High-Throughput Screen Reveals the Structure–Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin

Comprehensive Mutational Analysis of the Lasso Peptide Klebsidin

(2022) Ethan Hills et al.   ACS Chemical Biology

Accurate Models of Substrate Preferences of Post-Translational Modification Enzymes from a Combination of mRNA Display and Deep Learning

(2022) Alexander A. Vinogradov et al.   ACS Central Science

Phenotype-Guided Comparative Genomics Identifies the Complete Transport Pathway of the Antimicrobial Lasso Peptide Ubonodin in Burkholderia

(2022) Truc Do et al.   ACS Chemical Biology

Triculamin: An Unusual Lasso Peptide with Potent Antimycobacterial Activity

(2022) Frederikke D. Andersen et al.   JOURNAL OF NATURAL PRODUCTS

Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter

(2022) Drew V. Carson et al.   ACS Infectious Diseases

Activity of imipenem-relebactam against multi-drug and extensively-drug resistant Burkholderia cepacia complex and Burkholderia gladioli

(2021) Scott A. Becka et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of the Class I Antimicrobial Lasso Peptide Arcumycin

(2021) Lydia M. Stariha et al.   CHEMBIOCHEM

Selection for constrained peptides that bind to a single target protein

(2021) Andrew M. King et al.   Nature Communications

PepVAE: Variational Autoencoder Framework for Antimicrobial Peptide Generation and Activity Prediction

(2021) Scott N. Dean et al.   Frontiers in Microbiology

Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin

(2019) Nathaniel R. Braffman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery and structure of the antimicrobial lasso peptide citrocin

(2019) Wai Ling Cheung-Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Lasso Peptide Siamycin-I Targets Lipid II at the Gram-Positive Cell Surface

(2019) Stephanie Tan et al.   ACS Chemical Biology

Analysis of modular bioengineered antimicrobial lanthipeptides at nanoliter scale

(2019) Steven Schmitt et al.   Nature Chemical Biology

“Switching Partners”: Piperacillin-Avibactam Is a Highly Potent Combination against Multidrug-Resistant Burkholderia cepacia Complex and Burkholderia gladioli Cystic Fibrosis Isolates

(2019) Elise T. Zeiser et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Discovery of ubonodin, an antimicrobial lasso peptide active against members of the Burkholderia cepacia complex

(2019) Wai Ling Cheung-Lee et al.   CHEMBIOCHEM

A lanthipeptide library used to identify a protein–protein interaction inhibitor

(2018) Xiao Yang et al.   Nature Chemical Biology

Development and Application of Yeast and Phage Display of Diverse Lanthipeptides

(2018) Kenton J. Hetrick et al.   ACS Central Science

Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein

(2017) Johannes H. Urban et al.   Nature Communications

Overcoming an Extremely Drug Resistant (XDR) Pathogen: Avibactam Restores Susceptibility to Ceftazidime for Burkholderia cepacia Complex Isolates from Cystic Fibrosis Patients

(2017) Krisztina M. Papp-Wallace et al.   ACS Infectious Diseases

Lasso Peptides: An Intriguing Class of Bacterial Natural Products

(2015) Julian D. Hegemann et al.   ACCOUNTS OF CHEMICAL RESEARCH

Efflux pump-mediated drug resistance in Burkholderia

(2015) Nicole L. Podnecky et al.   Frontiers in Microbiology

Cystic fibrosis

(2015) Felix Ratjen et al.   Nature Reviews Disease Primers

Differential Roles of RND Efflux Pumps in Antimicrobial Drug Resistance of Sessile and Planktonic Burkholderia cenocepacia Cells

(2014) Silvia Buroni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

(2014) Ekaterina Gavrish et al.   CHEMISTRY & BIOLOGY

Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides

(2014) Indran Mathavan et al.   Nature Chemical Biology

Lasso peptides: structure, function, biosynthesis, and engineering

(2012) Mikhail O. Maksimov et al.   NATURAL PRODUCT REPORTS

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

The Antibacterial Threaded-lasso Peptide Capistruin Inhibits Bacterial RNA Polymerase

(2011) Konstantin Kuznedelov et al.   JOURNAL OF MOLECULAR BIOLOGY

Sequence Diversity in the Lasso Peptide Framework: Discovery of Functional Microcin J25 Variants with Multiple Amino Acid Substitutions

(2011) Si Jia Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Systematic Structure-Activity Analysis of Microcin J25

(2008) Olga Pavlova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation and Structural Characterization of Capistruin, a Lasso Peptide Predicted from the Genome Sequence of Burkholderia thailandensis E264

(2008) Thomas A. Knappe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY