Serinc5 Restricts HIV Membrane Fusion by Altering Lipid Order and Heterogeneity in the Viral Membrane

SERINC5 Restricts HIV-1 Infectivity by Promoting Conformational Changes and Accelerating Functional Inactivation of Env

(2022) Junghwa Kirschman et al.   Viruses-Basel

SERINC5-Mediated Restriction of HIV-1 Infectivity Correlates with Resistance to Cholesterol Extraction but Not with Lipid Order of Viral Membrane

(2022) Gokul Raghunath et al.   Viruses-Basel

Different membrane order measurement techniques are not mutually consistent

(2022) Ankur Gupta et al.   BIOPHYSICAL JOURNAL

Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry

(2021) Jinwoo Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Maturation of the matrix and viral membrane of HIV-1

(2021) Kun Qu et al.   SCIENCE

Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity

(2021) William E. Diehl et al.   Viruses-Basel

Remodeling of Membrane Shape and Topology by Curvature Elasticity and Membrane Tension

(2021) Reinhard Lipowsky   Advanced Biology

A bipartite structural organization defines the SERINC family of HIV-1 restriction factors

(2020) Valerie E. Pye et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lipid Rafts: Controversies Resolved, Mysteries Remain

(2020) Ilya Levental et al.   TRENDS IN CELL BIOLOGY

Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus Fusion by Disrupting Envelope Glycoprotein Clusters

(2020) Yen-Cheng Chen et al.   ACS Nano

Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape

(2020) J. H. Lorent et al.   Nature Chemical Biology

Direct imaging of liquid domains in membranes by cryo-electron tomography

(2020) Caitlin E. Cornell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct label-free imaging of nanodomains in biomimetic and biological membranes by cryogenic electron microscopy

(2020) Frederick A. Heberle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arbidol and other Low Molecular Weight Drugs That Inhibit Lassa and Ebola Viruses

(2019) C. E. Hulseberg et al.   JOURNAL OF VIROLOGY

Mechanosensitive Fluorescent Probes to Image Membrane Tension in Mitochondria, Endoplasmic Reticulum, and Lysosomes

(2019) Antoine Goujon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Roles of phosphatidylserine exposed on the viral envelope and cell membrane in HIV-1 replication

(2019) Bernadette Anne Chua et al.   Cell Communication and Signaling

Flow Cytometry Analysis of HIV-1 Env Conformations at the Surface of Infected Cells and Virions: Role of Nef, CD4, and SERINC5

(2019) Isabelle Staropoli et al.   JOURNAL OF VIROLOGY

HIV-1 Env gp41 Transmembrane Domain Dynamics Are Modulated by Lipid, Water, and Ion Interactions

(2018) Louis R. Hollingsworth et al.   BIOPHYSICAL JOURNAL

Lipid-dependence of target membrane stability during influenza viral fusion

(2018) Sourav Haldar et al.   JOURNAL OF CELL SCIENCE

Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5

(2018) Bianca Schulte et al.   VIROLOGY

A fluorescent membrane tension probe

(2018) Adai Colom et al.   Nature Chemistry

The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles

(2017) Birthe Trautz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins

(2017) Chetan Sood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Structural characterization of membrane-bound human immunodeficiency virus-1 Gag matrix with neutron reflectometry

(2017) Rebecca Eells et al.   Biointerphases

Herpes Simplex Virus 1 Envelope Cholesterol Facilitates Membrane Fusion

(2017) George A. Wudiri et al.   Frontiers in Microbiology

HIV virions sense plasma membrane heterogeneity for cell entry

(2017) Sung-Tae Yang et al.   Science Advances

Membrane tension increases fusion efficiency of model membranes in the presence of SNAREs

(2017) Torben-Tobias Kliesch et al.   Scientific Reports

HIV-1 matrix-31 membrane binding peptide interacts differently with membranes containing PS vs . PI(4,5)P 2

(2016) Lauren O'Neil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Calculating Transition Energy Barriers and Characterizing Activation States for Steps of Fusion

(2016) Rolf J. Ryham et al.   BIOPHYSICAL JOURNAL

The role of cholesterol in membrane fusion

(2016) Sung-Tae Yang et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Effect of HIV-1 Env on SERINC5 Antagonism

(2016) Saina Beitari et al.   JOURNAL OF VIROLOGY

Fusion of Enveloped Viruses in Endosomes

(2016) Judith M. White et al.   TRAFFIC

Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion

(2016) Sung-Tae Yang et al.   Nature Communications

Influenza viral membrane fusion is sensitive to sterol concentration but surprisingly robust to sterol chemical identity

(2016) Katarzyna E. Zawada et al.   Scientific Reports

Functional organization of the HIV lipid envelope

(2016) Nerea Huarte et al.   Scientific Reports

Revisit the Correlation between the Elastic Mechanics and Fusion of Lipid Membranes

(2016) Zih-An Fan et al.   Scientific Reports

The hemifusion structure induced by influenza virus haemagglutinin is determined by physical properties of the target membranes

(2016) Petr Chlanda et al.   Nature Microbiology

Bright and photostable push-pull pyrene dye visualizes lipid order variation between plasma and intracellular membranes

(2016) Yosuke Niko et al.   Scientific Reports

Membrane tension and membrane fusion

(2015) Michael M Kozlov et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Fluorescent Flippers for Mechanosensitive Membrane Probes

(2015) Marta Dal Molin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

(2015) Yoshiko Usami et al.   NATURE

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

(2015) Annachiara Rosa et al.   NATURE

HIV gp41–mediated membrane fusion occurs at edges of cholesterol-rich lipid domains

(2015) Sung-Tae Yang et al.   Nature Chemical Biology

Viral apoptotic mimicry

(2015) Ali Amara et al.   NATURE REVIEWS MICROBIOLOGY

The HIV-1 Entry Process: A Stoichiometric View

(2015) Oliver F. Brandenberg et al.   TRENDS IN MICROBIOLOGY

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

The cholesterol-binding motif of the HIV-1 glycoprotein gp41 regulates lateral sorting and oligomerization

(2014) Roland Schwarzer et al.   CELLULAR MICROBIOLOGY

Multiphasic Effects of Cholesterol on Influenza Fusion Kinetics Reflect Multiple Mechanistic Roles

(2013) Marta K. Domanska et al.   BIOPHYSICAL JOURNAL

Fusion of Mature HIV-1 Particles Leads to Complete Release of a Gag-GFP-Based Content Marker and Raises the Intraviral pH

(2013) Sergi Padilla-Parra et al.   PLoS One

Phase Diagram of Ternary Cholesterol/Palmitoylsphingomyelin/Palmitoyloleoyl-Phosphatidylcholine Mixtures: Spin-Label EPR Study of Lipid-Raft Formation

(2012) Irina V. Ionova et al.   BIOPHYSICAL JOURNAL

Elucidating membrane structure and protein behavior using giant plasma membrane vesicles

(2012) Erdinc Sezgin et al.   Nature Protocols

Size-Dependent Properties of Small Unilamellar Vesicles Formed by Model Lipids

(2011) Chun-Min Lin et al.   LANGMUIR

Mechanics of surface area regulation in cells examined with confined lipid membranes

(2011) M. Staykova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of cholesterol on the rigidity of saturated and unsaturated membranes: fluctuation and electrodeformation analysis of giant vesicles

(2010) Rubèn Serral Gracià et al.   Soft Matter

Probing HIV-1 Membrane Liquid Order by Laurdan Staining Reveals Producer Cell-dependent Differences

(2009) Maier Lorizate et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Gaussian Curvature Elastic Energy of Intermediates in Membrane Fusion

(2008) David P. Siegel   BIOPHYSICAL JOURNAL

Specific Lipids Supply Critical Negative Spontaneous Curvature—An Essential Component of Native Ca2+-Triggered Membrane Fusion

(2008) Matthew A. Churchward et al.   BIOPHYSICAL JOURNAL

Liquid Ordered and Gel Phases of Lipid Bilayers: Fluorescent Probes Reveal Close Fluidity but Different Hydration

(2008) Gora M’Baye et al.   BIOPHYSICAL JOURNAL

Cholesterol Promotes Hemifusion and Pore Widening in Membrane Fusion Induced by Influenza Hemagglutinin

(2008) Subrata Biswas et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mechanics of membrane fusion

(2008) Leonid V Chernomordik et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY