Chiral Chlorohydrins from the Biocatalyzed Reduction of Chloroketones: Chiral Building Blocks for Antiretroviral Drugs

Advances in Non-peptidomimetic HIV Protease Inhibitors

(2014) X. Pang et al.   CURRENT MEDICINAL CHEMISTRY

Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis

(2014) Hannes Kohls et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A dynamic niching genetic algorithm strategy for docking highly flexible ligands

(2014) Camila Silva de Magalhães et al.   INFORMATION SCIENCES

Antiretroviral Treatment of Adult HIV Infection

(2014) Huldrych F. Günthard et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Continuous Flow Synthesis of α-Halo Ketones: Essential Building Blocks of Antiretroviral Agents

(2014) Vagner D. Pinho et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoselective Enzyme Cascades: An Efficient Synthesis of Chiral γ-Butyrolactones

(2014) Thomas Classen et al.   ACS Catalysis

Preparation of pharmaceutical important fluorinated 1-arylethanols using isolated enzymes

(2013) Bård Helge Hoff et al.   BIOORGANIC CHEMISTRY

Escherichia coli/ADH-A: An All-Inclusive Catalyst for the Selective Biooxidation and Deracemisation of Secondary Alcohols

(2013) Caroline E. Paul et al.   ChemCatChem

Whole-cell biocatalysis for selective and productive C–O functional group introduction and modification

(2013) Manfred Schrewe et al.   CHEMICAL SOCIETY REVIEWS

Chemoenzymatic Asymmetric Synthesis of Pregabalin Precursors via Asymmetric Bioreduction of β-Cyanoacrylate Esters Using Ene-Reductases

(2013) Christoph K. Winkler et al.   JOURNAL OF ORGANIC CHEMISTRY

Substrate scope and synthetic applications of the enantioselective reduction of α-alkyl-β-arylenones mediated by Old Yellow Enzymes

(2013) Elisabetta Brenna et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structures of Alcohol Dehydrogenases from Ralstonia and Sphingobium spp. Reveal the Molecular Basis for Their Recognition of ‘Bulky–Bulky’ Ketones

(2013) Henry Man et al.   TOPICS IN CATALYSIS

The role of biocatalysis in the asymmetric synthesis of alkaloids

(2013) Joerg H. Schrittwieser et al.   RSC Advances

Dicarbonyl reduction by single enzyme for the preparation of chiral diols

(2012) Yijun Chen et al.   CHEMICAL SOCIETY REVIEWS

Expanding the organic toolbox: a guide to integrating biocatalysis in synthesis

(2012) Christopher M. Clouthier et al.   CHEMICAL SOCIETY REVIEWS

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Al(OtBu)3 as an Effective Catalyst for the Enhancement of Meerwein–Ponndorf–Verley (MPV) Reductions

(2012) Kyle Flack et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Stereocontrol Strategies in the Asymmetric Bioreduction of Alkenes

(2012) Kurt Faber et al.   SYNLETT

Stereo-Controlled Asymmetric Bioreduction of α,β-Dehydroamino Acid Derivatives

(2011) Clemens Stueckler et al.   ADVANCED SYNTHESIS & CATALYSIS

Biocatalytic ketone reduction: A green and efficient access to enantiopure alcohols

(2011) Yan Ni et al.   BIOTECHNOLOGY ADVANCES

Recent Developments of Peptidomimetic HIV-1 Protease Inhibitors

(2011) X. Qiu et al.   CURRENT MEDICINAL CHEMISTRY

New opportunities for biocatalysis: driving the synthesis of chiral chemicals

(2011) Gao-Wei Zheng et al.   CURRENT OPINION IN BIOTECHNOLOGY

Enzymatic reductions for the chemist

(2011) Frank Hollmann et al.   GREEN CHEMISTRY

Biocatalysis: Synthesis of Key Intermediates for Development of Pharmaceuticals

(2011) Ramesh N. Patel   ACS Catalysis

Asymmetric Synthesis of O-Protected Acyloins Using Enoate Reductases: Stereochemical Control through Protecting Group Modification

(2010) Christoph K. Winkler et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Fifteen years of HIV Protease Inhibitors: raising the barrier to resistance

(2009) Annemarie M.J. Wensing et al.   ANTIVIRAL RESEARCH

Highly stereoselective biocatalytic reduction of alpha-halo ketones

(2009) Emmanuelle Alanvert et al.   TETRAHEDRON-ASYMMETRY

Recent progress in biocatalysis for asymmetric oxidation and reduction

(2009) Tomoko Matsuda et al.   TETRAHEDRON-ASYMMETRY

An Exceptionally DMSO-Tolerant Alcohol Dehydrogenase for the Stereoselective Reduction of Ketones

(2008) Iván Lavandera et al.   ChemSusChem

Stereocomplementary Asymmetric Reduction of Bulky–Bulky Ketones by Biocatalytic Hydrogen Transfer

(2008) Iván Lavandera et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Stereoselective Bioreduction of Bulky-Bulky Ketones by a Novel ADH fromRalstoniasp.

(2008) Iván Lavandera et al.   JOURNAL OF ORGANIC CHEMISTRY

One-Way Biohydrogen Transfer for Oxidation ofsec-Alcohols

(2008) Iván Lavandera et al.   ORGANIC LETTERS

Asymmetric anti-Prelog reduction of ketones catalysed by Paracoccus pantotrophus and Comamonas sp. cells via hydrogen transfer

(2008) Iván Lavandera et al.   TETRAHEDRON-ASYMMETRY