Increased Protein Stability and Decreased Protein Turnover in theCaenorhabditis elegansIns/IGF-1daf-2Mutant

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

(2015) Dirk M. Walther et al.   CELL

In Vivo Single-Cell Detection of Metabolic Oscillations in Stem Cells

(2015) Chiara Stringari et al.   Cell Reports

LC–MS Proteomics Analysis of the Insulin/IGF-1-Deficient Caenorhabditis elegans daf-2(e1370) Mutant Reveals Extensive Restructuring of Intermediary Metabolism

(2014) Geert Depuydt et al.   JOURNAL OF PROTEOME RESEARCH

Reduced Insulin/Insulin-like Growth Factor-1 Signaling and Dietary Restriction Inhibit Translation but Preserve Muscle Mass inCaenorhabditis elegans

(2013) Geert Depuydt et al.   MOLECULAR & CELLULAR PROTEOMICS

Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism

(2013) G. J. Stout et al.   Molecular Systems Biology

Insulin/IGF-1 Signaling Regulates Proteasome Activity through the Deubiquitinating Enzyme UBH-4

(2013) Olli Matilainen et al.   Cell Reports

Characterization of the Proteostasis Roles of Glycerol Accumulation, Protein Degradation and Protein Synthesis during Osmotic Stress in C. elegans

(2012) Kristopher Burkewitz et al.   PLoS One

The impact of photo-induced molecular changes of dairy proteins on their ACE-inhibitory peptides and activity

(2011) Barbara Kerkaert et al.   AMINO ACIDS

Trehalose Renders the Dauer Larva of Caenorhabditis elegans Resistant to Extreme Desiccation

(2011) Cihan Erkut et al.   CURRENT BIOLOGY

Trehalose extends longevity in the nematode Caenorhabditis elegans

(2010) Yoko Honda et al.   AGING CELL

Hot topics in aging research: protein translation and TOR signaling, 2010

(2010) Matt Kaeberlein et al.   AGING CELL

A metabolic signature of long life in Caenorhabditis elegans

(2010) Silke Fuchs et al.   BMC BIOLOGY

A photoconvertible reporter of the ubiquitin-proteasome system in vivo

(2010) Geert Hamer et al.   NATURE METHODS

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

(2010) Della C. David et al.   PLOS BIOLOGY

RNAi Screening Implicates a SKN-1–Dependent Transcriptional Response in Stress Resistance and Longevity Deriving from Translation Inhibition

(2010) Jinling Wang et al.   PLoS Genetics

Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial–Lysosomal Axis Theory of Aging

(2009) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms of Protein Stabilization and Prevention of Protein Aggregation by Glycerol

(2009) Vincent Vagenende et al.   BIOCHEMISTRY

Protein aggregation as a paradigm of aging

(2009) Ariel B. Lindner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Lifespan extension by suppression of autophagy genes inCaenorhabditis elegans

(2009) Yasufumi Hashimoto et al.   GENES TO CELLS

Effect of trehalose on protein structure

(2009) Nishant Kumar Jain et al.   PROTEIN SCIENCE

Mitochondrial turnover in liver is fastin vivoand is accelerated by dietary restriction: application of a simple dynamic model

(2008) Satomi Miwa et al.   AGING CELL

Inhibition of a eukaryotic initiation factor (eIF2Bδ/F11A3.2) during adulthood extends lifespan in Caenorhabditis elegans

(2008) Daisuke Tohyama et al.   FASEB JOURNAL

Clustering of Genetically Defined Allele Classes in the Caenorhabditis elegans DAF-2 Insulin/IGF-1 Receptor

(2008) D. S. Patel et al.   GENETICS

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics