Asymmetric Carbon-Carbon Bond Formation under Solventless Conditions in Ball Mills

Organocatalytic activity of α,α-dipeptide derivatives of (S)-proline in the asymmetric aldol reaction in absence of solvent. Evidence for non-covalent π–π interactions in the transition state

(2015) Elizabeth Machuca et al.   TETRAHEDRON LETTERS

Asymmetric Synthesis of α-Amino Acids under Operationally Convenient Conditions

(2014) Manuel Jörres et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations

(2014) José Luis Aceña et al.   AMINO ACIDS

Diastereo- and Enantioselectiveanti-Selective Hydrogenation of α-Amino-β-keto Ester Hydrochlorides and Related Compounds Using Transition-Metal-Chiral-Bisphosphine Catalysts

(2014) Yasumasa Hamada   CHEMICAL RECORD

Expedient Synthesis of Chiral α-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling

(2014) Xi Lu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantiopure 1,2,3-Triazolyl-β-amino Acids via Click Cycloaddition Reaction on Racemic Alkynyl Precursors Followed by Separation of Stereoisomers

(2014) Margarita Escudero-Casao et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Peptide-Catalyzed Conversion of Racemic Oxazol-5(4H)-ones into Enantiomerically Enriched α-Amino Acid Derivatives

(2014) Anthony J. Metrano et al.   JOURNAL OF ORGANIC CHEMISTRY

An Isothiourea-Catalyzed Asymmetric [2,3]-Rearrangement of Allylic Ammonium Ylides

(2014) Thomas H. West et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of ProPhenol Ligands for the Diastereo- and Enantioselective Synthesis of β-Hydroxy-α-amino Esters

(2014) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Asymmetric Hydroboration of α-Dehydroamino Acid Derivatives: Facile Synthesis of Chiral β-Hydroxy-α-amino Acids

(2014) Zhi-Tao He et al.   ORGANIC LETTERS

Ligand-Controlled C(sp3)-H Arylation and Olefination in Synthesis of Unnatural Chiral  -Amino Acids

(2014) J. He et al.   SCIENCE

Multi-step and multi-component organometallic synthesis in one pot using orthogonal mechanochemical reactions

(2014) José G. Hernández et al.   Chemical Science

Synthesis and Evaluation of (S)-Proline-Containing α,β-Dipeptides as Organocatalysts in Solvent-Free Asymmetric Aldol Reactions Under Ball-Milling Conditions

(2014) Elizabeth Machuca et al.   Asian Journal of Organic Chemistry

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 2: Aldol, Mannich addition reactions, deracemization and (S) to (R) interconversion of α-amino acids

(2013) Alexander E. Sorochinsky et al.   AMINO ACIDS

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases; Part 1: alkyl halide alkylations

(2013) Alexander E. Sorochinsky et al.   AMINO ACIDS

Biotechnology in the Production of Pharmaceutical Industry Ingredients: Amino Acids

(2013) Kalin Ivanov et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Click Chemistry for Drug Development and Diverse Chemical–Biology Applications

(2013) Prakasam Thirumurugan et al.   CHEMICAL REVIEWS

Mechanochemical organic synthesis

(2013) Guan-Wu Wang   CHEMICAL SOCIETY REVIEWS

Mechanochemistry of inorganic and organic systems: what is similar, what is different?

(2013) Elena Boldyreva   CHEMICAL SOCIETY REVIEWS

Hallmarks of mechanochemistry: from nanoparticles to technology

(2013) Peter Baláž et al.   CHEMICAL SOCIETY REVIEWS

Solvent-Free and Catalysts-Free Chemistry: A Benign Pathway to Sustainability

(2013) Manoj B. Gawande et al.   ChemSusChem

“Backdoor Induction” of Chirality in Asymmetric Hydrogenation with Rhodium(I) Complexes of Amino Acid Substituted Triphenylphosphane Ligands

(2013) Zoran Kokan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Phosphane-Phosphite Chelators Built on a α-Cyclodextrin Scaffold: Application in Rh-Catalysed Asymmetric Hydrogenation and Hydroformylation

(2013) Matthieu Jouffroy et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic solvent-free hydrogen bonding-mediated asymmetric Michael additions under ball milling conditions

(2013) Manuel Jörres et al.   GREEN CHEMISTRY

Scratching the catalytic surface of mechanochemistry: a multi-component CuAAC reaction using a copper reaction vial

(2013) Teresa L. Cook et al.   GREEN CHEMISTRY

One-pot two-step mechanochemical synthesis: ligand and complex preparation without isolating intermediates

(2013) Michael Ferguson et al.   GREEN CHEMISTRY

Synthesis of fluorine-containing α-amino acids in enantiomerically pure form via homologation of Ni(II) complexes of glycine and alanine Schiff bases

(2013) José Luis Aceña et al.   JOURNAL OF FLUORINE CHEMISTRY

Development of an Air-Stable Nickel Precatalyst for the Amination of Aryl Chlorides, Sulfamates, Mesylates, and Triflates

(2013) Nathaniel H. Park et al.   ORGANIC LETTERS

Novel Bis(1,3,2-diazaphospholidine) Ligands for Asymmetric Catalysis

(2013) Inmaculada Arribas et al.   ORGANOMETALLICS

New Enantiopure P,P-Bidentate Bis(diamidophosphite) Ligands. Application in Asymmetric Rhodium-Catalyzed Hydrogenation

(2013) Maritza J. Bravo et al.   ORGANOMETALLICS

Higher enantioselectivities in thiourea-catalyzed Michael additions under solvent-free conditions

(2013) Martina Hestericová et al.   TETRAHEDRON

Asymmetric synthesis of aminopyrimidine and cyclic guanidine amino acids

(2013) Vicki D. Möschwitzer et al.   TETRAHEDRON LETTERS

Catalytic Mechanisms and Biocatalytic Applications of Aspartate and Methylaspartate Ammonia Lyases

(2012) Marianne de Villiers et al.   ACS Chemical Biology

Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach

(2012) Pankaj Chauhan et al.   Beilstein Journal of Organic Chemistry

Organocatalyst Efficiency in the Michael Additions of Aldehydes to Nitroalkenes in Water and in a Ball-Mill

(2012) Eva Veverková et al.   ChemCatChem

Preparation of Chiral Amino Esters by Asymmetric Phase-Transfer Catalyzed Alkylations of Schiff Bases in a Ball Mill

(2012) Pierrick Nun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Solvent-free one-pot synthesis of 1,2,3-triazole derivatives by the ‘Click’ reaction of alkyl halides or aryl boronic acids, sodium azide and terminal alkynes over a Cu/Al2O3surface under ball-milling

(2012) Nirmalya Mukherjee et al.   GREEN CHEMISTRY

Asymmetric Transfer Hydrogenation Coupled with Dynamic Kinetic Resolution in Water: Synthesis of anti-β-Hydroxy-α-amino Acid Derivatives

(2012) Brinton Seashore-Ludlow et al.   ORGANIC LETTERS

The Large-Scale Synthesis of (S)-N-Boc-bis(4-fluorophenyl)alanine

(2012) Robert B. Appell et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Azide- and Alkyne-Functionalised α- and β3-Amino Acids

(2012) Daniel Pedersen et al.   SYNLETT

Conducting moisture sensitive reactions under mechanochemical conditions

(2012) Daniel C. Waddell et al.   TETRAHEDRON LETTERS

Fast, ligand- and solvent-free copper-catalyzed click reactions in a ball mill

(2011) Rico Thorwirth et al.   CHEMICAL COMMUNICATIONS

Ball milling in organic synthesis: solutions and challenges

(2011) Achim Stolle et al.   CHEMICAL SOCIETY REVIEWS

Mechanochemistry: opportunities for new and cleaner synthesis

(2011) Stuart L. James et al.   CHEMICAL SOCIETY REVIEWS

Fast, Ligand- and Solvent-Free Synthesis of 1,4-Substituted Buta-1,3-diynes by Cu-Catalyzed Homocoupling of Terminal Alkynes in a Ball Mill

(2011) Robert Schmidt et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Aldol Reaction Organocatalyzed by (S)-Proline-Containing Dipeptides: Improved Stereoinduction under Solvent-Free Conditions

(2011) José G. Hernández et al.   JOURNAL OF ORGANIC CHEMISTRY

Large-Scale Synthesis of a Substitutedd-Phenylalanine Using Asymmetric Hydrogenation

(2011) Martin E. Fox et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Efficient ball-mill procedure in the ‘green’ asymmetric aldol reaction organocatalyzed by (S)-proline-containing dipeptides in the presence of water

(2011) José G. Hernández et al.   TETRAHEDRON

Solvent-free asymmetric aldol reaction organocatalyzed by (S)-proline-containing thiodipeptides under ball-milling conditions

(2011) José G. Hernández et al.   TETRAHEDRON

Solvent-free and time-efficient Suzuki–Miyaura reaction in a ball mill: the solid reagent system KF–Al2O3 under inspection

(2010) Franziska Bernhardt et al.   Beilstein Journal of Organic Chemistry

Enantioselective Organocatalytic Strecker Reactions in the Synthesis of α-Amino Acids

(2010) Jürgen Martens   ChemCatChem

Fast copper-, ligand- and solvent-free Sonogashira coupling in a ball mill

(2010) Rico Thorwirth et al.   GREEN CHEMISTRY

Solvent-free direct enantioselective aldol reaction using polystyrene-supported N-sulfonyl-(Ra)-binam-d-prolinamide as a catalyst

(2010) Abraham Bañón-Caballero et al.   GREEN CHEMISTRY

Large-Scale Asymmetric Synthesis of a Cathepsin S Inhibitor

(2010) Jon C. Lorenz et al.   JOURNAL OF ORGANIC CHEMISTRY

Nonlinear effects in proline-catalysed aldol reactions under solvent-free conditions based on the ternary phase behaviour of scalemic proline

(2009) Angelika Bruckmann et al.   CRYSTENGCOMM

Energetic assessment of the Suzuki–Miyaura reaction: a curtate life cycle assessment as an easily understandable and applicable tool for reaction optimization

(2009) Franziska Schneider et al.   GREEN CHEMISTRY

Solvent-free Sonogashira coupling reaction via high speed ball milling

(2009) Dennis A. Fulmer et al.   GREEN CHEMISTRY

Making kinetic and thermodynamic enolates via solvent-free high speed ball milling

(2009) Daniel C. Waddell et al.   GREEN CHEMISTRY

Organocatalytic reactions: effects of ball milling, microwave and ultrasound irradiation

(2008) Angelika Bruckmann et al.   GREEN CHEMISTRY

The Suzuki−Miyaura Reaction under Mechanochemical Conditions§

(2008) Franziska Schneider et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Solvent-free synthesis of naphthopyrans under ball-milling conditions

(2008) Ya-Wei Dong et al.   TETRAHEDRON

Environmentally benign nucleophilic substitution reactions

(2008) Philip Vogel et al.   TETRAHEDRON LETTERS