Article
Chemistry, Physical
Cyprien Muller, Aymeric Ontani, Alexis Bigo-Simon, Pierre Schaaf, Loic Jierry
Summary: Nature utilizes enzymatic actions to achieve high levels of control, resulting in local formation and kinetic tuning of supramolecular structures through self-assembly. This offers new perspectives for designing novel materials.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Article
Pharmacology & Pharmacy
Wei Zhou, Jiandong Huang, Qingwei Xiao, Shunmin Hu, Shijia Li, Jie Zheng, Zhiyun Du, Jiangling Peng, Huixiong Chen
Summary: Innovatively labeled superparamagnetic iron oxide nanoparticles with a PSMA-targeting Glu-Urea-Lys scaffold were successfully used as a probe for in vivo molecular imaging of prostate cancer. The probe showed high binding affinity and specificity, and demonstrated the potential to enhance magnetic resonance detection of prostate cancer.
Article
Chemistry, Physical
Eric J. M. Lang, Emily G. Baker, Derek N. Woolfson, Adrian J. Mulholland
Summary: We tested a range of standard GB models and protein force fields on a set of designed peptides and found that none of the models accurately predicted the a-helical content for all peptides. These peptides serve as a useful test set for simulation methods.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
(2022)
Article
Medicine, Research & Experimental
Ping Cai, Sufan Tang, Li Xia, Yinwen Wang, Yang Liu, Yue Feng, Nan Liu, Yue Chen, Zhijun Zhou
Summary: Since PSMA is upregulated in prostate cancer, it can be used as a diagnostic biomarker and treatment target. This study developed five PSMA-targeted tracers and compared their pharmacokinetics to a commonly used tracer. The tracers showed efficient uptake and internalization into cancer cells, and enabled clear visualization of tumors in PET images. The results suggest great potential for these tracers as new PET tracers in prostate cancer, with one tracer in particular showing higher tumor uptake.
MOLECULAR PHARMACEUTICS
(2023)
Article
Polymer Science
Rie Kakehashi, Naoji Tokai, Makoto Nakagawa, Kazunori Kawasaki, Shin Horiuchi, Atsushi Yamamoto
Summary: This study demonstrates the relationship between the length of methylene chains at four different locations of AAOs and the aggregate structure, gelation temperature, and viscoelasticity of the formed hydrogels. By changing the methylene chain lengths, the aggregate structure can be controlled as ribbon-like or rod-like. Furthermore, hydrogels consisting of rod-like aggregates exhibit significantly higher viscoelasticity compared to those consisting of ribbon-like aggregates. Therefore, the gel viscoelasticity can be controlled by adjusting the methylene chain lengths of AAOs at different positions.
Article
Food Science & Technology
Aleksandra Yu. Kroupina, Aleksey S. Yanovsky, Varvara A. Korobkova, Ludmila A. Bespalova, Andrey V. Arkhipov, Galina I. Bukreeva, Anastasiya D. Voropaeva, Pavel Yu. Kroupin, Dmitry Y. Litvinov, Aleksandra A. Mudrova, Daniil S. Ulyanov, Gennady I. Karlov, Mikhail G. Divashuk
Summary: This study analyzed the allelic state of high-molecular-weight glutenin genes Glu-A1 and Glu-B1 in 76 accessions of winter durum wheat and assessed grain and pasta quality traits in a two-year field experiment. The results showed that the Glu-A1a allele had a positive effect on the gluten index, while Glu-A1c had a negative effect. The Glu-B1al and Glu-B1f alleles had a positive effect on protein and gluten quality and quantity, and the Glu-A1c + Glu-B1al genotypes were closest to the high-quality category in protein-associated quality traits.
Article
Polymer Science
Jingyu Jin, Guoqiang Lu, Jun Nie, Xiaoqun Zhu
Summary: Photopolymerization technology is limited in the fields of food packaging and biomedicine due to the high migration of small molecules from photoinitiators. In this study, a polymerizable 2-vinyl thioxanthone (ETX) was synthesized to improve the migration stability of photoinitiators. Macromolecular photoinitiators (PPI1, PPI2) were also prepared to further reduce migration. The results showed that the ETX/TEOA system had higher initiation performance and PPI2 displayed favorable initiation ability. Additionally, the migration of ETX, PPI1, and PPI2 in photocured film was significantly reduced. These low-migration photoinitiators have potential applications in the fields of food packaging and biological materials.
EUROPEAN POLYMER JOURNAL
(2024)
Article
Polymer Science
Mohamed Mehawed Abdellatif, Noha M. Sabry, Saber Ibrahim, Samah M. Bassem, Wagdy K. B. Khalil, Fagr Kh. Abdel-Gawad
Summary: A large amount of oil leakage has significant impacts on aquatic environments, but organic gelators can help alleviate these effects and enhance the immunity of fish.
Article
Materials Science, Multidisciplinary
S. N. Danilova, A. N. Ivanov, A. M. Spiridonov, E. V. Abakunova, A. A. Okhlopkova
Summary: This paper studies the influence of organo-modified montmorillonite (oMMT) on the properties and structure of ultrahigh molecular weight polyethylene (UHMWPE). The technology of preliminary mechanical activation of oMMT in a planetary mill is proposed. It is found that preliminary mechanical activation leads to dispersion and increase in the porosity of oMMT. Heat treatment at the temperature of the composite material processing does not lead to the destruction of organic modifiers. The introduction of preliminary mechanically activated oMMT contributes to the increase of tensile and compressive strength of the composite material based on ultra-high molecular weight polyethylene.
MATERIALS TODAY COMMUNICATIONS
(2023)
Review
Biochemistry & Molecular Biology
Stefan Kubik
Summary: The study on the use of cyclic peptides or pseudopeptides as synthetic receptors began even before the field of supramolecular chemistry was established. Initially, the focus was on the development of synthetic ionophores using macrocycles with repeating subunit sequences to investigate the correlation between structure, conformation, and binding properties. With further research, cyclopeptides and related macrocycles have become an important and structurally diverse receptor family.
Article
Engineering, Environmental
Shanshan Wei, Bin Wang, Hongyuan Zhang, Chenzhao Wang, Shufeng Cui, Xiangyu Yin, Chunzhu Jiang, Guoying Sun
Summary: Amino acids are crucial in various physiological processes and the accurate monitoring of their metabolism remains a challenge. This study successfully synthesized multi-color emission carbon dots (CDs) that demonstrated bright and steady luminescence. These CDs exhibited low cytotoxicity and excellent multi-color cell imaging ability. Specifically, chiral red emissive CDs (R-L-CDs) were able to quickly identify specific amino acids in water and biological samples. The introduction of a smart phone color recognizer application improved the accuracy of visual detection. Overall, these findings have far-reaching prospects for the application of R-L-CDs as biosensors.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Mi Wu, Shun Mao, Xu Liu, Yunen Liu, Peifang Cong, Jianhua Lv, Huaqin Tian, Yan Zhao
Summary: This study developed self-gelling and bioadhesive powders made of chitosan and polyacrylic acid, which effectively manage irregularly shaped, complex, and non-compressible wounds. These powders demonstrated excellent mechanical properties, significant antibacterial activities, strong and lasting adhesion on wet tissues, and accelerated blood clotting. They have great potential in managing acute hemorrhage of non-compressible trauma.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Physical
Hyunjee Yoon, Seoyoon Shin, Sooyeol Park, Moo Whan Shin
Summary: Ionic liquids (ILs) have potential as electrolyte solvents for Li-air batteries due to their unique properties. However, the high viscosity of IL-based electrolytes limits battery performance. This study successfully synthesized low-viscosity ILs and demonstrated their improved performance in cell tests. The optimized IL N111(1O2) FSI showed significantly higher initial capacity compared to the reference material DEME FSI.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Applied
Zhiqing Tian, Fan Jiang, Haolong Cong, Shuifang Zhu
Summary: A gel permeation chromatography (GPC) method calibrated based on serrated peaks in chromatograms was developed to determine the molecular weight (MW) of low molecular weight (LWM) hyaluronic acid (HA) and chondroitin sulfate (CS). The method was validated using enzymolysis-based MW calibrants and showed high correlation coefficients in the standard curves. Measurement of a sample could be conducted in less than 30 minutes with minuscule discrepancies in MW values. The method was also capable of measuring very low MWs.
CARBOHYDRATE POLYMERS
(2023)
Review
Polymer Science
Xiaoyi Feng, Yuning Luo, Fangjie Li, Xueting Jian, Yang Liu
Summary: Natural small molecular drugs, with unique rigid backbone structures and modifiable multiple sites, have been utilized as building blocks to form low-molecular-weight supramolecular gels with high drug loading, low toxicity, and outstanding stimulus responsiveness. These gels have overcome the shortcomings of natural drugs and are widely used in biomedical fields, showing great potential for further research.
Article
Chemistry, Physical
Zhengjing Zhao, Donglai Li, Chengzhi Wang, Debao Fang, Boyu Wang, Jingbo Li, Haibo Jin
Summary: Hierarchical V2O5 microspheres (HVMs) synthesized in this study exhibit excellent electrochemical performance for sodium ion storage, especially at high discharge/charge rates. The material demonstrates high reversible capacities and limited decay over 500 cycles, attributed to fast Na+-ion diffusion and enhanced reaction kinetics through a pseudocapacitive process in the unique hollow structure.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Materials Science, Biomaterials
Zhiping Fang, Yonghao Xiao, Xue Geng, Liujun Jia, Yuehao Xing, Lin Ye, Yongquan Gu, Ai-ying Zhang, Zeng-guo Feng
Summary: Increasing problems in long-term hemodialysis have led to a demand for synthetic small diameter vascular prostheses. This study presents a bi-layered blood vessel made of thermoplastic poly(ether urethane) (TPU) and poly(epsilon-caprolactone) (PCL-Hep) for vascular access. The results show that this graft has excellent mechanical properties and biointegration regeneration capabilities, making it suitable for hemodialytic vascular access applications.
BIOMATERIALS ADVANCES
(2022)
Article
Biochemistry & Molecular Biology
Jingbo Li, Zhiqian Zhang, Qi Lei, Bugao Lu, Chenzhong Jin, Xiu Liu, Yanhui Wang, Lianyang Bai
Summary: Long-term reliance on herbicides for weed control in sugarcane fields of Guangxi Zhuang autonomous region has resulted in the evolution of resistance in Eleusine indica. This study examined 96 E. indica lines and found resistance to multiple herbicides, with various resistance mechanisms identified. Diversified weed control tactics should be implemented to prevent further resistance in E. indica.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2022)
Article
Agronomy
Mengge Huang, Di Long, Fengyan Zhou, Jingbo Li, Wenwei Tang, Dongqiang Zeng, Yanhui Wang
Summary: The transition from puddled-transplanted rice to direct-seeded rice is becoming more popular in central China, while the puddled-transplanted rice system remains the most common practice in southwest China. Weeds are a major problem in direct-seeded rice systems, and the increased use of herbicides has led to the rapid evolution of resistant weed populations.
Article
Oncology
Nannan Guo, Shaojun Li, Bo Liu, Ping Chen, Jingbo Li, Yunlong Zhao, Yingnan Zhao, Jian Tang, Wen Zhang
Summary: The combination of Ku70/80 heterodimer protein inhibitor STL127705 and gemcitabine was found to enhance the sensitivity of NSCLC cell lines to irradiation and induce apoptosis. This combination treatment effectively inhibits the NHEJ pathway and enhances DNA damage, leading to tumor cell death.
Article
Chemistry, Physical
Donglai Li, Zhengjing Zhao, Chengzhi Wang, Shanshan Deng, Junlin Yang, Xiaoqian Wang, Jingbo Li, Yongjie Zhao, Haibo Jin
Summary: Cation co-doping has been demonstrated as an effective approach to reduce the metal-insulator transition (MIT) temperature (theta(c)) of vanadium dioxide (VO2) for optical switching properties near room temperature. By co-doping Mg and W in VO2 films, it was observed that Mg dopants increase theta(c) at a rate of 22 degrees C per at% Mg with optimal effectiveness below 1 at% Mg content. XPS spectra show that Mg dopants counteract the VBE uplifting caused by W dopants, thereby enlarging the optical band gap and improving the visible light transmittance of W-doped VO2.
APPLIED SURFACE SCIENCE
(2022)
Article
Engineering, Environmental
Jingbo Li, Han Zhang, Lingyu Sun, Lu Fan, Xiao Fu, Xiaoyu Liu, Dechen Liu, Qiong Wei, Yuanjin Zhao, Stephen J. Pandol, Ling Li
Summary: This article introduces an advanced technique for pancreatic beta cell culture, which involves the generation of porous microcarriers with pancreatic beta cell aggregates using microfluidic double emulsion techniques. The research shows that these microcarriers can improve pancreatic function and promote insulin secretion. This study offers an attractive option for diabetes treatment.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Materials Science, Composites
Xiang Wang, Jiarui Dong, Chenyue Gong, Shaoyue Zhang, Jiale Yang, Aiying Zhang, Zengguo Feng
Summary: In this study, a new class of composite electrospun membranes was designed and fabricated by triggering the self-polymerization of dopamine onto the surface of PVDF electrospun fibers to form PDA coating, and subsequently binding beta-CD molecules on the fibers surface via hydrogen bonding. The resulting PVDF/PDA/beta-CD fibers exhibited core-shell structure with efficient adsorption performance towards methylene blue and phenolphthalein. The membranes were also bendable and displayed excellent mechanical performances.
COMPOSITES SCIENCE AND TECHNOLOGY
(2022)
Article
Optics
Lin Wang, Debao Fang, Haibo Jin, Jingbo Li
Summary: In this study, the reliability of standard RCWA for multilayer gratings with metal-dielectric structures was enhanced using the 2D modal solution of rigorous coupled wave analysis with adaptive spatial resolution. The conversion relation between the modal solutions in the Cartesian system and the transformed system was established for the first time. Numerical results showed that the proposed method achieved good convergence even for metal patches in the microwave band and was perfectly suitable for multi-layer structure calculation.
Article
Polymer Science
Rong-hao Song, Zhi-hua Liu, Xue Geng, Lin Ye, Ai-ying Zhang, Zeng-guo Feng
Summary: The use of slide-ring (SR) structure as an energy dissipation unit has the potential to toughen and damp a variety of polymer materials.
Article
Chemistry, Multidisciplinary
Qing Ni, Yongjie Zhao, Xuanyi Yuan, Jingbo Li, Haibo Jin
Summary: Recently, sodium-ion batteries have attracted great attention as a promising solution for energy storage. This study reports the use of Fe and Al doping to improve the cycling stability and rate capability of sodium-ion batteries. The experimental results show that the doped compounds can maintain a stable phase structure during cycling and enhance the electrode capacity through synergistic reactions.
Review
Biochemistry & Molecular Biology
Haojun Li, Meng Xu, Rui Shi, Aiying Zhang, Jiatao Zhang
Summary: This article reviews the application of electrospinning synthesis technology in functional fiber materials with metal and semiconductor nanocrystalline materials in recent years, and introduces several typical methods. The article also summarizes the specific application and prospects of electrospun nanofibers in the biomedical field, such as antimicrobial fibers and biosensing.
Article
Materials Science, Multidisciplinary
Zhiping Fang, Shaoyue Zhang, Han Wang, Xue Geng, Lin Ye, Ai-ying Zhang, Zeng-guo Feng
Summary: Coaxial solution and single-nozzle emulsion electrospinning techniques were used to fabricate core-shell structured nanofibers from mixed solutions of polymers. The resulting nanofibers had a core of biodegradable aliphatic polyesters surrounded by a shell of poly(ether urethane). The thickness of the core/shell layers could be adjusted by changing the feeding mass ratio of the polymers. The formation of core-shell nanofibers was attributed to the interaction between thermodynamic phase separation and stretching kinetic phase separation during electrospinning.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Materials Science, Biomaterials
Chengzhao Tu, Yuanguo Zhang, Yonghao Xiao, Yuehao Xing, Yuhao Jiao, Xue Geng, Aiying Zhang, Lin Ye, Yongquan Gu, Zengguo Feng
Summary: Tissue engineering is a promising strategy to develop successful small diameter vascular grafts (SDVG). This study focused on optimizing the fabrication of SDVGs by introducing natural substances into synthetic biomaterials, improving biocompatibility and promoting in vivo regeneration. Bioactive SDVGs were prepared by coating heparin-modified poly-(epsilon-caprolactone) scaffolds with vascular extracellular matrix (VECM) components. The SDVGs showed good endothelial cell proliferation and in vivo regeneration, indicating the specificity and effectiveness of the fabricated VECM-SDVGs.
BIOMATERIALS ADVANCES
(2022)
Article
Materials Science, Biomaterials
Zhiping Fang, Yuehao Xing, Han Wang, Xue Geng, Lin Ye, Ai-ying Zhang, Yongquan Gu, Zeng-guo Feng
Summary: In this study, a structurally reinforced bilayer vascular graft was fabricated by co-electrospinning thermoplastic polyurethane (TPU) and poly(epsilon-caprolactone) (PCL) onto the outer surface of PCL electrospun small-diameter single-layer vascular grafts (SLVGs), combined with surface heparinization. The resulting grafts demonstrated excellent mechanical strength, higher compliance, sustained release of heparin, and enhanced anti-coagulation activity. Furthermore, these grafts inhibited aneurysm formation and delayed calcification, while promoting neovascular tissue remodeling and elastin deposition. This study highlights the feasibility and efficacy of incorporating TPU into PCL-Hep small-diameter artificial vascular grafts.
BIOMATERIALS SCIENCE
(2022)