The DEAD-box protein DDX43 (HAGE) is a dual RNA-DNA helicase and has a K-homology domain required for full nucleic acid unwinding activity

Mutational analysis of FANCJ helicase

(2016) Manhong Guo et al.   METHODS

The RNA helicase Mtr4p is a duplex-sensing translocase

(2016) Eric M Patrick et al.   Nature Chemical Biology

HAGE in Triple-Negative Breast Cancer Is a Novel Prognostic, Predictive, and Actionable Biomarker: A Transcriptomic and Protein Expression Analysis

(2015) T. M. A. Abdel-Fatah et al.   CLINICAL CANCER RESEARCH

KH–RNA interactions: back in the groove

(2015) Giuseppe Nicastro et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Synergistic effects of ATP and RNA binding to human DEAD-box protein DDX1

(2015) Julian N. Kellner et al.   NUCLEIC ACIDS RESEARCH

The Q Motif Is Involved in DNA Binding but Not ATP Binding in ChlR1 Helicase

(2015) Hao Ding et al.   PLoS One

RNA Helicase Proteins as Chaperones and Remodelers

(2014) Inga Jarmoskaite et al.   Annual Review of Biochemistry

HAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancer

(2014) T M A Abdel-Fatah et al.   BRITISH JOURNAL OF CANCER

Insight into the Roles of Helicase Motif Ia by Characterizing Fanconi Anemia Group J Protein (FANCJ) Patient Mutations

(2014) Manhong Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Insights into the Coding Region Determinant-binding Protein-RNA Interaction through Site-directed Mutagenesis in the Heterogeneous Nuclear Ribonucleoprotein-K-homology Domains

(2014) Mark Barnes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recombination hotspots attenuate the coupled ATPase and translocase activities of an AddAB-type helicase–nuclease

(2014) Neville S. Gilhooly et al.   NUCLEIC ACIDS RESEARCH

Pisum sativum p68 DEAD-box protein is ATP-dependent RNA helicase and unique bipolar DNA helicase

(2014) Narendra Tuteja et al.   PLANT MOLECULAR BIOLOGY

The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1

(2014) M G Mathieu et al.   Cell Death & Disease

Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase

(2014) Anna L Mallam et al.   eLife

Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera

(2013) Lenz Steimer et al.   NUCLEIC ACIDS RESEARCH

The Helicase HAGE Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Cell Proliferationin Vivo

(2012) Adam J. Linley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p

(2012) Anna L. Mallam et al.   NATURE

Regulation of translocation polarity by helicase domain 1 in SF2B helicases

(2011) Robert A Pugh et al.   EMBO JOURNAL

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The DEXD/H-box RNA Helicase DDX19 Is Regulated by an α-Helical Switch

(2009) Ruairi Collins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Yeast DEAD Box Protein Mss116p Reveals Two Wedges that Crimp RNA

(2009) Mark Del Campo et al.   MOLECULAR CELL

Enabling IMAC purification of low abundance recombinant proteins from E. coli lysates

(2009) Audur Magnusdottir et al.   NATURE METHODS

Translocation and Unwinding Mechanisms of RNA and DNA Helicases

(2008) Anna Marie Pyle   Annual Review of Biophysics

Structure and function of KH domains

(2008) Roberto Valverde et al.   FEBS Journal

A Role for DEAD Box 1 at DNA Double-Strand Breaks

(2008) L. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

DEAD-box proteins can completely separate an RNA duplex using a single ATP

(2008) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

(2008) F. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function of the C-terminal Domain of the DEAD-box Protein Mss116p Analyzed in Vivo and in Vitro

(2007) Georg Mohr et al.   JOURNAL OF MOLECULAR BIOLOGY