CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor

Landscape of cancer-associated fibroblasts identifies the secreted biglycan as a protumor and immunosuppressive factor in triple-negative breast cancer

(2022) Shaoquan Zheng et al.   OncoImmunology

USP12 positively regulates M‐MDSC function to inhibit antitumour immunity through deubiquitinating and stabilizing p65

(2022) Xiaoxia Zhan et al.   IMMUNOLOGY

Implication of cancer associated fibroblast subtypes on cancer pathogenesis, prognosis, and immunotherapy resistance

(2021) Phillip M Galbo et al.   CLINICAL CANCER RESEARCH

Cancer‐associated fibroblast‐mediated cellular crosstalk supports hepatocellular carcinoma progression

(2021) Mengjia Song et al.   HEPATOLOGY

Inference and analysis of cell-cell communication using CellChat

(2021) Suoqin Jin et al.   Nature Communications

The IKZF1–IRF4/IRF5 Axis Controls Polarization of Myeloma-Associated Macrophages

(2021) Dimitrios Mougiakakos et al.   Cancer Immunology Research

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

(2021) Silvia Affo et al.   CANCER CELL

CAFs shape myeloid‐derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma via 5‐lipoxygenase

(2021) Yuli Lin et al.   HEPATOLOGY

Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma

(2021) Lichun Ma et al.   JOURNAL OF HEPATOLOGY

Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms

(2021) Haichuan Hu et al.   CANCER CELL

TGF-β orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer

(2021) Luciana Gneo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma: An Update on Heterogeneity and Therapeutic Targeting

(2021) Utpreksha Vaish et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcription factor RUNX3 promotes CD8 + T cell recruitment by CCL3 and CCL20 in lung adenocarcinoma immune microenvironment

(2020) Qian Song et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

scTyper: a comprehensive pipeline for the cell typing analysis of single-cell RNA-seq data

(2020) Ji-Hye Choi et al.   BMC BIOINFORMATICS

Myeloid-derived suppressor cells are essential partners for immune checkpoint inhibitors in the treatment of cisplatin-resistant bladder cancer

(2020) Yuji Takeyama et al.   CANCER LETTERS

Single-cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinoma

(2020) Min Zhang et al.   JOURNAL OF HEPATOLOGY

Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma

(2020) Ankur Sharma et al.   CELL

Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance

(2020) Jiaye Liu et al.   Cellular and Molecular Gastroenterology and Hepatology

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline

(2020) John D. Gordan et al.   JOURNAL OF CLINICAL ONCOLOGY

The Trends of Single-Cell Analysis: A Global Study

(2020) Hua Tian et al.   Biomed Research International

Determining cell type abundance and expression from bulk tissues with digital cytometry

(2019) Aaron M. Newman et al.   NATURE BIOTECHNOLOGY

β-Catenin Activation Promotes Immune Escape and Resistance to Anti–PD-1 Therapy in Hepatocellular Carcinoma

(2019) Marina Ruiz de Galarreta et al.   Cancer Discovery

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

(2019) Ela Elyada et al.   Cancer Discovery

Heterogeneity of cancer-associated fibroblasts and roles in the progression, prognosis, and therapy of hepatocellular carcinoma

(2019) Zeli Yin et al.   Journal of Hematology & Oncology

C/EBPδ-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake

(2019) Dongmei Wang et al.   ONCOGENE

Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma

(2019) Qiang Gao et al.   CELL

Reliability of a single-region sample to evaluate tumor immune microenvironment in hepatocellular carcinoma

(2019) Ying-Chun Shen et al.   JOURNAL OF HEPATOLOGY

Inducing and exploiting vulnerabilities for the treatment of liver cancer

(2019) Cun Wang et al.   NATURE

The Human Transcription Factors

(2018) Samuel A. Lambert et al.   CELL

Nitric Oxide Production by Myeloid-Derived Suppressor Cells Plays a Role in Impairing Fc Receptor–Mediated Natural Killer Cell Function

(2018) Andrew Stiff et al.   CLINICAL CANCER RESEARCH

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Targeting the crosstalk between cytokine-induced killer cells and myeloid-derived suppressor cells in hepatocellular carcinoma

(2018) Su Jong Yu et al.   JOURNAL OF HEPATOLOGY

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation

(2017) Yury I. Miller et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling

(2016) Xuguang Yang et al.   CANCER RESEARCH

Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers

(2016) Ingrid Lua et al.   JOURNAL OF HEPATOLOGY

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

(2015) Shabnam Shalapour et al.   NATURE

Twist1 Is a Key Regulator of Cancer-Associated Fibroblasts

(2014) K.-W. Lee et al.   CANCER RESEARCH

Selection of an Antibody Library Identifies a Pathway to Induce Immunity by Targeting CD36 on Steady-State CD8 + Dendritic Cells

(2014) E. Tagliani et al.   JOURNAL OF IMMUNOLOGY

Glycogen synthase kinase-3β–mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promot es migration and activation of microglia/macrophages

(2013) Chiung-Yuan Ko et al.   NEUROBIOLOGY OF AGING

MIF: metastasis/MDSC-inducing factor?

(2013) Kendra D. Simpson et al.   OncoImmunology

MEF2C Ablation in Endothelial Cells Reduces Retinal Vessel Loss and Suppresses Pathologic Retinal Neovascularization in Oxygen-Induced Retinopathy

(2012) Zhenhua Xu et al.   AMERICAN JOURNAL OF PATHOLOGY

Macrophage Migration Inhibitory Factor Promotes Tumor Growth and Metastasis by Inducing Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2012) K. D. Simpson et al.   JOURNAL OF IMMUNOLOGY

Hepatic acute phase proteins – Regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling

(2011) Johannes G. Bode et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

C5a-regulated CCAAT/Enhancer-binding Proteins β and δ Are Essential in Fcγ Receptor-mediated Inflammatory Cytokine and Chemokine Production in Macrophages

(2011) Chunguang Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting

(2009) J. M. McClung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Lipid-induced Insulin Resistance Is Associated With Increased Monocyte Expression of Scavenger Receptor CD36 and Internalization of Oxidized LDL

(2009) Sangeeta R. Kashyap et al.   Obesity

Expression of hepatitis B virus proteins in transgenic mice alters lipid metabolism and induces oxidative stress in the liver

(2007) Fu Yang et al.   JOURNAL OF HEPATOLOGY