Journal
TETRAHEDRON-ASYMMETRY
Volume 20, Issue 21, Pages 2462-2466Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2009.10.008
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The use of recombinant carbonyl reductase biocatalysts for the reduction of alpha-halo ketone intermediates to their corresponding alpha-halo alcohols has been investigated. The alpha-halo alcohol is obtained in good yield from the corresponding ketone in a stereoselective manner. (C) 2009 Elsevier Ltd. All rights reserved.
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