The Hybrid Pyrroloisoindolone-Dehydropyrrolizine Alkaloid (−)-Chlorizidine A Targets Proteins within the Glycolytic Pathway

Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway

(2015) Qiao-Fen Fu et al.   Journal of Hematology & Oncology

An update on therapeutic opportunities offered by cancer glycolytic metabolism

(2014) Carlotta Granchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

(2013) Tony Taldone et al.   JOURNAL OF MEDICINAL CHEMISTRY

Energy Management by Enhanced Glycolysis in G1-phase in Human Colon Cancer Cells In Vitro and In Vivo

(2013) Y. Bao et al.   MOLECULAR CANCER RESEARCH

Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94

(2013) Lauge Farnaes et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chlorizidine, a Cytotoxic 5H-Pyrrolo[2,1-a]isoindol-5-one-Containing Alkaloid from a Marine Streptomyces sp.

(2013) Xavier Alvarez-Mico et al.   ORGANIC LETTERS

Anticancer Agents That Counteract Tumor Glycolysis

(2012) Carlotta Granchi et al.   ChemMedChem

Targeting of Several Glycolytic Enzymes Using RNA Interference Reveals Aldolase Affects Cancer Cell Proliferation through a Non-glycolytic Mechanism

(2012) Carolyn Ritterson Lew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Enolase, a Multifunctional Protein: Its Role on Pathophysiological Situations

(2012) Àngels Díaz-Ramos et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Enzyme Activity in the Crowded Milieu

(2012) Tobias Vöpel et al.   PLoS One

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component

(2012) C. Nicholls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bromophycolide A Targets Heme Crystallization in the Human Malaria Parasite Plasmodium falciparum

(2011) E. Paige Stout et al.   ChemMedChem

GAPDH: A common enzyme with uncommon functions

(2011) Craig Nicholls et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Antibacterials from the Sea

(2010) Chambers C. Hughes et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Optimized Immunoaffinity Fluorescent Method for Natural Product Target Elucidation

(2010) Wei-luen Yu et al.   JOURNAL OF NATURAL PRODUCTS

Novel roles for GAPDH in cell death and carcinogenesis

(2009) A Colell et al.   CELL DEATH AND DIFFERENTIATION

Marinopyrrole A Target Elucidation by Acyl Dye Transfer

(2009) Chambers C. Hughes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Ammosamides: Structures of Cell Cycle Modulators from a Marine-DerivedStreptomycesSpecies

(2008) Chambers C. Hughes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Antipancreatic Tumor Effect by Simultaneously Targeting Hypoxic Cancer Cells With HSP90 Inhibitor and Glycolysis Inhibitor

(2008) X. Cao et al.   CLINICAL CANCER RESEARCH