Activating the Nuclear Receptor Peroxisome Proliferator-activated Receptor β/δ (PPARβ/δ) in the Brain

(2014) Shuiliang Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyunsaturated fatty acids and their metabolites in brain function and disease

(2014) Richard P. Bazinet et al.   NATURE REVIEWS NEUROSCIENCE

Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia

(2014) Martin Kaczocha et al.   PLoS One

Omega-3 Fatty Acids, Hepatic Lipid Metabolism, and Nonalcoholic Fatty Liver Disease

(2013) E. Scorletti et al.   Annual Review of Nutrition

The Human Liver Fatty Acid Binding Protein T94A Variant Alters the Structure, Stability, and Interaction with Fibrates

(2013) Gregory G. Martin et al.   BIOCHEMISTRY

Ligand Binding Promiscuity of Human Liver Fatty Acid Binding Protein: Structural and Dynamic Insights from an Interaction Study with Glycocholate and Oleate

(2013) Filippo Favretto et al.   CHEMBIOCHEM

Interaction of Phthalates and Phenoxy Acid Herbicide Environmental Pollutants with Intestinal Intracellular Lipid Binding Proteins

(2013) Vincenzo Carbone et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The effect of LXRα, ChREBP and Elovl6 in liver and white adipose tissue on medium- and long-chain fatty acid diet-induced insulin resistance

(2013) He Sun et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Transport of endocannabinoids across the plasma membrane and within the cell

(2013) Christopher J. Fowler   FEBS Journal

Liver-type fatty acid binding protein interacts with hepatocyte nuclear factor 4α

(2013) Avery L. McIntosh et al.   FEBS LETTERS

Dual Role of MicroRNAs in NAFLD

(2013) Sara Ceccarelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Liver Fatty Acid-binding Protein Binds Monoacylglycerolin Vitroand in Mouse Liver Cytosol

(2013) William S. Lagakos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolite Regulation of Nucleo-cytosolic Trafficking of Carbohydrate Response Element-binding Protein (ChREBP)

(2013) Tsutomu Nakagawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

(2013) Yuki Kawano et al.   JOURNAL OF GASTROENTEROLOGY

Role of liver fatty acid binding protein in hepatocellular injury: Effect of CrPic treatment

(2013) Weijiang Fan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Role of FAAH-Like Anandamide Transporter in Anandamide Inactivation

(2013) KwanNok Leung et al.   PLoS One

Fatty Acid Modulation of the Endocannabinoid System and the Effect on Food Intake and Metabolism

(2013) Shaan S. Naughton et al.   International Journal of Endocrinology

Inhibitors of Fatty Acid Synthesis Induce PPARα-Regulated Fatty Acidβ-Oxidative Genes: Synergistic Roles of L-FABP and Glucose

(2013) Huan Huang et al.   PPAR Research

Interactions between Human Liver Fatty Acid Binding Protein and Peroxisome Proliferator Activated Receptor Selective Drugs

(2013) Tony Velkov   PPAR Research

Hepatic Fatty Acid Trafficking: Multiple Forks in the Road

(2013) Douglas G. Mashek   Advances in Nutrition

The role of endocannabinoids system in fatty liver disease and therapeutic potentials

(2013) KhalidA Alswat   Saudi Journal of Gastroenterology

Regulation of GPR119 receptor activity with endocannabinoid-like lipids

(2012) Samreen K. Syed et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Loss of intracellular lipid binding proteins differentially impacts saturated fatty acid uptake and nuclear targeting in mouse hepatocytes

(2012) Stephen M. Storey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Impact of L-FABP and glucose on polyunsaturated fatty acid induction of PPARα-regulated β-oxidative enzymes

(2012) Anca D. Petrescu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Endoplasmic Reticulum Stress in Nonalcoholic Fatty Liver Disease

(2012) Michael J. Pagliassotti   Annual Review of Nutrition

Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein: Fatty Acid Binding Revisited

(2012) Jun Cai et al.   BIOPHYSICAL JOURNAL

PPARα/HNF4α Interplay on Diversified Responsive Elements. Relevance in the Regulation of Liver Peroxisomal Fatty Acid Catabolism

(2012) Julie Chamouton et al.   CURRENT DRUG METABOLISM

Non-alcoholic fatty liver disease and insulin resistance: From bench to bedside

(2012) K. Gariani et al.   DIABETES & METABOLISM

Cannabinoid 1 receptor in fatty liver

(2012) Simon Eringsmark Regnell   HEPATOLOGY RESEARCH

Dynamic changes to the endocannabinoid system in models of chronic pain

(2012) D. Rani Sagar et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Common Variants of the Liver Fatty Acid Binding Protein Gene Influence the Risk of Type 2 Diabetes and Insulin Resistance in Spanish Population

(2012) Maria Luisa Mansego et al.   PLoS One

Different functions of intestinal and liver-type fatty acid-binding proteins in intestine and in whole body energy homeostasis

(2011) William Stacy Lagakos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genetic modifiers of non-alcoholic fatty liver disease progression

(2011) Quentin M. Anstee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Polymorphisms in fatty acid binding protein 5 show association with type 2 diabetes

(2011) Liming Bu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Use of Fibrates in the United States and Canada

(2011) Cynthia A. Jackevicius   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Fatty Acid-binding Proteins TransportN-Acylethanolamines to Nuclear Receptors and Are Targets of Endocannabinoid Transport Inhibitors

(2011) Martin Kaczocha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of chemical and thermal protein denaturation by combination of computational and experimental approaches. II

(2011) Qian Wang et al.   JOURNAL OF CHEMICAL PHYSICS

Acyl-CoA binding proteins interact with the acyl-CoA binding domain of mitochondrial carnitine palmitoyl transferase I

(2011) Heather A. Hostetler et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Fatty acid transport into the brain: Of fatty acid fables and lipid tails

(2011) Ryan W. Mitchell et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Role of Cannabinoids in the Development of Fatty Liver (Steatosis)

(2010) Vishnudutt Purohit et al.   AAPS Journal

The Endocannabinoid System and Its Relevance for Nutrition

(2010) Mauro Maccarrone et al.   Annual Review of Nutrition

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

(2010) Dina G. Tiniakos et al.   Annual Review of Pathology-Mechanisms of Disease

Millisecond Timescale Dynamics of Human Liver Fatty Acid Binding Protein: Testing of Its Relevance to the Ligand Entry Process

(2010) Dong Long et al.   BIOPHYSICAL JOURNAL

Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein

(2010) Jun Cai et al.   BIOPHYSICAL JOURNAL

A Review on the Monoacylglycerol Lipase: At the Interface Between Fat and Endocannabinoid Signalling

(2010) G. Labar et al.   CURRENT MEDICINAL CHEMISTRY

Genome-Wide Association Study Identifies Variants Associated With Histologic Features of Nonalcoholic Fatty Liver Disease

(2010) Naga Chalasani et al.   GASTROENTEROLOGY

Endocannabinoids in liver disease

(2010) Joseph Tam et al.   HEPATOLOGY

Fenofibrate Increases Very Low Density Lipoprotein Triglyceride Production Despite Reducing Plasma Triglyceride Levels in APOE*3-Leiden.CETP Mice

(2010) Silvia Bijland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IGFBP-3 Can Either Inhibit or Enhance EGF-mediated Growth of Breast Epithelial Cells Dependent upon the Presence of Fibronectin

(2010) Jamie McIntosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Validation and application of an LC–MS/MS method for quantitation of three fatty acid ethanolamides as biomarkers for fatty acid hydrolase inhibition in human plasma

(2010) Wenying Jian et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Glucose regulates fatty acid binding protein interaction with lipids and peroxisome proliferator-activated receptor α

(2010) Heather A. Hostetler et al.   JOURNAL OF LIPID RESEARCH

Liver fatty acid-binding protein and obesity

(2010) Barbara P. Atshaves et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Fibrates in CVD: a step towards personalised medicine

(2010) Bart Staels   LANCET

L-FABP T94A decreased fatty acid uptake and altered hepatic triglyceride and cholesterol accumulation in Chang liver cells stably transfected with L-FABP

(2010) Na Gao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA)

(2010) Natsuo Ueda et al.   PROGRESS IN LIPID RESEARCH

Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia

(2009) Neil M. Goldenberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Liver type fatty acid binding protein (L-FABP) gene ablation reduces nuclear ligand distribution and peroxisome proliferator-activated receptor-α activity in cultured primary hepatocytes

(2009) Avery L. McIntosh et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Human Liver Fatty Acid Binding Protein: Solution Structure and Ligand Binding

(2009) Jun Cai et al.   BIOPHYSICAL JOURNAL

Buffer Interference with Protein Dynamics: A Case Study on Human Liver Fatty Acid Binding Protein

(2009) Dong Long et al.   BIOPHYSICAL JOURNAL

Differential expression of lumican and fatty acid binding protein-1: New insights into the histologic spectrum of nonalcoholic fatty liver disease

(2009) Michael Charlton et al.   HEPATOLOGY

Fibrates in the prevention of cardiovascular disease in patients with type 2 diabetes mellitus – A pooled meta-analysis of randomized placebo-controlled clinical trials

(2009) Sandeep A. Saha et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Lipid Droplets Are Novel Sites ofN-Acylethanolamine Inactivation by Fatty Acid Amide Hydrolase-2

(2009) Martin Kaczocha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fenofibrate Simultaneously Induces Hepatic Fatty Acid Oxidation, Synthesis, and Elongation in Mice

(2009) Maaike H. Oosterveer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

L-FABP directly interacts with PPARα in cultured primary hepatocytes

(2009) Heather A. Hostetler et al.   JOURNAL OF LIPID RESEARCH

Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity

(2009) Jing Yan et al.   JOURNAL OF LIPID RESEARCH

Probing the Fibrate Binding Specificity of Rat Liver Fatty Acid Binding Protein

(2009) Sara Chuang et al.   JOURNAL OF MEDICINAL CHEMISTRY

High Dietary Fat Exacerbates Weight Gain and Obesity in Female Liver Fatty Acid Binding Protein Gene-Ablated Mice

(2009) Barbara P. Atshaves et al.   LIPIDS

Intestinal Lymphatic Transport Enhances the Post-Prandial Oral Bioavailability of a Novel Cannabinoid Receptor Agonist Via Avoidance of First-Pass Metabolism

(2009) Natalie L. Trevaskis et al.   PHARMACEUTICAL RESEARCH

Transcriptional profiling reveals divergent roles of PPARα and PPARβ/δ in regulation of gene expression in mouse liver

(2009) Linda M. Sanderson et al.   PHYSIOLOGICAL GENOMICS

Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human

(2009) Maryam Rakhshandehroo et al.   PLoS One

Identification of intracellular carriers for the endocannabinoid anandamide

(2009) M. Kaczocha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligand-enhanced expression and in-cell assay of human peroxisome proliferator-activated receptor alpha ligand binding domain

(2009) Tony Velkov et al.   PROTEIN EXPRESSION AND PURIFICATION

Endocannabinoids Can Open the Pain Gate

(2009) M. J. Christie et al.   Science Signaling

Gene expression in human NAFLD

(2008) Dario Greco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Emerging Functions and Mechanisms of Mammalian Fatty Acid–Binding Proteins

(2008) Judith Storch et al.   Annual Review of Nutrition

‘Entourage’ effects ofN-palmitoylethanolamide andN-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors

(2008) W-SV Ho et al.   BRITISH JOURNAL OF PHARMACOLOGY

Docosahexaenoic acid (DHA) and hepatic gene transcription

(2008) Donald B. Jump et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

(2008) Douglas Osei-Hyiaman et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of the Drug Binding Specificity of Rat Liver Fatty Acid Binding Protein

(2008) Sara Chuang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Liver fatty acid binding protein gene ablation enhances age-dependent weight gain in male mice

(2008) Gregory G. Martin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS

Fatty Acid Binding Protein: Localization and Functional Significance in the Brain

(2008) Yuji Owada   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Fibrates and future PPARα agonists in the treatment of cardiovascular disease

(2008) Bart Staels et al.   Nature clinical practice. Cardiovascular medicine

A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet

(2007) January N. Baumgardner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY