Exhaustion of CD8+ central memory responder T cell differentiation provokes non-melanoma skin cancer in elderly kidney transplant recipients

Chronic Kidney Failure Provokes the Enrichment of Terminally Differentiated CD8+ T Cells, Impairing Cytotoxic Mechanisms After Kidney Transplantation

(2022) Jonas Leonhard et al.   Frontiers in Immunology

Characteristics of circulating adaptive immune cells in patients with colorectal cancer

(2022) Longyi Zhang et al.   Scientific Reports

De NovoMalignancies after Kidney Transplantation

(2021) David Al-Adra et al.   Clinical Journal of the American Society of Nephrology

Impaired Differentiation of Highly Proliferative ICOS+-Tregs Is Involved in the Transition from Low to High Disease Activity in Systemic Lupus Erythematosus (SLE) Patients

(2021) Florian Kälble et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pre-transplant Thymic Function Predicts Is Associated With Patient Death After Kidney Transplantation

(2020) Cécile Courivaud et al.   Frontiers in Immunology

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

(2019) Brian C. Miller et al.   NATURE IMMUNOLOGY

CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer

(2019) Laura M. McLane et al.   Annual Review of Immunology

The Role of the Immune System in Cutaneous Squamous Cell Carcinoma

(2019) Matthew J. Bottomley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clonal replacement of tumor-specific T cells following PD-1 blockade

(2019) Kathryn E. Yost et al.   NATURE MEDICINE

The function and dysfunction of memory CD8+ T cells in tumor immunity

(2018) James L. Reading et al.   IMMUNOLOGICAL REVIEWS

End-stage renal disease, dialysis, kidney transplantation and their impact on CD4+ T-cell differentiation

(2018) Matthias Schaier et al.   IMMUNOLOGY

Advances on CD8+ Tregs and their potential in transplantation

(2018) Séverine Bézie et al.   TRANSPLANTATION

Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer

(2018) Fleur S. Peters et al.   Clinical Epigenetics

Uraemia-induced immune senescence and clinical outcomes in chronic kidney disease patients

(2018) Thomas Crépin et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients

(2017) Richard Linedale et al.   PLoS One

Incidence of and Risk Factors for Skin Cancer in Organ Transplant Recipients in the United States

(2017) Giorgia L. Garrett et al.   JAMA Dermatology

The Janus Face of Death Receptor Signaling during Tumor Immunoediting

(2016) Eimear O’ Reilly et al.   Frontiers in Immunology

Shifts in subsets of CD8+ T-cells as evidence of immunosenescence in patients with cancers affecting the lungs: an observational case-control study

(2015) Oscar Okwudiri Onyema et al.   BMC CANCER

CD8+ Immunosenescence Predicts Post-Transplant Cutaneous Squamous Cell Carcinoma in High-Risk Patients

(2015) M. J. Bottomley et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The immune phenotype may relate to cancer development in kidney transplant recipients

(2014) Christopher M. Hope et al.   KIDNEY INTERNATIONAL

Epidemiology, contributors to, and clinical trials of mortality risk in chronic kidney failure

(2014) Alberto Ortiz et al.   LANCET

Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage

(2014) Andrew Freeman et al.   PLoS One

Increased Tc22 and Treg/CD8 Ratio Contribute to Aggressive Growth of Transplant Associated Squamous Cell Carcinoma

(2013) Shali Zhang et al.   PLoS One

Kidney Transplant Recipients with Cutaneous Squamous Cell Carcinoma Have an Increased Risk of Internal Malignancy

(2012) Hermina C. Wisgerhof et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Foxp3+ T cells in peripheral blood of renal transplant recipients and clinical correlations

(2012) WEN X LIN et al.   NEPHROLOGY

Premature aging of circulating T cells in patients with end-stage renal disease

(2011) Michiel G.H. Betjes et al.   KIDNEY INTERNATIONAL

Immune Phenotype Predicts Risk for Posttransplantation Squamous Cell Carcinoma

(2010) R. P. Carroll et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aggressive Behavior of Nonmelanotic Skin Cancers in Solid Organ Transplant Recipients

(2010) David G. Lott et al.   TRANSPLANTATION

Antagonistic Roles of CD4+ and CD8+ T-Cells in 7,12-Dimethylbenz(a)anthracene Cutaneous Carcinogenesis

(2008) N. Yusuf et al.   CANCER RESEARCH