Reduced Insulin/Insulin-like Growth Factor-1 Signaling and Dietary Restriction Inhibit Translation but Preserve Muscle Mass inCaenorhabditis elegans

Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?

(2012) David Gems et al.   ANTIOXIDANTS & REDOX SIGNALING

TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO

(2012) Stacey Robida-Stubbs et al.   Cell Metabolism

Enhanced Energy Metabolism Contributes to the Extended Life Span of Calorie-restrictedCaenorhabditis elegans

(2012) Yiyuan Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of photo-induced molecular changes of dairy proteins on their ACE-inhibitory peptides and activity

(2011) Barbara Kerkaert et al.   AMINO ACIDS

The creatine kinase system and pleiotropic effects of creatine

(2011) Theo Wallimann et al.   AMINO ACIDS

A longer and healthier life with TOR down-regulation: genetics and drugs: Figure 1

(2011) Ivana Bjedov et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Life Span Extension via eIF4G Inhibition Is Mediated by Posttranscriptional Remodeling of Stress Response Gene Expression in C. elegans

(2011) Aric N. Rogers et al.   Cell Metabolism

OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Aging Research

(2011) Jae-Seong Yang et al.   PLoS One

drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans

(2010) Tsui-Ting Ching et al.   AGING CELL

Globin-like proteins in Caenorhabditis elegans: in vivo localization, ligand binding and structural properties

(2010) Eva Geuens et al.   BMC BIOCHEMISTRY

A metabolic signature of long life in Caenorhabditis elegans

(2010) Silke Fuchs et al.   BMC BIOLOGY

Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element

(2010) Ling Li et al.   BMC CELL BIOLOGY

Insulin-like Signaling Determines Survival during Stress via Posttranscriptional Mechanisms in C. elegans

(2010) Gawain McColl et al.   Cell Metabolism

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice

(2010) Giuseppe D'Antona et al.   Cell Metabolism

The natural history of Caenorhabditis elegans

(2010) Marie-Anne Félix et al.   CURRENT BIOLOGY

Honoring Clive McCay and 75 Years of Calorie Restriction Research

(2010) Roger B. McDonald et al.   JOURNAL OF NUTRITION

Proteomic Analyses ofCaenorhabditis elegansDauer Larvae and Long-Liveddaf-2Mutants Implicates a Shared Detoxification System in Longevity Assurance

(2010) Laura M. Jones et al.   JOURNAL OF PROTEOME RESEARCH

FoxO1 regulates muscle fiber-type specification and inhibits calcineurin signaling during C2C12 myoblast differentiation

(2010) Yuan Yuan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO

(2010) Eugene Schuster et al.   Molecular Systems Biology

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Deep SAGE analysis of the Caenorhabditis elegans transcriptome

(2010) Peter Ruzanov et al.   NUCLEIC ACIDS RESEARCH

C. elegans Germline-Deficient Mutants Respond to Pathogen Infection Using Shared and Distinct Mechanisms

(2010) Michael TeKippe et al.   PLoS One

RNAi Screening Implicates a SKN-1–Dependent Transcriptional Response in Stress Resistance and Longevity Deriving from Translation Inhibition

(2010) Jinling Wang et al.   PLoS Genetics

Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans

(2009) Kelvin Yen et al.   AGE

The growth hormone receptor gene-disrupted mouse fails to respond to an intermittent fasting diet

(2009) Oge Arum et al.   AGING CELL

Autophagy and amino acid homeostasis are required for chronological longevity inSaccharomyces cerevisiae

(2009) Ashley L. Alvers et al.   AGING CELL

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways inC. elegans

(2009) Eric L. Greer et al.   AGING CELL

Decon2LS: An open-source software package for automated processing and visualization of high resolution mass spectrometry data

(2009) Navdeep Jaitly et al.   BMC BIOINFORMATICS

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Stimulation of Movement in a Quiescent, Hibernation-Like Form of Caenorhabditis elegans by Dopamine Signaling

(2009) M. M. Gaglia et al.   JOURNAL OF NEUROSCIENCE

Mapping protein abundance patterns in the brain using voxelation combined with liquid chromatography and mass spectrometry

(2009) Vladislav A. Petyuk et al.   METHODS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Intestine ultrastructure of the facultative parasite Halicephalobus gingivalis (Nematoda: Panagrolaimidae)

(2009) Pamela Fonderie et al.   NEMATOLOGY

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

(2009) K. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Comparative Functional Analysis of the Caenorhabditis elegans and Drosophila melanogaster Proteomes

(2009) Sabine P Schrimpf et al.   PLOS BIOLOGY

Mass spectrometric proteome analysis suggests anaerobic shift in metabolism of Dauer larvae of Caenorhabditis elegans

(2008) András Mádi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

DAnTE: a statistical tool for quantitative analysis of -omics data

(2008) A. D. Polpitiya et al.   BIOINFORMATICS

Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans

(2008) David Hoogewijs et al.   BMC MOLECULAR BIOLOGY

Yeast Life Span Extension by Depletion of 60S Ribosomal Subunits Is Mediated by Gcn4

(2008) Kristan K. Steffen et al.   CELL

Nutritional Control of Protein Biosynthetic Capacity by Insulin via Myc in Drosophila

(2008) Aurelio A. Teleman et al.   Cell Metabolism

The Target of Rapamycin Pathway Antagonizes pha-4/FoxA to Control Development and Aging

(2008) Karyn L. Sheaffer et al.   CURRENT BIOLOGY

Inhibition of a eukaryotic initiation factor (eIF2Bδ/F11A3.2) during adulthood extends lifespan in Caenorhabditis elegans

(2008) Daisuke Tohyama et al.   FASEB JOURNAL

Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans

(2008) Sakiko Honjoh et al.   NATURE

Identification by machine vision of the rate of motor activity decline as a lifespan predictor in C. elegans

(2008) Ao-Lin Hsu et al.   NEUROBIOLOGY OF AGING

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics