Cell stretching devices as research tools: engineering and biological considerations

Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis

(2016) Cassandra L. Happe et al.   CIRCULATION RESEARCH

Mechanosensitive subcellular rheostasis drives emergent single-cell mechanical homeostasis

(2016) Shinuo Weng et al.   NATURE MATERIALS

Mechanotransduction in neutrophil activation and deactivation

(2015) Andrew E. Ekpenyong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Heading in the Right Direction: Understanding Cellular Orientation Responses to Complex Biophysical Environments

(2015) Chiara Tamiello et al.   Cellular and Molecular Bioengineering

All-silica microfluidic optical stretcher with acoustophoretic prefocusing

(2015) Giovanni Nava et al.   Microfluidics and Nanofluidics

Cyclic stretching of soft substrates induces spreading and growth

(2015) Yidan Cui et al.   Nature Communications

Imaging of a linear diode bar for an optical cell stretcher

(2015) K. B. Roth et al.   Biomedical Optics Express

Microfluidic Organ-on-a-Chip Technology for Advancement of Drug Development and Toxicology

(2015) Jeremy D. Caplin et al.   Advanced Healthcare Materials

Piezoelectric actuator-based cell microstretch device with real-time imaging capability

(2015) Shinji Deguchi et al.   AIP Advances

Global architecture of the F-actin cytoskeleton regulates cell shape-dependent endothelial mechanotransduction

(2014) Yue Shao et al.   Integrative Biology

Engineering living systems on chips: from cells to human on chips

(2014) Yoshitaka Sei et al.   Microfluidics and Nanofluidics

The Direction of Stretch-Induced Cell and Stress Fiber Orientation Depends on Collagen Matrix Stress

(2014) Abhishek Tondon et al.   PLoS One

Design and Construction of an Equibiaxial Cell Stretching System That Is Improved for Biochemical Analysis

(2014) Chaitanya Prashant Ursekar et al.   PLoS One

Mechanical control of cell biology. Effects of cyclic mechanical stretch on cardiomyocyte cellular organization

(2014) Stefan Dhein et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

A microscale mechanical stimulator for generating identical in-plane surface strains toward live cells on multiple loading sites

(2014) Qian Wang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Cell reorientation under cyclic stretching

(2014) Ariel Livne et al.   Nature Communications

Nox Family NADPH Oxidases in Mechano-Transduction: Mechanisms and Consequences

(2013) Ralf P. Brandes et al.   ANTIOXIDANTS & REDOX SIGNALING

A polymeric cell stretching device for real-time imaging with optical microscopy

(2013) Yuli Huang et al.   BIOMEDICAL MICRODEVICES

A microscale anisotropic biaxial cell stretching device for applications in mechanobiology

(2013) Dominique Tremblay et al.   BIOTECHNOLOGY LETTERS

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

Pneumatic cell stretching system for cardiac differentiation and culture

(2013) Joose Kreutzer et al.   MEDICAL ENGINEERING & PHYSICS

Stretchable cell culture platforms using micropneumatic actuators

(2013) Yun Jung Heo et al.   Micro & Nano Letters

Acute Mechanical Stretch Promotes eNOS Activation in Venous Endothelial Cells Mainly via PKA and Akt Pathways

(2013) Zhenqian Hu et al.   PLoS One

Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover

(2013) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uniaxial cell stretching device for live-cell imaging of mechanosensitive cellular functions

(2013) Yue Shao et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Organs on microfluidic chips: A mini review

(2013) Bo Jiang et al.   Science China-Chemistry

Comparison of stresses on homogeneous spheroids in the optical stretcher computed with geometrical optics and generalized Lorenz–Mie theory

(2012) Lars Boyde et al.   APPLIED OPTICS

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

A microfluidic flow-stretch chip for investigating blood vessel biomechanics

(2012) Wenfu Zheng et al.   LAB ON A CHIP

Microfluidic system for cell mechanics analysis through dielectrophoresis

(2012) Isabella Guido et al.   MICROELECTRONIC ENGINEERING

Micropatterned stretching system for the investigation of mechanical tension on neural stem cells behavior

(2012) Yu-Ju Chang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Erythrocyte deformation in high-throughput optical stretchers

(2012) Ihab Sraj et al.   PHYSICAL REVIEW E

Development of Polydimethylsiloxane Substrates with Tunable Elastic Modulus to Study Cell Mechanobiology in Muscle and Nerve

(2012) Rachelle N. Palchesko et al.   PLoS One

Mechanical Stretching for Tissue Engineering: Two-Dimensional and Three-Dimensional Constructs

(2012) Brandon D. Riehl et al.   TISSUE ENGINEERING PART B-REVIEWS

Validation and perspectives of a femtosecond laser fabricated monolithic optical stretcher

(2012) Nicola Bellini et al.   Biomedical Optics Express

Organs-on-a-Chip: A Focus on Compartmentalized Microdevices

(2011) Christopher Moraes et al.   ANNALS OF BIOMEDICAL ENGINEERING

Compound C stimulates heme oxygenase-1 gene expression via the Nrf2-ARE pathway to preserve human endothelial cell survival

(2011) Xiao-Ming Liu et al.   BIOCHEMICAL PHARMACOLOGY

Protein adsorption in three dimensions

(2011) Erwin A. Vogler   BIOMATERIALS

Actuation means for the mechanical stimulation of living cells via microelectromechanical systems: A critical review

(2011) Denis Desmaële et al.   JOURNAL OF BIOMECHANICS

Integrated strain array for cellular mechanobiology studies

(2011) C S Simmons et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

A silicone-based stretchable micropost array membrane for monitoring live-cell subcellular cytoskeletal response

(2011) Jennifer M. Mann et al.   LAB ON A CHIP

A new transparent Bio-MEMS for uni-axial single cell stretching

(2011) R. Fior et al.   MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS

Balancing forces: architectural control of mechanotransduction

(2011) Christopher C. DuFort et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Development of a biochip with serially connected pneumatic balloons for cell-stretching culture

(2011) Kazunori Shimizu et al.   SENSORS AND ACTUATORS B-CHEMICAL

A Stretching Device for High-Resolution Live-Cell Imaging

(2010) Lawrence Huang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Effects of Cyclic Stretch Waveform on Endothelial Cell Morphology Using Fractal Analysis

(2010) Nooshin Haghighipour et al.   ARTIFICIAL ORGANS

Mechanical Characterization of Human Red Blood Cells Under Different Osmotic Conditions by Robotic Manipulation With Optical Tweezers

(2010) Youhua Tan et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Cell deformation cytometry using diode-bar optical stretchers

(2010) Ihab Sraj et al.   JOURNAL OF BIOMEDICAL OPTICS

Mechanical forces alter extracellular matrix synthesis by human periodontal ligament fibroblasts

(2010) Pamela S. Howard et al.   JOURNAL OF PERIODONTAL RESEARCH

Development of a MEMS based dynamic rheometer

(2010) Gordon F. Christopher et al.   LAB ON A CHIP

Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on Micro-Electro-Mechanical-Systems

(2010) N. M. Elman et al.   LAB ON A CHIP

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Cell Mechanics: Dissecting the Physical Responses of Cells to Force

(2009) Brenton D. Hoffman et al.   Annual Review of Biomedical Engineering

Myoblast morphology and organization on biochemically micro-patterned hydrogel coatings under cyclic mechanical strain

(2009) Wylie W. Ahmed et al.   BIOMATERIALS

Cyclic stretch of the substratum using a shape-memory alloy induces directional migration in Dictyostelium cells

(2009) Yoshiaki Iwadate et al.   BIOTECHNIQUES

Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation

(2009) Christopher Moraes et al.   LAB ON A CHIP

Combined atomic force microscopy and side-view optical imaging for mechanical studies of cells

(2009) Ovijit Chaudhuri et al.   NATURE METHODS

The regulatory role of cell mechanics for migration of differentiating myeloid cells

(2009) F. Lautenschlager et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Microplate Compression Method for Elastic Modulus Measurement of Soft and Viscoelastic Collagen Microspheres

(2008) B.P. Chan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Individually programmable cell stretching microwell arrays actuated by a Braille display

(2008) Yoko Kamotani et al.   BIOMATERIALS

A uniaxial bioMEMS device for imaging single cell response during quantitative force-displacement measurements

(2008) David B. Serrell et al.   BIOMEDICAL MICRODEVICES

Stress-Strain Experiments on Individual Collagen Fibrils

(2008) Zhilei L. Shen et al.   BIOPHYSICAL JOURNAL

Responses of single-ventricular myocytes to dynamic axial stretching

(2008) Satoshi Nishimura et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Magnetic microposts for mechanical stimulation of biological cells: Fabrication, characterization, and analysis

(2008) Nathan J. Sniadecki et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

A cell delivery and pre-positioning system utilizing microfluidic devices for dual-beam optical trap-and-stretch

(2008) Chia-Wei Lai et al.   SENSORS AND ACTUATORS B-CHEMICAL

Role of Cyclic Strain Frequency in Regulating the Alignment of Vascular Smooth Muscle Cells In Vitro

(2007) Bo Liu et al.   BIOPHYSICAL JOURNAL