Simultaneous Use of in Silico Design and a Correlated Mutation Network as a Tool To Efficiently Guide Enzyme Engineering

Computationally designed libraries for rapid enzyme stabilization

(2014) H. J. Wijma et al.   PROTEIN ENGINEERING DESIGN & SELECTION

The Importance of Additive and Non-Additive Mutational Effects in Protein Engineering

(2013) Manfred T. Reetz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Use of ‘small but smart’ libraries to enhance the enantioselectivity of an esterase fromBacillus stearothermophilustowards tetrahydrofuran-3-yl acetate

(2013) Alberto Nobili et al.   FEBS Journal

Key Amino Acid Residues for Reversed or Improved Enantiospecificity of an ω-Transaminase

(2012) Maria Svedendahl Humble et al.   ChemCatChem

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

The α/β-Hydrolase Fold 3DM Database (ABHDB) as a Tool for Protein Engineering

(2010) Robert Kourist et al.   CHEMBIOCHEM

Natural Diversity to Guide Focused Directed Evolution

(2010) Helge Jochens et al.   CHEMBIOCHEM

Increased Enantioselectivity by Engineering Bottleneck Mutants in an Esterase fromPseudomonas fluorescens

(2009) Anna Schließmann et al.   CHEMBIOCHEM

Finding better protein engineering strategies

(2009) Romas J Kazlauskas et al.   Nature Chemical Biology

Correlated mutation analyses on super-family alignments reveal functionally important residues

(2009) Remko K. P. Kuipers et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS