How can platelet proteomics best be used to interrogate disease?

A Practical and Analytical Comparative Study of Gel-Based Top-Down and Gel-Free Bottom-Up Proteomics Including Unbiased Proteoform Detection

(2023) Huriye Ercan et al.   Cells

The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells

(2022) Rafael D. Melani et al.   SCIENCE

Platelet Phenotype Analysis of COVID-19 Patients Reveals Progressive Changes in the Activation of Integrin αIIbβ3, F13A1, the SARS-CoV-2 Target EIF4A1 and Annexin A5

(2022) Huriye Ercan et al.   Frontiers in Cardiovascular Medicine

SARS‐CoV‐2 infection induces soluble platelet activation markers and PAI‐1 in the early moderate stage of COVID‐19

(2022) Abaher O. Al‐Tamimi et al.   International Journal of Laboratory Hematology

TFPI and FXIII negatively and S100A8/A9 and Cystatin C positively correlate with D-dimer in COVID-19

(2022) Anamika Gupta et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Fibrinolytic Proteins and Factor XIII as Predictors of Thrombotic and Hemorrhagic Complications in Hospitalized COVID-19 Patients

(2022) Marina Marchetti et al.   Frontiers in Cardiovascular Medicine

Alterations of the Platelet Proteome in Lung Cancer: Accelerated F13A1 and ER Processing as New Actors in Hypercoagulability

(2021) Huriye Ercan et al.   Cancers

Low FXIII activity levels in intensive care unit hospitalized COVID-19 patients

(2021) Yael Lichter et al.   Thrombosis Journal

Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs

(2020) Özgün Babur et al.   BLOOD

The Integrin Activating Protein Kindlin-3 Is Cleaved in Human Platelets during ST-Elevation Myocardial Infarction

(2019) Bjoern F. Kraemer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparative proteomics reveals unexpected quantitative phosphorylation differences linked to platelet activation state

(2019) G. J. Schmidt et al.   Scientific Reports

Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets

(2018) Stephanie Makhoul et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition

(2016) Florian Beck et al.   BLOOD

Combined Quantification of the Global Proteome, Phosphoproteome, and Proteolytic Cleavage to Characterize Altered Platelet Functions in the Human Scott Syndrome

(2016) Fiorella A. Solari et al.   MOLECULAR & CELLULAR PROTEOMICS

2D gel-based Proteomics: there's life in the old dog yet

(2016) Reiner Westermeier   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Alteration of platelet GPVI signaling in ST-elevation myocardial infarction patients demonstrated by a combination of proteomic, biochemical, and functional approaches

(2016) Paula Vélez et al.   Scientific Reports

A platelet protein biochip rapidly detects an Alzheimer’s disease-specific phenotype

(2014) Michael Veitinger et al.   ACTA NEUROPATHOLOGICA

ADAP interactions with talin and kindlin promote platelet integrin  IIb 3 activation and stable fibrinogen binding

(2014) A. Kasirer-Friede et al.   BLOOD

Dual Mechanism of Integrin αIIbβ3Closure in Procoagulant Platelets

(2013) Nadine J. A. Mattheij et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteoform: a single term describing protein complexity

(2013) Lloyd M Smith et al.   NATURE METHODS

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways

(2012) J. M. Burkhart et al.   BLOOD

Comparative platelet proteome analysis reveals an increase of monoamine oxidase-B protein expression in Alzheimer's disease but not in non-demented Parkinson's disease patients

(2012) Maria Zellner et al.   Journal of Proteomics

Multiplexed Size Separation of Intact Proteins in Solution Phase for Mass Spectrometry

(2009) John C. Tran et al.   ANALYTICAL CHEMISTRY