Mini-pillar array for hydrogel-supported 3D culture and high-content histologic analysis of human tumor spheroids

High-Content Assays for Characterizing the Viability and Morphology of 3D Cancer Spheroid Cultures

(2015) Oksana Sirenko et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Morphological and molecular characterization of the human breast epithelial cell line M13SV1 and its tumorigenic derivatives M13SV1-R2-2 and M13SV1-R2-N1

(2015) Sandra Stempin et al.   Cancer Cell International

Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors

(2015) Man Yu et al.   CANCER SCIENCE

Impact of the spheroid model complexity on drug response

(2015) Oliver Ingo Hoffmann et al.   JOURNAL OF BIOTECHNOLOGY

A novel hanging spherical drop system for the generation of cellular spheroids and high throughput combinatorial drug screening

(2015) A. I. Neto et al.   Biomaterials Science

Drug discovery through stem cell-based organoid models

(2014) Adrian Ranga et al.   ADVANCED DRUG DELIVERY REVIEWS

Indirect modulation of sensitivity to 5-fluorouracil by microRNA-96 in human colorectal cancer cells

(2014) Sun-Ah Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo

(2014) John A. Hickman et al.   Biotechnology Journal

In Vitro Treatment of Melanoma Brain Metastasis by Simultaneously Targeting the MAPK and PI3K Signaling Pathways

(2014) Inderjit Daphu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multilayer Spheroids To Quantify Drug Uptake and Diffusion in 3D

(2014) Toni-Marie Achilli et al.   MOLECULAR PHARMACEUTICS

High-Throughput Screening (HTS) of Anticancer Drug Efficacy on a Micropillar/Microwell Chip Platform

(2013) Dong Woo Lee et al.   ANALYTICAL CHEMISTRY

Application of the DataChip/MetaChip technology for the evaluation of ajoene toxicity in vitro

(2013) Dong Woo Lee et al.   ARCHIVES OF TOXICOLOGY

Application of Concave Microwells to Pancreatic Tumor Spheroids Enabling Anticancer Drug Evaluation in a Clinically Relevant Drug Resistance Model

(2013) Sang-Eun Yeon et al.   PLoS One

Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics

(2012) Anne Hellebust et al.   Nanomedicine

Determination of cell survival after irradiation via clonogenic assay versus multiple MTT Assay - A comparative study

(2012) Karl Buch et al.   Radiation Oncology

Plastic pillar inserts for three-dimensional (3D) cell cultures in 96-well plates

(2012) Dong Woo Lee et al.   SENSORS AND ACTUATORS B-CHEMICAL

High drug attrition rates—where are we going wrong?

(2011) Lisa Hutchinson et al.   Nature Reviews Clinical Oncology

Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer

(2011) J. Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Models for prevention and treatment of cancer: Problems vs promises

(2009) Bharat B. Aggarwal et al.   BIOCHEMICAL PHARMACOLOGY

Spheroid-based human endothelial cell microvessel formation in vivo

(2009) Anna M Laib et al.   Nature Protocols

Microscopic imaging techniques for drug discovery

(2007) Andrew Bullen   NATURE REVIEWS DRUG DISCOVERY