Recurrent genetic defects in classical Hodgkin lymphoma cell lines

Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells

(2014) J. Reichel et al.   BLOOD

The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing

(2014) Y Liu et al.   LEUKEMIA

Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma

(2014) Jay Gunawardana et al.   NATURE GENETICS

Development of Hodgkin lymphoma in homozygotic triplets with constitutional deletion in MKL1

(2013) M. Bjorkholm et al.   BLOOD

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Centriole biogenesis in multiciliated cells

(2013) Tang K. Tang   NATURE CELL BIOLOGY

Hodgkin-Reed-Sternberg Cells in Classical Hodgkin Lymphoma Show Alterations of Genes Encoding the NADPH Oxidase Complex and Impaired Reactive Oxygen Species Synthesis Capacity

(2013) Maciej Giefing et al.   PLoS One

Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma

(2012) E. Tiacci et al.   BLOOD

Deletion of the TNFAIP3/A20gene detected by FICTION analysis in classical Hodgkin lymphoma

(2012) Junko Nomoto et al.   BMC CANCER

Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphoma

(2012) Claudia Otto et al.   BRITISH JOURNAL OF HAEMATOLOGY

The role of ALFY in selective autophagy

(2012) P Isakson et al.   CELL DEATH AND DIFFERENTIATION

Constitutive AP-1 Activity and EBV Infection Induce PD-L1 in Hodgkin Lymphomas and Posttransplant Lymphoproliferative Disorders: Implications for Targeted Therapy

(2012) M. R. Green et al.   CLINICAL CANCER RESEARCH

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

ETS1 encoding a transcription factor involved in B-cell differentiation is recurrently deleted and down-regulated in classical Hodgkin's lymphoma

(2012) B. M. Overbeck et al.   HAEMATOLOGICA

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

NPAT mutations in Hodgkin lymphoma

(2011) R. Kuppers   BLOOD

Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma

(2011) S. Saarinen et al.   BLOOD

JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma

(2011) K. Van Roosbroeck et al.   BLOOD

Mutations in a gene encoding a midbody protein in binucleated Reed-Sternberg cells of Hodgkin lymphoma

(2011) Maxwell M. Krem et al.   CELL CYCLE

MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

(2011) Christian Steidl et al.   NATURE

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

(2010) M. R. Green et al.   BLOOD

Cooperative Epigenetic Modulation by Cancer Amplicon Genes

(2010) Lixin Rui et al.   CANCER CELL

Mutations of NFKBIA in biopsy specimens from Hodgkin lymphoma

(2010) Xiaojian Liu et al.   CANCER GENETICS AND CYTOGENETICS

Nebulin, a major player in muscle health and disease

(2010) Siegfried Labeit et al.   FASEB JOURNAL

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)

(2010) Victor Enciso-Mora et al.   NATURE GENETICS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Pathogenesis of Classical and Lymphocyte-Predominant Hodgkin Lymphoma

(2009) Roland Schmitz et al.   Annual Review of Pathology-Mechanisms of Disease

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities

(2009) A. Mottok et al.   BLOOD

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Mutations ofNFKBIA, encoding IκBα, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases

(2009) Annette Lake et al.   INTERNATIONAL JOURNAL OF CANCER

TNFAIP3(A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

(2009) Roland Schmitz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of candidate tumour suppressor gene loci for Hodgkin and Reed-Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines

(2008) Maciej Giefing et al.   BRITISH JOURNAL OF HAEMATOLOGY

BCL2 and BCL3 are recurrent translocation partners of the IGH locus

(2008) Natalia Szymanowska et al.   CANCER GENETICS AND CYTOGENETICS

Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization

(2008) S. Hartmann et al.   HAEMATOLOGICA