Use of ‘small but smart’ libraries to enhance the enantioselectivity of an esterase fromBacillus stearothermophilustowards tetrahydrofuran-3-yl acetate

Enantioselective preparation of (R) and (S)-3-hydroxycyclopentanone by kinetic resolution

(2012) Bi-Shuang Chen et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Enantioselective synthesis of HIV protease inhibitor amprenavir via Co-catalyzed HKR of 2-(1-azido-2-phenylethyl)oxirane

(2012) Sunita K. Gadakh et al.   TETRAHEDRON-ASYMMETRY

Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions

(2010) Manfred T. Reetz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The role of the GGGX motif in determining the activity and enantioselectivity of pig liver esterase towards tertiary alcohols

(2010) Markus Gall et al.   BIOCATALYSIS AND BIOTRANSFORMATION

The α/β-Hydrolase Fold 3DM Database (ABHDB) as a Tool for Protein Engineering

(2010) Robert Kourist et al.   CHEMBIOCHEM

Natural Diversity to Guide Focused Directed Evolution

(2010) Helge Jochens et al.   CHEMBIOCHEM

Organic solvent-tolerant enzymes

(2009) Noriyuki Doukyu et al.   BIOCHEMICAL ENGINEERING JOURNAL

Increased Enantioselectivity by Engineering Bottleneck Mutants in an Esterase fromPseudomonas fluorescens

(2009) Anna Schließmann et al.   CHEMBIOCHEM

Directed enzyme evolution via small and effective neutral drift libraries

(2008) Rinkoo D Gupta et al.   NATURE METHODS

A one-pot, simple methodology for cassette randomisation and recombination for focused directed evolution

(2008) Aurelio Hidalgo et al.   PROTEIN ENGINEERING DESIGN & SELECTION