Microgravity alters the expressions of DNA repair genes and their regulatory miRNAs in space-flown Caenorhabditis elegans

Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans

(2021) Ricardo Laranjeiro et al.   iScience

Fidelity of a Bacterial DNA Polymerase in Microgravity, a Model for Human Health in Space

(2021) Aaron H Rosenstein et al.   Frontiers in Cell and Developmental Biology

The Determinant of DNA Repair Pathway Choices in Ionising Radiation-Induced DNA Double-Strand Breaks

(2020) Lei Zhao et al.   Biomed Research International

Differential modification of the C. elegans proteome in response to acute and chronic gamma radiation: Link with reproduction decline

(2019) Cécile Dubois et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Identification of potential radiation-responsive biomarkers based on human orthologous genes with possible roles in DNA repair pathways by comparison between Arabidopsis thaliana and homo sapiens

(2019) Lei Zhao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effect of simulated microgravity and ionizing radiation on expression profiles of miRNA, lncRNA, and mRNA in human lymphoblastoid cells

(2019) Hanjiang Fu et al.   Life Sciences in Space Research

Effect of dys-1 mutation on gene expression profile in space-flown Caenorhabditis elegans

(2018) Dan Xu et al.   MUSCLE & NERVE

Recent Progress in Space Physiology and Aging

(2018) Felice Strollo et al.   Frontiers in Physiology

IL-6 and the dysregulation of immune, bone, muscle, and metabolic homeostasis during spaceflight

(2018) John Kelly Smith   NPJ Microgravity

The DNA damage response of C. elegans affected by gravity sensing and radiosensitivity during the Shenzhou-8 spaceflight

(2017) Ying Gao et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Interplay of space radiation and microgravity in DNA damage and DNA damage response

(2017) María Moreno-Villanueva et al.   NPJ Microgravity

Transient gene and microRNA expression profile changes of confluent human fibroblast cells in spaceflight

(2016) Ye Zhang et al.   FASEB JOURNAL

Mining potential biomarkers associated with space flight in Caenorhabditis elegans experienced Shenzhou-8 mission with multiple feature selection techniques

(2016) Lei Zhao et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans

(2016) Akira Higashibata et al.   NPJ Microgravity

Effects of microgravity on DNA damage response in Caenorhabditis elegans during Shenzhou-8 spaceflight

(2015) Ying Gao et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Changes in apoptotic microRNA and mRNA expression profiling inCaenorhabditis elegansduring the Shenzhou-8 mission

(2015) Ying Gao et al.   JOURNAL OF RADIATION RESEARCH

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Dystrophin Involved in the Susceptibility of Slow Muscles to Hindlimb Unloading via Concomitant Activation of TGF-β1/Smad3 Signaling and Ubiquitin–Proteasome Degradation in Mice

(2014) Peng Zhang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

German SIMBOX on Chinese mission Shenzhou-8: Europe's first bilateral cooperation utilizing China's Shenzhou programme

(2013) Peter Preu et al.   ACTA ASTRONAUTICA

Autophagy activity contributes to programmed cell death inCaenorhabditis elegans

(2013) Haibin Wang et al.   Autophagy

Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts

(2013) Bingrong Dang et al.   LIFE SCIENCES

Synergistic Effects of Incubation in Rotating Bioreactors and Cumulative Low Dose 60Co γ-ray Irradiation on Human Immortal Lymphoblastoid Cells

(2012) Lijun Wei et al.   MICROGRAVITY SCIENCE AND TECHNOLOGY

Analysis of miRNA and mRNA Expression Profiles Highlights Alterations in Ionizing Radiation Response of Human Lymphocytes under Modeled Microgravity

(2012) Cristina Girardi et al.   PLoS One

Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

(2012) Yoko Honda et al.   Scientific Reports

Neural integrity is maintained by dystrophin inC. elegans

(2011) Shan Zhou et al.   JOURNAL OF CELL BIOLOGY

The Effectiveness of RNAi in Caenorhabditis elegans Is Maintained during Spaceflight

(2011) Timothy Etheridge et al.   PLoS One

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Review of the results from the International C. elegans first experiment (ICE-FIRST)

(2009) A.A. Adenle et al.   ADVANCES IN SPACE RESEARCH

Detection of space radiation-induced double strand breaks as a track in cell nucleus

(2009) Takeo Ohnishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

QuickGO: a web-based tool for Gene Ontology searching

(2009) D. Binns et al.   BIOINFORMATICS

Acclimation during space flight: effects on human physiology

(2009) D. Williams et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

(2009) Brandi N Davis et al.   Cell Communication and Signaling

Simulated microgravity decreases DNA repair capacity and induces DNA damage in human lymphocytes

(2009) Ragini Kumari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

DNA repair in modeled microgravity: Double strand break rejoining activity in human lymphocytes irradiated with γ-rays

(2009) Maddalena Mognato et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE