Single-cell RNA-seq uncovers dynamic processes orchestrated by RNA-binding protein DDX43 in chromatin remodeling during spermiogenesis

Structure-function analysis of DEAD-box helicase DDX43

(2022) Ravi Shankar Singh et al.   METHODS

DEAD‐box polypeptide 43 facilitates piRNA amplification by actively liberating RNA from Ago3‐piRISC

(2021) Ryo Murakami et al.   EMBO REPORTS

Independent component analysis based gene co-expression network inference (ICAnet) to decipher functional modules for better single-cell clustering and batch integration

(2021) Weixu Wang et al.   NUCLEIC ACIDS RESEARCH

Differential abundance testing on single-cell data using k-nearest neighbor graphs

(2021) Emma Dann et al.   NATURE BIOTECHNOLOGY

Microinjection of antisense oligonucleotides into living mouse testis enables lncRNA function study

(2021) Zhaohui Chen et al.   Cell and Bioscience

Dimensionality reduction by UMAP to visualize physical and genetic interactions

(2020) Michael W. Dorrity et al.   Nature Communications

Generalizing RNA velocity to transient cell states through dynamical modeling

(2020) Volker Bergen et al.   NATURE BIOTECHNOLOGY

Biological and RNA regulatory function of MOV10 in mammalian germ cells

(2019) Kaiqiang Fu et al.   BMC BIOLOGY

Enhanced Crosslinking Immunoprecipitation (eCLIP) Method for Efficient Identification of Protein-bound RNA in Mouse Testis

(2019) Qiushi Xu et al.   Jove-Journal of Visualized Experiments

PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis

(2019) Xiukun Wang et al.   DEVELOPMENT

The dynamics and regulation of chromatin remodeling during spermiogenesis

(2019) Shuang-Li Hao et al.   GENE

LINC00470 Coordinates the Epigenetic Regulation of ELFN2 to Distract GBM Cell Autophagy

(2018) Changhong Liu et al.   MOLECULAR THERAPY

Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

(2018) Yao Chen et al.   CELL RESEARCH

Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis

(2018) Mei Wang et al.   Cell Stem Cell

A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq

(2018) Christopher Daniel Green et al.   DEVELOPMENTAL CELL

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

The adult human testis transcriptional cell atlas

(2018) Jingtao Guo et al.   CELL RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis

(2018) Deqiang Ding et al.   NUCLEIC ACIDS RESEARCH

The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids

(2018) Brian P. Hermann et al.   Cell Reports

The DEAD-box protein DDX43 (HAGE) is a dual RNA-DNA helicase and has a K-homology domain required for full nucleic acid unwinding activity

(2017) Tanu Talwar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells

(2017) Sophie Barral et al.   MOLECULAR CELL

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Single-cell entropy for accurate estimation of differentiation potency from a cell’s transcriptome

(2017) Andrew E. Teschendorff et al.   Nature Communications

Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice

(2016) Q. Fu et al.   BIOLOGY OF REPRODUCTION

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

(2016) Eric L Van Nostrand et al.   NATURE METHODS

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing

(2015) Anastassios Vourekas et al.   GENES & DEVELOPMENT

RNA Clamping by Vasa Assembles a piRNA Amplifier Complex on Transposon Transcripts

(2014) Jordi Xiol et al.   CELL

Chromatin and Transcription Transitions of Mammalian Adult Germline Stem Cells and Spermatogenesis

(2014) Saher Sue Hammoud et al.   Cell Stem Cell

Chd5 orchestrates chromatin remodelling during sperm development

(2014) Wangzhi Li et al.   Nature Communications

PIWI proteins and their interactors in piRNA biogenesis, germline development and gene expression

(2014) Hsueh-Yen Ku et al.   National Science Review

Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B

(2013) E. Montellier et al.   GENES & DEVELOPMENT

Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis

(2013) Haiyun Gan et al.   Nature Communications

Control of Messenger RNA Fate by RNA-Binding Proteins: An Emphasis on Mammalian Spermatogenesis

(2012) R. K. Idler et al.   JOURNAL OF ANDROLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Blockade of Pachytene piRNA Biogenesis Reveals a Novel Requirement for Maintaining Post-Meiotic Germline Genome Integrity

(2012) Ke Zheng et al.   PLoS Genetics

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNF8-Dependent Histone Modifications Regulate Nucleosome Removal during Spermatogenesis

(2010) Lin-Yu Lu et al.   DEVELOPMENTAL CELL

MVH in piRNA processing and gene silencing of retrotransposons

(2010) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway

(2010) K. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic reprogramming of the male genome during gametogenesis and in the zygote

(2010) S Rousseaux et al.   REPRODUCTIVE BIOMEDICINE ONLINE

The TDRD9-MIWI2 Complex Is Essential for piRNA-Mediated Retrotransposon Silencing in the Mouse Male Germline

(2009) Masanobu Shoji et al.   DEVELOPMENTAL CELL

Role of RNA-binding proteins in mammalian spermatogenesis

(2009) Maria Paola Paronetto et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Male infertility caused by spermiogenic defects: Lessons from gene knockouts

(2009) Wei Yan   MOLECULAR AND CELLULAR ENDOCRINOLOGY

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis

(2008) Fang Yang et al.   JOURNAL OF CELL BIOLOGY

DNA Damage Response During Chromatin Remodeling in Elongating Spermatids of Mice1

(2007) Frédéric Leduc et al.   BIOLOGY OF REPRODUCTION