Two-Step Protein Labeling by Using Lipoic Acid Ligase with Norbornene Substrates and Subsequent Inverse-Electron Demand Diels-Alder Reaction

Finding the Right (Bioorthogonal) Chemistry

(2014) David M. Patterson et al.   ACS Chemical Biology

Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels–Alder reactions

(2014) Anne-Katrin Späte et al.   Beilstein Journal of Organic Chemistry

Diels–Alder Cycloadditions on Synthetic RNA in Mammalian Cells

(2014) Anna Maria Pyka et al.   BIOCONJUGATE CHEMISTRY

Two-Step Protein Labeling Utilizing Lipoic Acid Ligase and Sonogashira Cross-Coupling

(2014) Sebastian Hauke et al.   BIOCONJUGATE CHEMISTRY

Efficient labelling of enzymatically synthesized vinyl-modified DNA by an inverse-electron-demand Diels–Alder reaction

(2014) Holger Bußkamp et al.   CHEMICAL COMMUNICATIONS

Advances in fluorescence labeling strategies for dynamic cellular imaging

(2014) Kevin M Dean et al.   Nature Chemical Biology

Two-Color Glycan Labeling of Live Cells by a Combination of Diels-Alder and Click Chemistry

(2013) Andrea Niederwieser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes

(2013) Jonathan C. T. Carlson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Reactive trans-Cyclooctene Tags with Improved Stability for Diels–Alder Chemistry in Living Systems

(2013) Raffaella Rossin et al.   BIOCONJUGATE CHEMISTRY

Rapid Labeling of Metabolically Engineered Cell-Surface Glycoconjugates with a Carbamate-Linked Cyclopropene Reporter

(2013) Anne-Katrin Späte et al.   BIOCONJUGATE CHEMISTRY

Structural Insights into Incorporation of Norbornene Amino Acids for Click Modification of Proteins

(2013) Sabine Schneider et al.   CHEMBIOCHEM

Fluorescent Live-Cell Imaging of Metabolically Incorporated Unnatural Cyclopropene-Mannosamine Derivatives

(2013) Christian M. Cole et al.   CHEMBIOCHEM

Bioorthogonal chemistry: strategies and recent developments

(2013) Carlo P. Ramil et al.   CHEMICAL COMMUNICATIONS

Norbornenes in Inverse Electron-Demand Diels-Alder Reactions

(2013) Milan Vrabel et al.   CHEMISTRY-A EUROPEAN JOURNAL

trans-Cyclooctene—a stable, voracious dienophile for bioorthogonal labeling

(2013) Ramajeyam Selvaraj et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Genetically Encoded Cyclopropene Directs Rapid, Photoclick-Chemistry-Mediated Protein Labeling in Mammalian Cells

(2012) Zhipeng Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Live-Cell Imaging of Cyclopropene Tags with Fluorogenic Tetrazine Cycloadditions

(2012) Jun Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Magnetic Gram Stain for Bacterial Detection

(2012) Ghyslain Budin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction

(2012) Emine Kaya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amino Acids for Diels-Alder Reactions in Living Cells

(2012) Tilman Plass et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Specific One-Pot Dual Labeling of DNA by Orthogonal Cycloaddition Chemistry

(2012) Juliane Schoch et al.   BIOCONJUGATE CHEMISTRY

Site-Specific Protein Modification Using Lipoic Acid Ligase and Bis-Aryl Hydrazone Formation

(2012) Justin D. Cohen et al.   CHEMBIOCHEM

Preparation of Carbohydrate Arrays by Using Diels-Alder Reactions with Inverse Electron Demand

(2012) Henning S. G. Beckmann et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Diels-Alder-Reaction with inverse-Electron-Demand, a very efficient versatile Click-Reaction Concept for proper Ligation of variable molecular Partners

(2012) Manfred Wiessler et al.   International Journal of Medical Sciences

Fluorophore Targeting to Cellular Proteins via Enzyme-Mediated Azide Ligation and Strain-Promoted Cycloaddition

(2012) Jennifer Z. Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Second-Generation Covalent TMP-Tag for Live Cell Imaging

(2012) Zhixing Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functionalized Cyclopropenes As Bioorthogonal Chemical Reporters

(2012) David M. Patterson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

(2012) Kathrin Lang et al.   Nature Chemistry

Reactive polymer enables efficient in vivo bioorthogonal chemistry

(2012) N. K. Devaraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Guided Engineering of a Pacific Blue Fluorophore Ligase for Specific Protein Imaging in Living Cells

(2011) Justin D. Cohen et al.   BIOCHEMISTRY

Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation

(2011) Mark R. Karver et al.   BIOCONJUGATE CHEMISTRY

Triflic Acid Catalyzed Reductive Coupling Reactions of Carbonyl Compounds with O-, S-, and N-Nucleophiles

(2011) Beate A. Gellert et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemical tags: Applications in live cell fluorescence imaging

(2011) Richard Wombacher et al.   Journal of Biophotonics

Cellular Consequences of Copper Complexes Used To Catalyze Bioorthogonal Click Reactions

(2011) David C. Kennedy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diels–Alder Cycloaddition for Fluorophore Targeting to Specific Proteins inside Living Cells

(2011) Daniel S. Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vivo Chemistry for Pretargeted Tumor Imaging in Live Mice

(2010) Raffaella Rossin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells

(2010) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Synthesis of 7-Aminocoumarin by Buchwald-Hartwig Cross Coupling for Specific Protein Labeling in Living Cells

(2010) Xin Jin et al.   CHEMBIOCHEM

A Trimethoprim-Based Chemical Tag for Live Cell Two-Photon Imaging

(2010) Sarah S. Gallagher et al.   CHEMBIOCHEM

Tetrazine–trans-cyclooctene ligation for the rapid construction of 18F labeled probes

(2010) Zibo Li et al.   CHEMICAL COMMUNICATIONS

Tailored Ligand Acceleration of the Cu-Catalyzed Azide−Alkyne Cycloaddition Reaction: Practical and Mechanistic Implications

(2010) Stanislav I. Presolski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Live-cell super-resolution imaging with trimethoprim conjugates

(2010) Richard Wombacher et al.   NATURE METHODS

A fluorophore ligase for site-specific protein labeling inside living cells

(2010) C. Uttamapinant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AnIn VivoCovalent TMP-Tag Based on Proximity-Induced Reactivity

(2009) Sarah S. Gallagher et al.   ACS Chemical Biology

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition

(2009) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Yeast Display Evolution of a Kinetically Efficient 13-Amino Acid Substrate for Lipoic Acid Ligase

(2009) Sujiet Puthenveetil et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

An Engineered Aryl Azide Ligase for Site-Specific Mapping of Protein-Protein Interactions through Photo-Cross-Linking

(2008) Hemanta Baruah et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

(2008) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

An Engineered Protein Tag for Multiprotein Labeling in Living Cells

(2008) Arnaud Gautier et al.   CHEMISTRY & BIOLOGY

A Photochemical Synthesis of Functionalizedtrans-Cyclooctenes Driven by Metal Complexation

(2008) Maksim Royzen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY