- Home
- Publications
- Publication Search
- Publication Details
Title
Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors
Authors
Keywords
-
Journal
NEW ENGLAND JOURNAL OF MEDICINE
Volume 388, Issue 10, Pages 898-912
Publisher
Massachusetts Medical Society
Online
2023-03-09
DOI
10.1056/nejmoa2210140
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Development of a Disease-Specific Health-Related Quality of Life Questionnaire (DTF-QoL) for Patients with Desmoid-Type Fibromatosis
- (2022) Anne-Rose W. Schut et al. Cancers
- The epidemiology of desmoid tumors in Denmark
- (2022) Marie Anneberg et al. Cancer Epidemiology
- Evolving strategies for management of desmoid tumor
- (2022) Richard F. Riedel et al. CANCER
- Molecular pathogenesis of desmoid tumor and the role of γ-secretase inhibition
- (2022) Noah Federman npj Precision Oncology
- Extra-abdominal desmoid tumor fibromatosis: a multicenter EMSOS study
- (2021) Pierluigi Cuomo et al. BMC CANCER
- The management of desmoid tumours: A joint global consensus-based guideline approach for adult and paediatric patients
- (2020) Ben Alman et al. EUROPEAN JOURNAL OF CANCER
- Pazopanib or methotrexate–vinblastine combination chemotherapy in adult patients with progressive desmoid tumours (DESMOPAZ): a non-comparative, randomised, open-label, multicentre, phase 2 study
- (2019) Maud Toulmonde et al. LANCET ONCOLOGY
- Prospective development of a patient‐reported outcomes instrument for desmoid tumors or aggressive fibromatosis
- (2019) Mrinal M. Gounder et al. CANCER
- Desmoid fibromatosis through the patients’ eyes: time to change the focus and organisation of care?
- (2018) Olga Husson et al. SUPPORTIVE CARE IN CANCER
- Sorafenib for Advanced and Refractory Desmoid Tumors
- (2018) Mrinal M. Gounder et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis)
- (2017) Shivaani Kummar et al. JOURNAL OF CLINICAL ONCOLOGY
- Notch Signaling in Development, Tissue Homeostasis, and Disease
- (2017) Chris Siebel et al. PHYSIOLOGICAL REVIEWS
- Targeting theNotch pathway: A potential therapeutic approach for desmoid tumors
- (2015) Hui Shang et al. CANCER
- Notch inhibition in desmoids: “Sure it works in practice, but does it work in theory?”
- (2015) Mrinal M. Gounder CANCER
- High-intensity focused ultrasound treatment for intra-abdominal desmoid tumors: a report of four cases
- (2015) Yulan Shi et al. Journal of Medical Ultrasonics
- A Phase I, Dose-Finding Study in Patients with Advanced Solid Malignancies of the Oral -Secretase Inhibitor PF-03084014
- (2014) W. A. Messersmith et al. CLINICAL CANCER RESEARCH
- Safety profile of semagacestat, a gamma-secretase inhibitor: IDENTITY trial findings
- (2014) David B. Henley et al. CURRENT MEDICAL RESEARCH AND OPINION
- Spontaneous Regression of Primary Abdominal Wall Desmoid Tumors: More Common than Previously Thought
- (2013) Sylvie Bonvalot et al. ANNALS OF SURGICAL ONCOLOGY
- γ-Secretase inhibitors and modulators
- (2013) Todd E. Golde et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503)
- (2013) S Sahebjam et al. BRITISH JOURNAL OF CANCER
- Preclinical and Clinical Studies of Gamma Secretase Inhibitors with Docetaxel on Human Breast Tumors
- (2013) A. F. Schott et al. CLINICAL CANCER RESEARCH
- Targeting Notch signaling pathway in cancer: Clinical development advances and challenges
- (2013) Naoko Takebe et al. PHARMACOLOGY & THERAPEUTICS
- Optimal Approach to Sporadic Desmoid Tumors: From Radical Surgery to Observation. Time for a Consensus?
- (2012) Alessandro Gronchi et al. ANNALS OF SURGICAL ONCOLOGY
- Safety and Tolerability of the γ-Secretase Inhibitor Avagacestat in a Phase 2 Study of Mild to Moderate Alzheimer Disease
- (2012) Vladimir Coric et al. ARCHIVES OF NEUROLOGY
- Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
- (2011) A. M. Carothers et al. CANCER RESEARCH
- Prognostic Factors Influencing Progression-Free Survival Determined From a Series of Sporadic Desmoid Tumors: A Wait-and-See Policy According to Tumor Presentation
- (2011) Sébastien Salas et al. JOURNAL OF CLINICAL ONCOLOGY
- Vasomotor Symptoms and Menopause: Findings from the Study of Women's Health across the Nation
- (2011) Rebecca C. Thurston et al. OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA
- Imatinib for progressive and recurrent aggressive fibromatosis (desmoid tumors): an FNCLCC/French Sarcoma Group phase II trial with a long-term follow-up
- (2010) N. Penel et al. ANNALS OF ONCOLOGY
- Efficacy of Imatinib in Aggressive Fibromatosis: Results of a Phase II Multicenter Sarcoma Alliance for Research through Collaboration (SARC) Trial
- (2010) R. Chugh et al. CLINICAL CANCER RESEARCH
- Evaluation of Selective -Secretase Inhibitor PF-03084014 for Its Antitumor Efficacy and Gastrointestinal Safety to Guide Optimal Clinical Trial Design
- (2010) P. Wei et al. MOLECULAR CANCER THERAPEUTICS
- A critical analysis of treatment strategies in desmoid tumours: a review of a series of 106 cases
- (2008) E. Stoeckle et al. EJSO
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More